Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D₃

Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways

(2015) Nikhil N. Kulkarni et al.   MOLECULAR IMMUNOLOGY

IL-15 Links TLR2/1-Induced Macrophage Differentiation to the Vitamin D-Dependent Antimicrobial Pathway

(2014) S. R. Krutzik et al.   JOURNAL OF IMMUNOLOGY

Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes

(2014) L. J. Toltl et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and Positive and Negative Cross-Talk with Bacterial Lipopolysaccharide

(2014) K. Dower et al.   JOURNAL OF IMMUNOLOGY

Vitamin D3 and phenylbutyrate promote development of a human dendritic cell subset displaying enhanced antimicrobial properties

(2014) Anne M. van der Does et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Host-directed therapies against tuberculosis

(2014) Robert John Wilkinson   Lancet Respiratory Medicine

Oral intake of phenylbutyrate with or without vitamin D3upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis

(2013) Akhirunnesa Mily et al.   BMC Pulmonary Medicine

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

(2012) S. Vigne et al.   BLOOD

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

(2012) A. K. Coussens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest

(2012) Long-Zhu Li   WORLD JOURNAL OF GASTROENTEROLOGY

Sodium butyrate inhibits pathogenic yeast growth and enhances the functions of macrophages

(2011) L. N. Nguyen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

(2011) Adrian R Martineau et al.   LANCET

Phenylbutyrate Counteracts Shigella Mediated Downregulation of Cathelicidin in Rabbit Lung and Intestinal Epithelia: A Potential Therapeutic Strategy

(2011) Protim Sarker et al.   PLoS One

Tuberculosis Immunopathology: The Neglected Role of Extracellular Matrix Destruction

(2011) P. T. Elkington et al.   Science Translational Medicine

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

Neutrophils in tuberculosis: friend or foe?

(2011) David M. Lowe et al.   TRENDS IN IMMUNOLOGY

Influence of oral lactoferrin on Mycobacterium tuberculosis induced immunopathology

(2011) Kerry J. Welsh et al.   TUBERCULOSIS

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages

(2011) Damien Portevin et al.   PLoS Pathogens

IL-37 is a fundamental inhibitor of innate immunity

(2010) Marcel F Nold et al.   NATURE IMMUNOLOGY

Phenylbutyrate Induces Antimicrobial Peptide Expression

(2009) J. Steinmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin

(2009) Jae-Min Yuk et al.   Cell Host & Microbe

Acid Resistance in Mycobacterium tuberculosis

(2009) O. H. Vandal et al.   JOURNAL OF BACTERIOLOGY

Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis

(2008) K. E Nnoaham et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest

(2008) S. K. Rampini et al.   MICROBIOLOGY-SGM