Physiology and Pathology of Endosome-to-Golgi Retrograde Sorting

Dissecting Ent3p: the ENTH domain binds different SNAREs via distinct amino acid residues while the C-terminus is sufficient for retrograde transport from endosomes

(2010) Jana Zimmermann et al.   BIOCHEMICAL JOURNAL

Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge

(2010) Bahne Stechmann et al.   CELL

Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

(2010) Jonathan S Bogan et al.   CURRENT OPINION IN CELL BIOLOGY

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing

(2010) Hirokazu Okada et al.   FASEB JOURNAL

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step

(2010) Christopher Esk et al.   JOURNAL OF CELL BIOLOGY

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

(2010) M. Tabuchi et al.   JOURNAL OF CELL SCIENCE

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-  Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

(2010) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

(2010) Sandra I Vieira et al.   Molecular Neurodegeneration

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab7: roles in membrane trafficking and disease

(2009) Ming Zhang et al.   BIOSCIENCE REPORTS

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Sailing with the Wnt: Charting the Wnt processing and secretion route

(2009) Magdalena J. Lorenowicz et al.   EXPERIMENTAL CELL RESEARCH

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism

(2009) S. Vassilopoulos et al.   SCIENCE

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

Retromer

(2008) Juan S Bonifacino et al.   CURRENT OPINION IN CELL BIOLOGY

Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes

(2008) Jiyeon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

ENTH domain proteins are cargo adaptors for multiple SNARE proteins at the TGN endosome

(2008) S. Chidambaram et al.   JOURNAL OF CELL SCIENCE

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

Opposing Activities of the Snx3-Retromer Complex and ESCRT Proteins Mediate Regulated Cargo Sorting at a Common Endosome

(2008) Todd I. Strochlic et al.   MOLECULAR BIOLOGY OF THE CELL

Wingless secretion promotes and requires retromer-dependent cycling of Wntless

(2008) Fillip Port et al.   NATURE CELL BIOLOGY

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

(2008) Xavier Franch-Marro et al.   NATURE CELL BIOLOGY

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Retromer Complex Influences Wnt Secretion by Recycling Wntless from Endosomes to the Trans-Golgi Network

(2007) Tatyana Y. Belenkaya et al.   DEVELOPMENTAL CELL

Wnt Signaling Requires Retromer-Dependent Recycling of MIG-14/Wntless in Wnt-Producing Cells

(2007) Pei-Tzu Yang et al.   DEVELOPMENTAL CELL

C. elegans AP-2 and Retromer Control Wnt Signaling by Regulating MIG-14/Wntless

(2007) Chun-Liang Pan et al.   DEVELOPMENTAL CELL