Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7

Accessibility of Different Histone H3-Binding Domains of UHRF1 Is Allosterically Regulated by Phosphatidylinositol 5-Phosphate

(2014) Kathy A. Gelato et al.   MOLECULAR CELL

Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization

(2014) B. Ashok Reddy et al.   MOLECULAR CELL

Processing of X-ray snapshots from crystals in random orientations

(2014) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity

(2014) Mirna Perusina Lanfranca et al.   Cells

Ubiquitin-specific Protease 7 Is a Regulator of Ubiquitin-conjugating Enzyme UbE2E1

(2013) Feroz Sarkari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for USP7 in DNA Replication

(2013) M. Jagannathan et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

(2012) C. Boutell et al.   JOURNAL OF GENERAL VIROLOGY

Overexpression of the Ubiquitin-Specific Protease 7 Resulting from Transfection or Mutations in the ICP0 Binding Site Accelerates Rather than Depresses Herpes Simplex Virus 1 Gene Expression

(2012) M. Kalamvoki et al.   JOURNAL OF VIROLOGY

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

(2012) Petra Schwertman et al.   NATURE GENETICS

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability

(2012) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beamline 08ID-1, the prime beamline of the Canadian Macromolecular Crystallography Facility

(2011) Pawel Grochulski et al.   JOURNAL OF SYNCHROTRON RADIATION

Proteomic Profiling of the Human Cytomegalovirus UL35 Gene Products Reveals a Role for UL35 in the DNA Repair Response

(2011) J. Salsman et al.   JOURNAL OF VIROLOGY

Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase

(2011) Alex C. Faesen et al.   MOLECULAR CELL

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells

(2011) Zhi Huang et al.   NATURE CELL BIOLOGY

Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein

(2011) Hye-Ra Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

The Herpesvirus Associated Ubiquitin Specific Protease, USP7, Is a Negative Regulator of PML Proteins and PML Nuclear Bodies

(2011) Feroz Sarkari et al.   PLoS One

Control of DNMT1 Abundance in Epigenetic Inheritance by Acetylation, Ubiquitylation, and the Histone Code

(2011) C. Bronner   Science Signaling

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site

(2010) Jianhong Ma et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses

(2010) Caroline E Lilley et al.   EMBO JOURNAL

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1

(2010) Weihua Qin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Further Insight into Substrate Recognition by USP7: Structural and Biochemical Analysis of the HdmX and Hdm2 Interactions with USP7

(2010) Feroz Sarkari et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparison of the Biological and Biochemical Activities of Several Members of the Alphaherpesvirus ICP0 Family of Proteins

(2010) R. D. Everett et al.   JOURNAL OF VIROLOGY

USP7/HAUSP Promotes the Sequence-Specific DNA Binding Activity of p53

(2010) Feroz Sarkari et al.   PLoS One

Biosynthetic Enzyme GMP Synthetase Cooperates with Ubiquitin-Specific Protease 7 in Transcriptional Regulation of Ecdysteroid Target Genes

(2009) J. A. van der Knaap et al.   MOLECULAR AND CELLULAR BIOLOGY

EBNA1-Mediated Recruitment of a Histone H2B Deubiquitylating Complex to the Epstein-Barr Virus Latent Origin of DNA Replication

(2009) Feroz Sarkari et al.   PLoS Pathogens

HSV ICP0 recruits USP7 to modulate TLR-mediated innate response

(2008) S. Daubeuf et al.   BLOOD

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE