Journal
TOXICON
Volume 57, Issue 4, Pages 497-511Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.toxicon.2011.01.002
Keywords
Cancer; Venom; Anti-tumor therapy; Peptides; Arthropod; Biomolecules
Categories
Funding
- Brazilian Federal Agency
- Graduate Education (CAPES) of the Ministry of Education (MEC), Federative Republic of Brazil
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Many active principles produced by animals, plants and microorganisms have been employed in the development of new drugs to treat diseases such as cancer. Among the animals that produce pharmacologically active molecules capable of interfering in human cellular physiology, the highlights are venomous arthropods, such as scorpions, bees, wasps, spiders, ants and caterpillars. The substances found in the venom of these animals present great potential as anti-tumor agents. In this review, we present the main results of years of research involving the active compounds of arthropods venoms that have anticancer activity. (C) 2011 Elsevier Ltd. All rights reserved.
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