Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections

(2015) Barbara Rehermann et al.   HEPATOLOGY

Type I Interferon Protects Antiviral CD8+ T Cells from NK Cell Cytotoxicity

(2014) Haifeng C. Xu et al.   IMMUNITY

Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1

(2014) Josh Crouse et al.   IMMUNITY

Dysfunctional CD8+T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction

(2014) Peter D. Kurktschiev et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

(2014) Charles Wang et al.   NATURE BIOTECHNOLOGY

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

(2014) J. Lucifora et al.   SCIENCE

Reduction of HBV replication prolongs the early immunological response to IFNα therapy

(2013) Anthony T. Tan et al.   JOURNAL OF HEPATOLOGY

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration

(2013) Lena Allweiss et al.   JOURNAL OF HEPATOLOGY

Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes

(2013) Fei Liu et al.   PLoS Pathogens

Cell-Type Specific Interferon Stimulated Gene Staining in Liver Underlies Response to Interferon Therapy in Chronic HBV Infected Patients

(2012) Yanling Zhu et al.   DIGESTIVE DISEASES AND SCIENCES

MxA inhibits hepatitis B virus replication by interaction with hepatitis B core antigen

(2012) Ning Li et al.   HEPATOLOGY

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

(2012) Simon P. Fletcher et al.   HEPATOLOGY

Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B

(2012) Simon P. Fletcher et al.   HEPATOLOGY

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

(2012) Laura Belloni et al.   JOURNAL OF CLINICAL INVESTIGATION

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

(2012) Dimitra Peppa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis

(2012) Amalia Penna et al.   JOURNAL OF HEPATOLOGY

Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B

(2012) Lorenzo Micco et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus Limits Response of Human Hepatocytes to Interferon-α in Chimeric Mice

(2011) Marc Lütgehetmann et al.   GASTROENTEROLOGY

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

Type I interferons: diversity of sources, production pathways and effects on immune responses

(2011) Melissa Swiecki et al.   Current Opinion in Virology

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline

(2010) Milan J. Sonneveld et al.   HEPATOLOGY

Viral load reduction improves activation and function of natural killer cells in patients with chronic hepatitis B

(2010) Eric T.T.L. Tjwa et al.   JOURNAL OF HEPATOLOGY

Interferons Accelerate Decay of Replication-Competent Nucleocapsids of Hepatitis B Virus

(2010) C. Xu et al.   JOURNAL OF VIROLOGY

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection

(2010) Dimitra Peppa et al.   PLoS Pathogens

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

(2008) S. Menne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Production of Recombinant Woodchuck IFNα and Development of Monoclonal Antibodies

(2008) Pedro Berraondo et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12

(2008) J. Crettaz et al.   JOURNAL OF VIROLOGY

Molecular characterization of woodchuck type I interferons and their expression by woodchuck peripheral blood lymphocytes

(2007) Yinping Lu et al.   CYTOKINE