The effects of cytochrome P450 induction by xenobiotics on endobiotic metabolism in pre-clinical safety studies

Synthetic and Natural Compounds that Interact with Human Cytochrome P450 1A2 and Implications in Drug Development

(2012) B. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Updates on Cytochrome P450-Mediated Cardiovascular Drug Interactions

(2009) Judy W M Cheng et al.   AMERICAN JOURNAL OF THERAPEUTICS

3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

(2009) Mona E Aboutabl et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cytochrome P450 and the Biological Clock in Mammals

(2009) Oren Froy   CURRENT DRUG METABOLISM

Role of NF-κB in the Regulation of Cytochrome P450 Enzymes

(2009) Beshay Zordoky et al.   CURRENT DRUG METABOLISM

Hepatic OATP1B Transporters and Nuclear Receptors PXR and CAR: Interplay, Regulation of Drug Disposition Genes, and Single Nucleotide Polymorphisms

(2009) Henriette E. Meyer zu Schwabedissen et al.   MOLECULAR PHARMACEUTICS

A Comparison of the Roles of Peroxisome Proliferator-Activated Receptor and Retinoic Acid Receptor on CYP26 Regulation

(2009) S. Tay et al.   MOLECULAR PHARMACOLOGY

Cross-talk between Transcription Factors AhR and Nrf2: Lessons for Cancer Chemoprevention from Dioxin

(2009) John D. Hayes et al.   TOXICOLOGICAL SCIENCES

The Aryl Hydrocarbon Receptor Activator Benzo[a]pyrene Enhances Vitamin D3 Catabolism in Macrophages

(2009) Manabu Matsunawa et al.   TOXICOLOGICAL SCIENCES

Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes

(2009) Yukihiro Hirose et al.   TOXICOLOGY

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

(2009) Beshay N.M. Zordoky et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

(2008) James P. Hardwick   BIOCHEMICAL PHARMACOLOGY

Species-Specific and Age-Dependent Bile Acid Composition: Aspects on CYP8B and CYP4A Subfamilies in Bile Acid Biosynthesis

(2008) Kerstin Lundell et al.   CURRENT DRUG METABOLISM

New Insights on the Xenobiotic-Sensing Nuclear Receptors in Liver Diseases – CAR and PXR-

(2008) Satoru Kakizaki et al.   CURRENT DRUG METABOLISM

Characterization of Substrate Specificity of Dog CYP1A2 Using CYP1A2-Deficient and Wild-Type Dog Liver Microsomes

(2008) M. Mise et al.   DRUG METABOLISM AND DISPOSITION

Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats

(2008) B. N. M. Zordoky et al.   DRUG METABOLISM AND DISPOSITION

Interplay of Pregnane X receptor with Other Nuclear Receptors on Gene Regulation

(2008) Yun-Ping Lim et al.   Drug Metabolism and Pharmacokinetics

The Roles of Nuclear Receptors CAR and PXR in Hepatic Energy Metabolism

(2008) Yoshihiro Konno et al.   Drug Metabolism and Pharmacokinetics

Cytochrome P450 and gene activation—from pharmacology to cholesterol elimination and regression of atherosclerosis

(2008) Pauli V. Luoma   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

CYP4F3B is induced by PGA1in human liver cells: a regulation of the 20-HETE synthesis

(2008) Joseph Antoun et al.   JOURNAL OF LIPID RESEARCH

Regulatory Cross-Talk between Drug Metabolism and Lipid Homeostasis: Constitutive Androstane Receptor and Pregnane X Receptor Increase Insig-1 Expression

(2008) A. Roth et al.   MOLECULAR PHARMACOLOGY

Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes

(2008) Adrian Roth et al.   Pharmacogenetics and Genomics

Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells

(2008) Beshay N.M. Zordoky et al.   VASCULAR PHARMACOLOGY