Journal
TOXICOLOGY MECHANISMS AND METHODS
Volume 18, Issue 2-3, Pages 159-175Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/15376510701857460
Keywords
MCASE; MC4PC; CASE; prediction; QSAR; toxicity; mutagenicity; Carcinogenicity; environmental; FDA; expert system; in silico; REACH
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This article is a review of the MultiCASE Inc. software and expert systems and their use to assess acute toxicity, mutagenicity, carcinogenicity, and other health effects. It is demonstrated that MultiCASE expert systems satisfy the guidelines of the Organisation for Economic Cooperation and Development (OECD) principles and that the portfolio of available endpoints closely overlaps with the list of tests required by REACH.
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