The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling

Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis

(2015) K. S. Morawa et al.   DEVELOPMENT

Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System

(2015) Georg F. Vogel et al.   TRAFFIC

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

CC2D1A Regulates Human Intellectual and Social Function as well as NF-κB Signaling Homeostasis

(2014) M. Chiara Manzini et al.   Cell Reports

Phosphodiesterase activity is regulated by CC2D1A that is implicated in non-syndromic intellectual disability

(2013) Azza Al-Tawashi et al.   Cell Communication and Signaling

Protein Implicated in Nonsyndromic Mental Retardation Regulates Protein Kinase A (PKA) Activity

(2012) Azza Al-Tawashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TBK1-associated Protein in Endolysosomes (TAPE)/CC2D1A Is a Key Regulator Linking RIG-I-like Receptors to Antiviral Immunity

(2012) Kuan-Ru Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4

(2012) T. Troost et al.   JOURNAL OF CELL SCIENCE

Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosome

(2012) M. Schneider et al.   JOURNAL OF CELL SCIENCE

CC2D1A Is a Regulator of ESCRT-III CHMP4B

(2012) Nicolas Martinelli et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of CHMP4/ESCRT-III Function in Human Immunodeficiency Virus Type 1 Budding by CC2D1A

(2012) Y. Usami et al.   JOURNAL OF VIROLOGY

Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations

(2012) T Yamada et al.   ONCOGENE

Cc2d1a, a C2 domain containing protein linked to nonsyndromic mental retardation, controls functional maturation of central synapses

(2011) Meng Zhao et al.   JOURNAL OF NEUROPHYSIOLOGY

Notch in the Vertebrate Nervous System: An Old Dog with New Tricks

(2011) Tarran Pierfelice et al.   NEURON

Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice

(2011) Silvia Fre et al.   PLoS One

The ESCRT complexes

(2010) James H. Hurley   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

TBK1-associated Protein in Endolysosomes (TAPE) Is an Innate Immune Regulator Modulating the TLR3 and TLR4 Signaling Pathways

(2010) Chun-Hung Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CC2D1A, a DM14 and C2 Domain Protein, Activates NF-κB through the Canonical Pathway

(2010) Meng Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systems survey of endocytosis by multiparametric image analysis

(2010) Claudio Collinet et al.   NATURE

Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies: Figure 1

(2009) Emily R. Eden et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Human Freud-2/CC2D1B: A Novel Repressor of Postsynaptic Serotonin-1A Receptor Expression

(2009) Mahmoud R. Hadjighassem et al.   BIOLOGICAL PSYCHIATRY

Endocytic regulation of Notch signaling

(2009) Mark E Fortini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement

(2009) Akito Nakamura et al.   JOURNAL OF CELL BIOLOGY

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Freud-1/Aki1, a Novel PDK1-Interacting Protein, Functions as a Scaffold To Activate the PDK1/Akt Pathway in Epidermal Growth Factor Signaling

(2008) A. Nakamura et al.   MOLECULAR AND CELLULAR BIOLOGY

AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand

(2008) Patricia Chastagner et al.   PLoS One