Article
Biochemistry & Molecular Biology
Azza A. A. Attia, Jehan M. M. Sorour, Neama A. A. Mohamed, Tagreed T. T. Mansour, Rasha A. A. Al-Eisa, Nahla S. S. El-Shenawy
Summary: This study aimed to investigate the protective role of vitamin E in improving cardiotoxicity induced by cyclophosphamide in rats. The results showed that vitamin E could attenuate the elevation of cardiac markers, increase in lipid profiles, reduction in antioxidant enzyme activities, and increase in lipid peroxidation. In addition, vitamin E was found to improve the histopathological alterations caused by cyclophosphamide.
Article
Fisheries
Xiaobo Yan, Simiao Pan, Xiaohui Dong, Beiping Tan, Tao Li, Weibin Huang, Xiangxiang Suo, Zhihao Li, Yuanzhi Yang
Summary: This experiment found that adding an appropriate amount of vitamin E to high-lipid diet can improve the antioxidant capacity and immunity of grouper, and may alleviate lipid peroxidation-induced inflammatory responses.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Olamide Adebiyi, Kabirat Adigun, Praise David-Odewumi, Uthman Akindele, Funsho Olayemi
Summary: The study investigated the neuroprotective effects of gallic and ascorbic acids in CdCl2-induced neurotoxicity. The results showed that gallic and ascorbic acids can enhance learning and memory, decrease anxiety and depressive-like behavior, and protect myelin in CdCl2-induced neurotoxicity.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Juliana da Silva Fonseca, Miguel Mies, Alana Paranhos, Satie Taniguchi, Arthur Z. Guth, Marcia C. Bicego, Joseane Aparecida Marques, Laura Fernandes de Barros Marangoni, Adalto Bianchini
Summary: This study investigated the combined effects of thermal stress and copper exposure on the trophic behavior and oxidative status of the reef-building coral Mussismilia harttii. The findings showed that the trophic behavior remained mostly autotrophic under individual and combined stressors, while the 12-day experiment revealed changes in heterotrophy markers. Additionally, different responses were observed in LPO and TAC levels for both coral and symbiont under the combined stressors, highlighting the differential physiological responses of host and symbionts to global and local stressors.
ENVIRONMENTAL POLLUTION
(2021)
Article
Agriculture, Multidisciplinary
Boris Rabkin, Oren Tirosh, Joseph Kanner
Summary: The stomach acts as a bioreactor and plays a crucial role in biochemical reactions that impact human health. The oxidation of meat lipids in the stomach generates malondialdehyde (MDA), which is then absorbed into the bloodstream and modifies low-density lipoprotein (LDL) to MDA-LDL. The study found that vitamin E exhibits strong antioxidant activity against meat lipid oxidation in the stomach, especially at pH 3.0. The antioxidant activity of vitamin E at pH 3.0 is 20 times higher than that of catechin. Additionally, when combined with metmyoglobin (MbFe(+3)), vitamin E acts synergistically as a peroxidase/antioxidant couple, surpassing the antioxidant effect achieved by MbFe(+3)/catechin 150-fold. The continuous addition of low concentrations of vitamin E, catechin, and vitamin C helps maintain the meat's antioxidant activity, preventing lipid oxidation, reactive aldehyde generation, and loss of vitamin E.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Agriculture, Dairy & Animal Science
X. M. Ding, Y. D. Mu, K. Y. Zhang, J. P. Wang, S. P. Bai, Q. F. Zeng, H. W. Peng
Summary: Aged corn negatively affected lipid metabolism and antioxidant function in laying hens. Dietary VE supplementation did not mitigate the detrimental effects of aged corn on lipid metabolism, but 100 IU/kg VE did prevent lipid peroxidation induced by aged corn in the organs of laying hens.
Article
Biochemistry & Molecular Biology
Yoshiro Saito
Summary: Lipid peroxidation and its products play a significant role in physiological and pathophysiological conditions, with mechanisms including enzymatic oxidation, free radical-mediated oxidation, and nonradical-mediated oxidation. The products of lipid peroxidation can lead to cytotoxicity and novel biological activity, while the antioxidant system, particularly selenoproteins and vitamin E, plays a crucial role in preventing lipid peroxidation and ferroptosis.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Anamaria Magdalena Tomsa, Andreea Liana Rachisan, Stanca Lucia Pandrea, Andreea Benea, Ana Uifalean, Corina Toma, Roxana Popa, Alina Elena Parvu, Lia Monica Junie
Summary: This study aimed to investigate the nephroprotective effects of curcumin and vitamin C and the potential use of reactive species as markers for early gentamicin-induced nephrotoxicity. The results demonstrated that supplementation with curcumin and vitamin C could reduce oxidative stress and protect renal function. Vitamin C exhibited a distinctive modulation of nitric oxide and malondialdehyde levels, and histological analysis showed less severe lesions in rats that received vitamin C compared to the curcumin group.
Article
Fisheries
Oleksandr Malinovskyi, Samad Rahimnejad, Vlastimil Stejskal, Dominik Bonko, Alzbeta Stara, Josef Velisek, Tomas Policar
Summary: This study revealed that photoperiod duration significantly affects the growth rate and antioxidant capacity of largemouth bass. The 8L:16D group showed the best performance in terms of growth, organosomatic index, and antioxidant capacity. Longer light duration led to oxidative stress in fish liver, brain, and gill, but also boosted antioxidant responses in liver, brain, and kidney.
Review
Fisheries
Abdel-Fattah M. El-Sayed, Marisol Izquierdo
Summary: Vitamin E plays a crucial role in farmed fish, providing antioxidant protection, improving immune response and growth performance, reducing muscle degeneration and atherosclerosis risk, enhancing reproductive efficiency and product quality. Consideration should be given to the interaction of VE with vitamin C and selenium, as well as lipid content in feed when supplementing VE.
REVIEWS IN AQUACULTURE
(2022)
Article
Cell Biology
Oluwatoyin O. Ojo, Ifedayo M. Obaidu, Oluwatosin C. Obigade, Olufunso O. Olorunsogo
Summary: Apoptosis is increased in diabetes and mitochondria play a crucial role in the pathophysiology of diabetes. Quercetin and vitamin E have shown potential in delaying diabetes-induced complications, potentially by regulating the opening of the mitochondrial permeability transition (mPT) pore. The study found that quercetin and vitamin E treatment reversed the increased swelling and lipid peroxidation in diabetic hearts, suggesting their anti-apoptotic effect by inhibiting mPT pore and modulating mitochondrial-mediated apoptosis.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2022)
Article
Chemistry, Applied
Mengjie Geng, Xumei Feng, Xixi Wu, Xiangyun Tan, Zengnan Liu, Lijia Li, Yuyang Huang, Fei Teng, Yang Li
Summary: A core-shell structure based on soy protein isolate (SPI) and pectin was constructed as a delivery system for vitamins C and E. The SPI-vitamin-pectin complex formed at pH 4.0 showed better encapsulation efficiency and larger particle size compared to that formed at pH 7.0. Additionally, the addition of vitamin C enhanced the encapsulation efficiency of vitamin E and increased the antioxidant properties of the system.
Article
Neurosciences
Irene Villalon-Garcia, Monica Alvarez-Cordoba, Suleva Povea-Cabello, Marta Talaveron-Rey, Marina Villanueva-Paz, Raquel Luzon-Hidalgo, Juan M. Suarez-Rivero, Alejandra Suarez-Carrillo, Manuel Munuera-Cabeza, Joaquin J. Salas, Rafael Falcon-Moya, Antonio Rodriguez-Moreno, Jose A. Armengol, Jose A. Sanchez-Alcazar
Summary: In this study, the presence of lipid peroxidation, iron accumulation and mitochondrial dysfunction in two cellular models of PLA2G6-Associated Neurodegeneration (PLAN) was examined. Vitamin E was found to reverse the pathological features in both models, suggesting its potential as a therapeutic target for the disease.
NEUROBIOLOGY OF DISEASE
(2022)
Article
Veterinary Sciences
Katarina Kuckova, L'ubomira Gresakova, Margareta Takacsova, Anna Kandricakova, L'ubica Chrastinova, Maria Polacikova, Adam Cieslak, Sylwester Slusarczyk, Klaudia Cobanova
Summary: The study showed that the simultaneous administration of organic zinc and thyme extract can significantly improve the antioxidant response of rabbit kidneys, providing a positive effect on the antioxidant status of growing rabbits.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
Phung Diep Huy Vu, Akkaratch Rodklongtan, Pakamon Chitprasert
Summary: The study found that the encapsulant weight ratio of whey protein isolate-lignin complex significantly affects the survival rate of spray-dried probiotics, with the 9:1 ratio offering the best protection. Lignin improves the survival of probiotics by enhancing the structure and antioxidant properties of WPI.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
