Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10

Induction and dorsal restriction of Paired-box 3 (Pax3) gene expression in the caudal neuroectoderm is mediated by integration of multiple pathways on a short neural crest enhancer

(2014) Oraly Sanchez-Ferras et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Colonizing while migrating: how do individual enteric neural crest cells behave?

(2014) Heather M Young et al.   BMC BIOLOGY

An emerging phenotype of Xq22 microdeletions in females with severe intellectual disability, hypotonia and behavioral abnormalities

(2014) Toshiyuki Yamamoto et al.   JOURNAL OF HUMAN GENETICS

X chromosome regulation: diverse patterns in development, tissues and disease

(2014) Xinxian Deng et al.   NATURE REVIEWS GENETICS

Chromosomal Contact Permits Transcription between Coregulated Genes

(2013) Stephanie Fanucchi et al.   CELL

Enteric neural crest-derived cells promote their migration by modifying their microenvironment through tenascin-C production

(2013) Sophia E. Akbareian et al.   DEVELOPMENTAL BIOLOGY

Contribution of rare and common variants determine complex diseases—Hirschsprung disease as a model

(2013) Maria M. Alves et al.   DEVELOPMENTAL BIOLOGY

The Properties of Genome Conformation and Spatial Gene Interaction and Regulation Networks of Normal and Malignant Human Cell Types

(2013) Zheng Wang et al.   PLoS One

In Vivo Analysis of Lrig Genes Reveals Redundant and Independent Functions in the Inner Ear

(2013) Tony del Rio et al.   PLoS Genetics

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

The developmental genetics of Hirschsprung's disease

(2012) K-F Bergeron et al.   CLINICAL GENETICS

Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes

(2012) J. T. Wolstenholme et al.   GENES BRAIN AND BEHAVIOR

Caudal-related Homeobox (Cdx) Protein-dependent Integration of Canonical Wnt Signaling on Paired-box 3 (Pax3) Neural Crest Enhancer

(2012) Oraly Sanchez- Ferras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of long-range chromatin interactions using Chromosome Conformation Capture

(2012) Natalia Naumova et al.   METHODS

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system

(2012) Chihiro Nishiyama et al.   NATURE NEUROSCIENCE

Development and developmental disorders of the enteric nervous system

(2012) Florian Obermayr et al.   Nature Reviews Gastroenterology & Hepatology

Gdnf is mitogenic, neurotrophic, and chemoattractive to enteric neural crest cells in the embryonic colon

(2011) Olive Mwizerwa et al.   DEVELOPMENTAL DYNAMICS

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans

(2011) Elly Sau-Wai Ngan et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Background Strongly Modifies the Severity of Symptoms of Hirschsprung Disease, but Not Hearing Loss in Rats Carrying Ednrbsl Mutations

(2011) Ruihua Dang et al.   PLoS One

Age-dependent changes in the gut environment restrict the invasion of the hindgut by enteric neural progenitors

(2009) N. R. Druckenbrod et al.   DEVELOPMENT

Effects of tissue age, presence of neurones and endothelin-3 on the ability of enteric neurone precursors to colonize recipient gut: implications for cell-based therapies

(2009) r. hotta et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Spatial and Temporal Analysis of Gene Expression during Growth and Fusion of the Mouse Facial Prominences

(2009) Weiguo Feng et al.   PLoS One

Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells

(2008) Nicolas Pilon et al.   DEVELOPMENTAL DYNAMICS

Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice

(2008) Toshihiro Uesaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Lrig1 Is an Endogenous Inhibitor of Ret Receptor Tyrosine Kinase Activation, Downstream Signaling, and Biological Responses to GDNF

(2008) F. Ledda et al.   JOURNAL OF NEUROSCIENCE

Identification of Neural Crest and Glial Enhancers at the Mouse Sox10 Locus through Transgenesis in Zebrafish

(2008) Anthony Antonellis et al.   PLoS Genetics