APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans

Distinct Roles for Inhibition in Spatial and Temporal Tuning of Local Edge Detectors in the Rabbit Retina

(2014) Sowmya Venkataramani et al.   PLoS One

Education influences the role of genetics in myopia

(2013) Virginie J. M. Verhoeven et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Photopic visual input is necessary for emmetropization in mice

(2013) Tatiana V. Tkatchenko et al.   EXPERIMENTAL EYE RESEARCH

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

(2013) Virginie J M Verhoeven et al.   NATURE GENETICS

Hippocampal Network Oscillations in APP/APLP2-Deficient Mice

(2013) Xiaomin Zhang et al.   PLoS One

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

(2013) Amy K. Kiefer et al.   PLoS Genetics

Quantifying Missing Heritability at Known GWAS Loci

(2013) Alexander Gusev et al.   PLoS Genetics

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Inhibitory mechanisms that generate centre and surround properties in ON and OFF brisk-sustained ganglion cells in the rabbit retina

(2012) Ilya Buldyrev et al.   JOURNAL OF PHYSIOLOGY-LONDON

The complex interactions of retinal, optical and environmental factors in myopia aetiology

(2012) D.I. Flitcroft   PROGRESS IN RETINAL AND EYE RESEARCH

Receptor targets of amacrine cells

(2012) CHI ZHANG et al.   VISUAL NEUROSCIENCE

Genetic Variants at 13q12.12 Are Associated with High Myopia in the Han Chinese Population

(2011) Yi Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

(2011) Sascha W Weyer et al.   EMBO JOURNAL

A genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population

(2011) Zhiqiang Li et al.   HUMAN MOLECULAR GENETICS

Synaptic pathways that shape the excitatory drive in an OFF retinal ganglion cell

(2011) Ilya Buldyrev et al.   JOURNAL OF NEUROPHYSIOLOGY

Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants

(2011) J.-H. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celsr3 Is Required for Normal Development of GABA Circuits in the Inner Retina

(2011) Alaron Lewis et al.   PLoS Genetics

The role of APP and APLP for synaptic transmission, plasticity, and network function: lessons from genetic mouse models

(2011) Martin Korte et al.   EXPERIMENTAL BRAIN RESEARCH

Functions of the APP gene family in the nervous system: insights from mouse models

(2011) Dorothee Aydin et al.   EXPERIMENTAL BRAIN RESEARCH

Nature and nurture: the complex genetics of myopia and refractive error

(2010) R Wojciechowski   CLINICAL GENETICS

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Retinal Synaptic Pathways Underlying the Response of the Rabbit Local Edge Detector

(2010) Thomas L. Russell et al.   JOURNAL OF NEUROPHYSIOLOGY

Ketamine–xylazine anesthesia causes hyperopic refractive shift in mice

(2010) Tatiana V. Tkatchenko et al.   JOURNAL OF NEUROSCIENCE METHODS

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

(2010) Pirro G Hysi et al.   NATURE GENETICS

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14

(2010) Abbas M Solouki et al.   NATURE GENETICS

Genome-Wide Association Studies Reveal Genetic Variants in CTNND2 for High Myopia in Singapore Chinese

(2010) Yi-Ju Li et al.   OPHTHALMOLOGY

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

(2010) A. Eyre-Walker   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The GEnes in Myopia (GEM) study in understanding the aetiology of refractive errors

(2010) Paul N. Baird et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Six different roles for crossover inhibition in the retina: Correcting the nonlinearities of synaptic transmission

(2010) FRANK S. WERBLIN   VISUAL NEUROSCIENCE

Heritability Analysis of Spherical Equivalent, Axial Length, Corneal Curvature, and Anterior Chamber Depth in the Beaver Dam Eye Study

(2009) Alison P. Klein   ARCHIVES OF OPHTHALMOLOGY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Relative peripheral hyperopic defocus alters central refractive development in infant monkeys

(2009) Earl L. Smith et al.   VISION RESEARCH

A Genome-Wide Association Analysis Identified a Novel Susceptible Locus for Pathological Myopia at 11q24.1

(2009) Hideo Nakanishi et al.   PLoS Genetics

Glycinergic transmission in the mammalian retina

(2009) Heinz Wässle   Frontiers in Molecular Neuroscience

Genome-wide Scan of African-American and White Families for Linkage to Myopia

(2008) Elise Ciner et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Prevalence of Refractive Error in the United States, 1999-2004

(2008) Susan Vitale   ARCHIVES OF OPHTHALMOLOGY

New susceptibility locus for high myopia is linked to the uromodulin-like 1 (UMODL1) gene region on chromosome 21q22.3

(2008) R Nishizaki et al.   EYE

Genomewide scan of ocular refraction in African‐American families shows significant linkage to chromosome 7p15

(2008) Elise Ciner et al.   GENETIC EPIDEMIOLOGY

Molecular Genetics of Human Myopia: An Update

(2008) Terri L. Young   OPTOMETRY AND VISION SCIENCE

Embryonic Stem Cell-Derived Neurons as a Cellular System to Study Gene Function: Lack of Amyloid Precursor Proteins APP and APLP2 Leads to Defective Synaptic Transmission

(2008) Katrin Schrenk-Siemens et al.   STEM CELLS

Spectacle lens compensation in the pigmented guinea pig

(2008) Marcus H.C. Howlett et al.   VISION RESEARCH