Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

Discontinuous leading-strand synthesis: a stop–start story

(2014) Joseph T.P. Yeeles   BIOCHEMICAL SOCIETY TRANSACTIONS

A Common Cancer-Associated DNA Polymerase   Mutation Causes an Exceptionally Strong Mutator Phenotype, Indicating Fidelity Defects Distinct from Loss of Proofreading

(2014) D. P. Kane et al.   CANCER RESEARCH

Replicative DNA polymerase mutations in cancer

(2014) Ellen Heitzer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

DNA Replication Error-Induced Extinction of Diploid Yeast

(2014) A. J. Herr et al.   GENETICS

Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms

(2014) Carolina B. Gabbai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork

(2014) Roxana E Georgescu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Oxidative Damage and Mutagenesis in Saccharomyces cerevisiae: Genetic Studies of Pathways Affecting Replication Fidelity of 8-Oxoguanine

(2013) A. H. Shockley et al.   GENETICS

Emergence of DNA Polymerase   Antimutators That Escape Error-Induced Extinction in Yeast

(2013) L. N. Williams et al.   GENETICS

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

(2013) David N. Church et al.   HUMAN MOLECULAR GENETICS

Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

(2013) Medini Manohar Ghodgaonkar et al.   MOLECULAR CELL

Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors

(2013) Scott A. Lujan et al.   MOLECULAR CELL

Error bars

(2013) Martin Krzywinski et al.   NATURE METHODS

Different Roles of Eukaryotic MutS and MutL Complexes in Repair of Small Insertion and Deletion Loops in Yeast

(2013) Nina V. Romanova et al.   PLoS Genetics

In Vivo Bypass of 8-oxodG

(2013) Gina P. Rodriguez et al.   PLoS Genetics

DNA polymerase delta in dna replication and genome maintenance

(2012) Marc J. Prindle et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

(2012) Claire Palles et al.   NATURE GENETICS

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

(2012) Peter A. Carr et al.   NUCLEIC ACIDS RESEARCH

Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering

(2012) M. J. Lajoie et al.   NUCLEIC ACIDS RESEARCH

Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases

(2012) Xavier Rios et al.   PLoS One

Transformation with Oligonucleotides Creating Clustered Changes in the Yeast Genome

(2012) Gina P. Rodriguez et al.   PLoS One

Mismatch repair-dependent mutagenesis in nondividing cells

(2012) G. P. Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity

(2012) Scott A. Lujan et al.   PLoS Genetics

Characterization of MSH2 variants by endogenous gene modification in mouse embryonic stem cells

(2011) Eva A.L. Wielders et al.   HUMAN MUTATION

Probing Cellular Processes with Oligo-Mediated Recombination and Using the Knowledge Gained to Optimize Recombineering

(2011) James A. Sawitzke et al.   JOURNAL OF MOLECULAR BIOLOGY

Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides

(2011) Marleen Dekker et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion

(2011) H. H. Wang et al.   NUCLEIC ACIDS RESEARCH

Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

(2011) Alan J. Herr et al.   PLoS Genetics

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved

(2011) Izumi Miyabe et al.   PLoS Genetics

Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application

(2010) M Aarts et al.   GENE THERAPY

Oxidized purine nucleotides, genome instability and neurodegeneration

(2010) Ilenia Ventura et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mutagenicity of oxidized DNA precursors in living cells: Roles of nucleotide pool sanitization and DNA repair enzymes, and translesion synthesis DNA polymerases

(2010) Hiroyuki Kamiya   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damage

(2010) M. Aarts et al.   NUCLEIC ACIDS RESEARCH

Genome-wide model for the normal eukaryotic DNA replication fork

(2010) Andres A. Larrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PCNA function in the activation and strand direction of MutL  endonuclease in mismatch repair

(2010) A. Pluciennik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New generation of loxP-mutated deletion cassettes for the genetic manipulation of yeast natural isolates

(2010) Zorana Carter et al.   YEAST

Mismatch Repair–Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase ε

(2010) Anna Aksenova et al.   PLoS Genetics

Specific targeted gene repair using single-stranded DNA oligonucleotides at an endogenous locus in mammalian cells uses homologous recombination

(2009) Jennifer McLachlan et al.   DNA REPAIR

Use of internally nuclease-protected single-strand DNA oligonucleotides and silencing of the mismatch repair protein, MSH2, enhances the replication of corrected cells following gene editing

(2009) Ioannis Papaioannou et al.   JOURNAL OF GENE MEDICINE

Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers

(2009) Laura Baglietto et al.   JNCI-Journal of the National Cancer Institute

DNA polymerases at the eukaryotic fork—20 years later

(2009) Youri I. Pavlov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

DNA polymerase   and   proofreading suppress discrete mutator and cancer phenotypes in mice

(2009) T. M. Albertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair

(2009) F. A. Kadyrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient deletion method for the engineering of plasmid DNA with single-stranded oligonucleotides

(2008) Lin-Yu Lu et al.   BIOTECHNIQUES

Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases

(2008) Petter Angell Olsen et al.   DNA REPAIR

Division of Labor at the Eukaryotic Replication Fork

(2008) Stephanie A. Nick McElhinny et al.   MOLECULAR CELL

Oligonucleotide-Mediated Gene Targeting in Human Hepatocytes: Implications of Mismatch Repair

(2008) Olga Igoucheva et al.   OLIGONUCLEOTIDES

Dividing the workload at a eukaryotic replication fork

(2008) Thomas A. Kunkel et al.   TRENDS IN CELL BIOLOGY