Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

FastRFunctions for Robust Correlations and Hierarchical Clustering

(2015) Peter Langfelder et al.   Journal of Statistical Software

Genomic Profiling of Hepatocellular Adenomas Reveals Recurrent FRK-Activating Mutations and the Mechanisms of Malignant Transformation

(2014) Camilla Pilati et al.   CANCER CELL

UHRF1 Overexpression Drives DNA Hypomethylation and Hepatocellular Carcinoma

(2014) Raksha Mudbhary et al.   CANCER CELL

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

(2013) Erich Gulbins et al.   NATURE MEDICINE

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine Tumors

(2013) N. S. Jahchan et al.   Cancer Discovery

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma

(2012) S Hagiwara et al.   BRITISH JOURNAL OF CANCER

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

(2012) Enrico Moro et al.   DEVELOPMENTAL BIOLOGY

A Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches

(2012) Ekihiro Seki et al.   GASTROENTEROLOGY

The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver

(2012) Chunyue Yin et al.   HEPATOLOGY

Atypical hepatocellular adenoma–like neoplasms with β-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas

(2012) Kimberley J. Evason et al.   HUMAN PATHOLOGY

MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition

(2012) Dai Horiuchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

(2012) Wing-Kin Sung et al.   NATURE GENETICS

Zebrafish Models for Cancer

(2011) Shu Liu et al.   Annual Review of Pathology-Mechanisms of Disease

The effect of tricyclic antidepressants on cutaneous melanoma cell lines and primary cell cultures

(2011) Katharine A. Parker et al.   ANTI-CANCER DRUGS

Strategies for aggregating gene expression data: The collapseRows R function

(2011) Jeremy A Miller et al.   BMC BIOINFORMATICS

Systemic Therapy in Hepatocellular Carcinoma

(2011) Stephen H. Wrzesinski et al.   Clinics in Liver Disease

Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b

(2011) Isla D. Cheung et al.   DEVELOPMENTAL BIOLOGY

Role of DNA flow cytometry and immunocytochemical analysis in diagnosis of malignant effusions

(2011) Reetu Kundu et al.   DIAGNOSTIC CYTOPATHOLOGY

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma

(2011) Edmund Kwok-Kwan Tung et al.   LIVER INTERNATIONAL

The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence

(2011) X. Mao et al.   MOLECULAR PHARMACOLOGY

5-HT2B receptors are required for serotonin-selective antidepressant actions

(2011) S L Diaz et al.   MOLECULAR PSYCHIATRY

Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

(2011) John R. Lamb et al.   PLoS One

Revisiting the Pathology of Resected Benign Hepatocellular Nodules Using New Immunohistochemical Markers

(2011) Paulette Bioulac-Sage et al.   SEMINARS IN LIVER DISEASE

Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs

(2010) Mario David Cordero et al.   ANTI-CANCER DRUGS

A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription

(2010) K. Ewan et al.   CANCER RESEARCH

Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant β-catenin

(2010) Kari N. Nejak-Bowen et al.   HEPATOLOGY

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma

(2010) Julja Burchard et al.   Molecular Systems Biology

Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad

(2010) Kari Nichole Nejak-Bowen et al.   SEMINARS IN CANCER BIOLOGY

Pathogenesis of hepatocellular carcinoma and molecular therapies

(2009) Beatriz Mínguez et al.   CURRENT OPINION IN GASTROENTEROLOGY

Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma

(2009) Hiromitsu Nagata et al.   HEPATOLOGY

The Links between Transcription,  -catenin/JNK Signaling, and Carcinogenesis

(2009) A. Saadeddin et al.   MOLECULAR CANCER RESEARCH

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Distinct populations of quiescent and proliferative pancreatic  -cells identified by HOTcre mediated labeling

(2009) D. Hesselson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

(2008) D. Y. Chiang et al.   CANCER RESEARCH

Regionally Specific Regulation of ERK MAP Kinase in a Model of Antidepressant-Sensitive Chronic Depression

(2007) Shannon L. Gourley et al.   BIOLOGICAL PSYCHIATRY