Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy

DrosophilaSpag Is the Homolog of RNA Polymerase II-associated Protein 3 (RPAP3) and Recruits the Heat Shock Proteins 70 and 90 (Hsp70 and Hsp90) during the Assembly of Cellular Machineries

(2014) Nour El Houda Benbahouche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

(2013) Erik S. Musiek et al.   JOURNAL OF CLINICAL INVESTIGATION

The Transcription Factor Mef2 Links the Drosophila Core Clock to Fas2, Neuronal Morphology, and Circadian Behavior

(2013) Anna Sivachenko et al.   NEURON

Noncanonical FK506-Binding Protein BDBT Binds DBT to Enhance Its Circadian Function and Forms Foci at Night

(2013) Jin-Yuan Fan et al.   NEURON

ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals

(2013) Teruya Tamaru et al.   PLoS One

Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations

(2012) Wenyu Luo et al.   AGING CELL

RPAP3 splicing variant isoform 1 interacts with PIH1D1 to compose R2TP complex for cell survival

(2012) Miki Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of Aging on the Molecular Circadian Oscillations inDrosophila

(2012) Kuntol Rakshit et al.   CHRONOBIOLOGY INTERNATIONAL

Pigment-Dispersing Factor Is Involved in Age-Dependent Rhythm Changes in Drosophila melanogaster

(2012) Yujiro Umezaki et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian rhythms in the morphology of neurons in Drosophila

(2011) Kerstin I. Mehnert et al.   CELL AND TISSUE RESEARCH

Circadian Clock Gene Expression in Brain Regions of Alzheimer ’s Disease Patients and Control Subjects

(2011) Nicolas Cermakian et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Loss of circadian clock accelerates aging in neurodegeneration-prone mutants

(2011) Natraj Krishnan et al.   NEUROBIOLOGY OF DISEASE

The Clock Input to the First Optic Neuropil of Drosophila melanogaster Expressing Neuronal Circadian Plasticity

(2011) Milena Damulewicz et al.   PLoS One

Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 1. Circadian changes

(2010) Roxanne Sterniczuk et al.   BRAIN RESEARCH

A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila

(2010) S. Zhang et al.   GENETICS

The Pih1-Tah1 Cochaperone Complex Inhibits Hsp90 Molecular Chaperone ATPase Activity

(2010) Kelvin Eckert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axonal Degeneration Is Regulated by the Apoptotic Machinery or a NAD+-Sensitive Pathway in Insects and Mammals

(2010) Z. Schoenmann et al.   JOURNAL OF NEUROSCIENCE

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

(2010) Vikram Khurana et al.   PLoS Genetics

Transgenic Drosophila models of Alzheimer’s disease and tauopathies

(2009) Kanae Iijima-Ando et al.   Brain Structure & Function

Neuronal caspase-3 signaling: not only cell death

(2009) M D'Amelio et al.   CELL DEATH AND DIFFERENTIATION

PDF receptor expression reveals direct interactions between circadian oscillators indrosophila

(2009) Seol Hee Im et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells

(2009) Chunhui Li et al.   JOURNAL OF NEUROCHEMISTRY

Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains

(2008) Yuki Itsuki et al.   FEBS LETTERS

Drosophila and Vertebrate Casein Kinase I  Exhibits Evolutionary Conservation of Circadian Function

(2008) J.-Y. Fan et al.   GENETICS

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Circadian Remodeling of Neuronal Circuits Involved in Rhythmic Behavior

(2008) María Paz Fernández et al.   PLOS BIOLOGY