Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Zygotic Genome Activation During the Maternal-to-Zygotic Transition

(2014) Miler T. Lee et al.   Annual Review of Cell and Developmental Biology

Supernumerary subunits NDUFA3, NDUFA5 and NDUFA12 are required for the formation of the extramembrane arm of human mitochondrial complex I

(2014) Malgorzata Rak et al.   FEBS LETTERS

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

(2014) D. M. Messerschmidt et al.   GENES & DEVELOPMENT

Divergent reprogramming routes lead to alternative stem-cell states

(2014) Peter D. Tonge et al.   NATURE

Comparative analysis of the transcriptome across distant species

(2014) Mark B. Gerstein et al.   NATURE

Determinants of expression variability

(2014) Elfalem Y. Alemu et al.   NUCLEIC ACIDS RESEARCH

Parameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles

(2014) Sameer S. Bajikar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of the transcriptional landscapes between human and mouse tissues

(2014) Shin Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro

(2014) Dmitry A. Ovchinnikov et al.   Stem Cell Research

Gene Expression Variability as a Unifying Element of the Pluripotency Network

(2014) Elizabeth A. Mason et al.   Stem Cell Reports

Rho-Associated Kinase Activity Is Required for Proper Morphogenesis of the Inner Cell Mass in the Mouse Blastocyst1

(2013) Arlene May A. Laeno et al.   BIOLOGY OF REPRODUCTION

c-Met-Dependent Multipotent Labyrinth Trophoblast Progenitors Establish Placental Exchange Interface

(2013) Masaya Ueno et al.   DEVELOPMENTAL CELL

Deletions of recessive disease genes: CNV contribution to carrier states and disease-causing alleles

(2013) P. M. Boone et al.   GENOME RESEARCH

The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes

(2013) T. Soma-Nagae et al.   JOURNAL OF CELL SCIENCE

Novel Insights into the Role of Neurospora crassa NDUFAF2, an Evolutionarily Conserved Mitochondrial Complex I Assembly Factor

(2013) B. Pereira et al.   MOLECULAR AND CELLULAR BIOLOGY

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

(2013) Yusuke Ohnishi et al.   NATURE CELL BIOLOGY

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Human housekeeping genes, revisited

(2013) Eli Eisenberg et al.   TRENDS IN GENETICS

Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions

(2013) Jose Teles et al.   PLoS Computational Biology

From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes

(2013) Benjamin Georgi et al.   PLoS Genetics

Investigating transcriptional states at single-cell-resolution

(2012) Julia Tischler et al.   CURRENT OPINION IN BIOTECHNOLOGY

Assessment and treatment of repeated implantation failure (RIF)

(2012) Alex Simon et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Familial Focal Segmental Glomerulosclerosis (FSGS)-linked α-Actinin 4 (ACTN4) Protein Mutants Lose Ability to Activate Transcription by Nuclear Hormone Receptors

(2012) Simran Khurana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4

(2012) N Agarwal et al.   ONCOGENE

Using Gene Expression Noise to Understand Gene Regulation

(2012) B. Munsky et al.   SCIENCE

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

(2012) D. G. MacArthur et al.   SCIENCE

Genome-Wide Analysis of Human Preimplantation Aneuploidy

(2012) Nathan Treff   SEMINARS IN REPRODUCTIVE MEDICINE

Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology

(2012) James A. Briggs et al.   STEM CELLS

Interplay between gene expression noise and regulatory network architecture

(2012) Guilhem Chalancon et al.   TRENDS IN GENETICS

Transient Noise Amplification and Gene Expression Synchronization in a Bistable Mammalian Cell-Fate Switch

(2012) Santhosh Palani et al.   Cell Reports

Variability in the Generation of Induced Pluripotent Stem Cells: Importance for Disease Modeling

(2012) Alejandra M. Vitale et al.   Stem Cells Translational Medicine

Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development

(2011) R. Vassena et al.   DEVELOPMENT

Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo

(2011) Isabel M. González et al.   DEVELOPMENTAL BIOLOGY

Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo

(2011) Cuihong Lin et al.   FEBS LETTERS

Varying virulence: epigenetic control of expression noise and disease processes

(2011) Kathryn Miller-Jensen et al.   TRENDS IN BIOTECHNOLOGY

Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease

(2011) Jessica C. Mar et al.   PLoS Genetics

Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy

(2011) Nathan R. Treff et al.   PLoS Genetics

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

Epithelial Cell Adhesion Molecule Regulation Is Associated with the Maintenance of the Undifferentiated Phenotype of Human Embryonic Stem Cells

(2010) Tung-Ying Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells

(2010) Jinyoung Kim et al.   MATRIX BIOLOGY

Telomere lengths in human oocytes, cleavage stage embryos and blastocysts

(2010) S. Turner et al.   MOLECULAR HUMAN REPRODUCTION

Gene expression divergence recapitulates the developmental hourglass model

(2010) Alex T. Kalinka et al.   NATURE

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway

(2010) Emma McCullagh et al.   NATURE CELL BIOLOGY

Non-genetic heterogeneity from stochastic partitioning at cell division

(2010) Dann Huh et al.   NATURE GENETICS

Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress

(2010) Y. Hirota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-genetic heterogeneity of cells in development: more than just noise

(2009) S. Huang   DEVELOPMENT

Temporal switching and cell-to-cell variability in Ca2+ release activity in mammalian cells

(2009) Naotoshi Nakamura et al.   Molecular Systems Biology

Intrinsic variability of gene expression encoded in nucleosome positioning sequences

(2009) Jung Kyoon Choi et al.   NATURE GENETICS

Abnormal Placental Development and Early Embryonic Lethality in EpCAM-Null Mice

(2009) Keisuke Nagao et al.   PLoS One

Characterization of Epithelial Cell Adhesion Molecule as a Surface Marker on Undifferentiated Human Embryonic Stem Cells

(2009) Valerie Y. Ng et al.   STEM CELLS

Identification of Human Embryonic Stem Cell Surface Markers by Combined Membrane-Polysome Translation State Array Analysis and Immunotranscriptional Profiling

(2009) Gabriel Kolle et al.   STEM CELLS

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

Identification of human haploinsufficient genes and their genomic proximity to segmental duplications

(2008) Vinh T Dang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Regulatory networks define phenotypic classes of human stem cell lines

(2008) Franz-Josef Müller et al.   NATURE

Stochasticity and Cell Fate

(2008) R. Losick et al.   SCIENCE