Activation of Autophagy Rescues Amiodarone-Induced Apoptosis of Lung Epithelial Cells and Pulmonary Toxicity in Rats

Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury

(2013) Yu-Ting Yen et al.   SURGERY

Autophagy Is a Cell Self-Protective Mechanism Against Arsenic-Induced Cell Transformation

(2012) Tao Zhang et al.   TOXICOLOGICAL SCIENCES

Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis

(2011) Basant A. Abdulrahman et al.   Autophagy

Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration

(2011) Gaetano Serviddio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

(2011) Hong-Min Ni et al.   HEPATOLOGY

Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation

(2011) In Young Kim et al.   NEURO-ONCOLOGY

Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line

(2011) Irmgard Paris et al.   TOXICOLOGICAL SCIENCES

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR regulates autophagy-associated genes downstream of p73

(2009) Jennifer M. Rosenbluth et al.   Autophagy

Intracellular sequestration of amiodarone: role of vacuolar ATPase and macroautophagic transition of the resulting vacuolar cytopathology

(2009) G Morissette et al.   BRITISH JOURNAL OF PHARMACOLOGY

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy

(2009) Y. Kamada et al.   MOLECULAR AND CELLULAR BIOLOGY

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells

(2009) Hongyu Zhang et al.   TOXICOLOGICAL SCIENCES

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells

(2008) Adrian C. Nicolescu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY