JAK/STAT Pathway Plays a Critical Role in the Proinflammatory Gene Expression and Apoptosis of RAW264.7 Cells Induced by Trichothecenes as DON and T-2 Toxin

T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not aryl hydrocarbon receptor-dependent interleukin-8 secretion in the human intestinal epithelial cell line Caco-2

(2011) Pierre Kruber et al.   TOXICOLOGY

Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats

(2011) Awais Ihsan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance

(2010) James J. Pestka   ARCHIVES OF TOXICOLOGY

Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: Prevention of NF-κB nuclear localization and down regulation of NF-κB and Cyclo-Oxygenase – 2 expression

(2010) Rajashree Krishnaswamy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox

(2010) Xu Wang et al.   TOXICOLOGY

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

(2009) Lobelia Samavati et al.   MOLECULAR IMMUNOLOGY

Induction of Suppressors of Cytokine Signaling by the Trichothecene Deoxynivalenol in the Mouse

(2009) Chidozie J. Amuzie et al.   TOXICOLOGICAL SCIENCES

Suppression of Insulin-Like Growth Factor Acid-Labile Subunit Expression—A Novel Mechanism for Deoxynivalenol-Induced Growth Retardation

(2009) Chidozie J. Amuzie et al.   TOXICOLOGICAL SCIENCES

HuR/ELAVL1 RNA binding protein modulates interleukin-8 induction by muco-active ribotoxin deoxynivalenol

(2009) Hye Jin Choi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages

(2009) Stefania Marzocco et al.   TOXICOLOGY LETTERS

Mechanisms of deoxynivalenol-induced gene expression and apoptosis

(2008) J.J. Pestka   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Tissue distribution and proinflammatory cytokine gene expression following acute oral exposure to deoxynivalenol: Comparison of weanling and adult mice

(2008) James J. Pestka et al.   FOOD AND CHEMICAL TOXICOLOGY

Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level

(2007) Hyuck Kim et al.   CELLULAR SIGNALLING

Ribotoxic mycotoxin deoxynivalenol induces G2/M cell cycle arrest via p21Cip/WAF1 mRNA stabilization in human epithelial cells

(2007) Hyun Yang et al.   TOXICOLOGY