Mechanism of Inhibition of the ATPase Domain of Human Topoisomerase IIα by 1,4-Benzoquinone, 1,2-Naphthoquinone, 1,4-Naphthoquinone, and 9,10-Phenanthroquinone

Emodin Triggers DNA Double-Strand Breaks by Stabilizing Topoisomerase II-DNA Cleavage Complexes and by Inhibiting ATP Hydrolysis of Topoisomerase II

(2010) Yan Li et al.   TOXICOLOGICAL SCIENCES

Topoisomerase II inhibition by the bioactivated benzene metabolite hydroquinone involves multiple mechanisms

(2009) Scott Mondrala et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Electrophilic and redox properties of diesel exhaust particles

(2009) Masaru Shinyashiki et al.   ENVIRONMENTAL RESEARCH

Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition

(2008) Yu-Jun Cai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Coupling between ATP Binding and DNA Cleavage by DNA Topoisomerase II

(2008) Felix Mueller-Planitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of DNA double-strand breaks and γH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone

(2008) Daniel J. Smart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites

(2008) Alok Kumar Pandey et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells

(2008) Aida Muslimovic et al.   Nature Protocols

9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae

(2007) Chester E. Rodriguez et al.   TOXICOLOGY IN VITRO