Aryl Hydrocarbon Receptor (AhR) Regulates Silica-Induced Inflammation But Not Fibrosis

AhR deficiency impairs expression of LPS-induced inflammatory genes in mice

(2011) Dalei Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

(2011) Lucie Stejskalova et al.   CURRENT DRUG METABOLISM

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

External influences on the immune system via activation of the aryl hydrocarbon receptor

(2011) Brigitta Stockinger et al.   SEMINARS IN IMMUNOLOGY

Dioxin and immune regulation

(2010) Nikki B. Marshall et al.   Annals of the New York Academy of Sciences

IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis

(2010) Shambhoo Sharan Tripathi et al.   ARCHIVES OF TOXICOLOGY

Inflammasome Inhibition as a Pathogenic Stealth Mechanism

(2010) Debra J. Taxman et al.   Cell Host & Microbe

The aryl hydrocarbon receptor: fine-tuning the immune-response

(2010) Marc Veldhoen et al.   CURRENT OPINION IN IMMUNOLOGY

γδ T cells protect against lung fibrosis via IL-22

(2010) Philip L. Simonian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17A-Producing    T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis

(2010) S. Lo Re et al.   JOURNAL OF IMMUNOLOGY

Innate immune processes are sufficient for driving silicosis in mice

(2010) Celine A. Beamer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuli

(2010) Yoshiaki FUJII-KURIYAMA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aryl Hydrocarbon Receptor Activation Reduces Dendritic Cell Function during Influenza Virus Infection

(2010) Guang-Bi Jin et al.   TOXICOLOGICAL SCIENCES

Effects of TCDD on the Fate of Naive Dendritic Cells

(2010) Jaishree Bankoti et al.   TOXICOLOGICAL SCIENCES

Functional and phenotypic effects of AhR activation in inflammatory dendritic cells

(2010) Jaishree Bankoti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

3,3′-Diindolylmethane attenuates experimental arthritis and osteoclastogenesis

(2009) Lei Dong et al.   BIOCHEMICAL PHARMACOLOGY

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: TNF-  Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

(2009) L. Franchi et al.   JOURNAL OF IMMUNOLOGY

Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice

(2009) B. Jux et al.   JOURNAL OF IMMUNOLOGY

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

(2009) H. Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Critical Role of MARCO in Crystalline Silica–Induced Pulmonary Inflammation

(2009) Sheetal A. Thakur et al.   TOXICOLOGICAL SCIENCES

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

(2009) Stacey L. Demento et al.   VACCINE

Th1/Th2 Immune Response in Lung Fibroblasts in Interstitial Lung Disease

(2008) Atsushi Sumida et al.   ARCHIVES OF MEDICAL RESEARCH

AHR-mediated immunomodulation: The role of altered gene transcription

(2008) Nancy I. Kerkvliet   BIOCHEMICAL PHARMACOLOGY

Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

(2008) E. Hauben et al.   BLOOD

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

(2008) Luigi Franchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Silica binding and toxicity in alveolar macrophages

(2007) Raymond F. Hamilton et al.   FREE RADICAL BIOLOGY AND MEDICINE