Selective Phthalate Activation of Naturally Occurring Human Constitutive Androstane Receptor Splice Variants and the Pregnane X Receptor

Human Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogens Phenobarbital and Chlordane In Vivo

(2010) Jillian Ross et al.   TOXICOLOGICAL SCIENCES

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Urinary Metabolites of Di(2-ethylhexyl) Phthalate Are Associated With Decreased Steroid Hormone Levels in Adult Men

(2009) J. D. Meeker et al.   JOURNAL OF ANDROLOGY

The Constitutive Androstane Receptor Is an Anti-obesity Nuclear Receptor That Improves Insulin Sensitivity

(2009) Jie Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

A Single Amino Acid Controls the Functional Switch of Human Constitutive Androstane Receptor (CAR) 1 to the Xenobiotic-Sensitive Splicing Variant CAR3

(2009) T. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Di(2-ethylhexyl) phthalate Is a Highly Potent Agonist for the Human Constitutive Androstane Receptor Splice Variant CAR2

(2009) J. G. DeKeyser et al.   MOLECULAR PHARMACOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

(2009) B. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Roles of Nuclear Receptors CAR and PXR in Hepatic Energy Metabolism

(2008) Yoshihiro Konno et al.   Drug Metabolism and Pharmacokinetics

Phthalates: metabolism and exposure

(2008) Matthias Wittassek et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice

(2008) David Masson et al.   JOURNAL OF LIPID RESEARCH

Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures

(2008) Katy M.O. Goyak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY