Tracking Human Contact Allergens: From Mass Spectrometric Identification of Peptide-Bound Reactive Small Chemicals to Chemical-Specific Naive Human T-Cell Priming

T regulatory cells in contact hypersensitivity

(2009) Andrea Cavani   Current Opinion in Allergy and Clinical Immunology

Human naive and memory CD4+T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

(2009) Rebekka Geiger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics

(2009) C. Pickard et al.   JOURNAL OF IMMUNOLOGY

Oxidation of Cell Surface Thiol Groups by Contact Sensitizers Triggers the Maturation of Dendritic Cells

(2009) Saori Kagatani et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Characterization of p-Phenylenediamine–Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein

(2009) Claire Jenkinson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: Possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate

(2009) Morihiko Hirota et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Reactivity Profiling: Covalent Modification of Single Nucleophile Peptides for Skin Sensitization Risk Assessment

(2009) Maja Aleksic et al.   TOXICOLOGICAL SCIENCES

Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1

(2009) Rym Megherbi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of changes of cell-surface thiols as a new biomarker for in vitro sensitization test

(2009) Mie Suzuki et al.   TOXICOLOGY IN VITRO

Sensitization to p-amino aromatic compounds: Study of the covalent binding of 2,5-dimethyl-p-benzoquinonediimine to a model peptide by electrospray ionization tandem mass spectrometry

(2008) Joan Eilstein et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Depletion of Human Peripheral Blood Lymphocytes in CD25+ Cells Allows for the Sensitive In Vitro Screening of Contact Allergens

(2008) Marc Vocanson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LC-MS–Based Characterization of the Peptide Reactivity of Chemicals to Improve the In Vitro Prediction of the Skin Sensitization Potential

(2008) Andreas Natsch et al.   TOXICOLOGICAL SCIENCES

Mass spectrometric identification of covalent adducts of the skin allergen 2,4-dinitro-1-chlorobenzene and model skin proteins

(2008) Maja Aleksic et al.   TOXICOLOGY IN VITRO

Allergic Contact Dermatitis––Formation, Structural Requirements, and Reactivity of Skin Sensitizers

(2007) Ann-Therese Karlberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY