Article
Agronomy
Shauni Windle, Scott McMurry, Richard Brain, Jonathan Maul, Jeffrey Wolf, Jason Belden
Summary: This study examined the effects of exposure to atrazine and estradiol on the development of Blanchard's cricket frog larvae. The results showed that atrazine did not significantly affect the survival, growth, or reproductive development of the frogs, while estradiol exposure did have some effects on male frogs' oviduct development. Overall, the study suggests that Blanchard's cricket frogs may be less sensitive to these endocrine-disrupting compounds compared to other species.
PEST MANAGEMENT SCIENCE
(2022)
Article
Neurosciences
Erin E. Maher, Paula F. Overby, Amanda H. Bull, Joshua S. Beckmann, Jonna M. Leyrer-Jackson, Stephanie Koebele, Heather A. Bimonte-Nelson, Cassandra D. Gipson
Summary: This study found that women have more difficulty quitting smoking and currently available treatments are less effective for women. Fluctuations in ovarian hormones across the menstrual cycle can affect craving and smoking relapse propensity. Natural and synthetic estrogens play a critical role in mediating the neurobehavioral effects of nicotine.
Article
Environmental Sciences
Yingxiao Ma, Feng Yan, Lili An, Wendi Shen, Tingting Tang, Zihao Li, Ruihua Dai
Summary: This study investigated the physiological and molecular responses of Microcystis aeruginosa to ethinyl estradiol (EE2) exposure. The results showed that low levels of EE2 enhanced algal cell growth, while high levels inhibited it. EE2 also promoted the production of microcystins and caused oxidative damage to the algal cells. Furthermore, EE2 disrupted various metabolic and synthetic processes in the cells.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Obstetrics & Gynecology
Aaron Lazorwitz, Morgan Pena, Jeanelle Sheeder, Stephanie Teal
Summary: The pharmacokinetic interaction between topiramate and etonogestrel in contraceptive implant users resulted in decreased serum etonogestrel concentrations, potentially impacting contraceptive efficacy.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Endocrinology & Metabolism
Ioanna Katsiadaki, Tamar I. Schwarz, Alex R. O. Cousins, Alexander P. Scott
Summary: Mussels can readily absorb mammalian sex steroids, storing some in the form of fatty acid esters, while the metabolism of ethinyl-estradiol and cortisol differs from that of estradiol and other steroids.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Environmental Sciences
Shauni Windle, Scott McMurry, Richard Brain, Jonathan Maul, Daniel B. Pickford, Jeffrey Wolf, Jason Belden
Summary: A developmental toxicity testing design was evaluated on outdoor enclosures for larval and post-metamorphic Blanchard's cricket frogs, showing that exposure to 17 beta-estradiol did not significantly influence development, but the highest E2 treatment resulted in a 4.5-fold increase in oviduct development in males and half the development in females compared to the control group. Despite no treatment-related effects, significant variations in body mass and SVL were observed within enclosures.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemical Research Methods
Loredana Annunziata, Pierina Visciano, Maria Rosaria De Massis, Maria Schirone, Maria Novella Colagrande, Guido Campana, Giacomo Migliorati
Summary: The aim of this study was to detect unauthorized substances in poultry meat samples using specific enzyme-linked immunosorbent assay kits. The validation showed that the ELISA kits could be used for screening large numbers of samples.
DRUG TESTING AND ANALYSIS
(2021)
Article
Neurosciences
Stephanie V. Koebele, Mallori L. Poisson, Justin M. Palmer, Claire Berns-Leone, Steven N. Northup-Smith, Veronica L. Pena, Isabel M. Strouse, Haidyn L. Bulen, Shruti Patel, Corissa Croft, Heather A. Bimonte-Nelson
Summary: Oral contraceptives and hormone therapies use progestogen to prevent ovulation and reduce cancer risk. This study investigates the impact of drospirenone on spatial memory and anxiety-like behavior, and explores the effects of adding ethinyl estradiol. Results show that drospirenone benefits spatial memory, but the addition of ethinyl estradiol reverses this effect.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Engineering, Chemical
Ming Liu, Mei Lin, Gary Owens, Zuliang Chen
Summary: Manganese tetroxide nanomaterials prepared by green tea extract were found to effectively catalyze the degradation of E3 and EE2 through PDS. Various analyses and studies revealed the catalytic mechanism and formation pathways of degradation products.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Jeffrey T. Jensen, David F. Archer, Carolyn L. Westhoff, Anita L. Nelson, Shelli Graham, Brian Bernick
Summary: This study evaluated the satisfaction of women who had recently used a monthly contraceptive ring or contraceptive pills with a segesterone acetate and ethinyl estradiol contraceptive vaginal system. The results showed high satisfaction with the vaginal system, and most women liked it as much or better than any previous contraceptive method. The ease of use and one-year duration were the most liked features, while ring insertion and feeling it coming out were the most disliked features. The majority of participants had no concerns about using the system for a year and had recommended it to others.
JOURNAL OF WOMENS HEALTH
(2023)
Article
Medicine, Research & Experimental
Ganesh Cherala, Cara Nelson, Ying Guo, Anubhav Mathur, Thomas Tarnowski, Ahmed A. Othman
Summary: This study evaluated the pharmacokinetic interactions between Tirabrutinib and the oral contraceptive levonorgestrel/ethinyl estradiol. The results showed that Tirabrutinib did not alter the exposure of levonorgestrel/ethinyl estradiol, indicating that it can be used as a contraception method.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2022)
Review
Endocrinology & Metabolism
Sarah Kheloui, Andra Smith, Nafissa Ismail
Summary: Combined oral contraceptives are widely used among females, but their effects on the gut-brain axis and their impact on the developing adolescent brain are not well-studied. This article reviews evidence from animal and human studies on the effects of combined oral contraceptives on the brain and the gut microbiota during adolescence, highlighting the importance of further research in this field.
FRONTIERS IN NEUROENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Kahina Chabi, Lekha Sleno
Summary: This study demonstrates the usefulness of isotope-labeled compounds in detecting and elucidating the structures of metabolites and trapped adducts of three estrogen analogs using an untargeted LC-MS/MS workflow. The use of isotopic labeling was crucial in confirming many metabolites and adduct structures, as well as removing endogenous interferences.
Article
Cell Biology
B. O. Jeminiwa, R. C. Knight, K. L. Abbot, S. R. Pondugula, B. T. Akingbemi
Summary: Environmental chemicals can disrupt the endocrine axis and are classified as endocrine disrupting chemicals. Some commonly used consumer product chemicals (such as Bisphenol S and 17 alpha-ethinyl estradiol) may have adverse effects on the population. In animal models, exposure to individual chemicals or combinations of multiple chemicals can lead to disturbances in sex steroid secretion.
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2021)
Article
Electrochemistry
Zepeng Qian, Shashi Lalvani, Lei L. Kerr
Summary: A study utilized a carbon-based screen-printed disposable electrode to detect synthetic estradiol residue in water bodies. The analysis showed an irreversible oxidation peak involving adsorption of EE2 on the electrode surface, with a linear relationship between peak current and concentration. Parameters such as rate constant, adsorption capacity, repeatability, sensitivity, and detection limits were also provided.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)