Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations

Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans

(2014) Z. Y. Tam et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging

(2014) A. Kowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

(2014) Piero Dalle Pezze et al.   PLoS Computational Biology

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

(2013) Debapriya Dutta et al.   Autophagy

Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance

(2013) Zhi Yang Tam et al.   PLoS One

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Optimal Dynamics for Quality Control in Spatially Distributed Mitochondrial Networks

(2013) Pinkesh K. Patel et al.   PLoS Computational Biology

Is mitochondrial DNA turnover slower than commonly assumed?

(2012) Suresh Kumar Poovathingal et al.   BIOGERONTOLOGY

Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing

(2012) Jan Gruber et al.   BIOTECHNOLOGY ADVANCES

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse

(2012) Lloye M. Dillon et al.   HUMAN MOLECULAR GENETICS

Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans

(2012) Amanda S. Bess et al.   NUCLEIC ACIDS RESEARCH

Relationship between Human Aging Muscle and Oxidative System Pathway

(2012) Enrico Doria et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism

(2012) D. Narendra et al.   Cold Spring Harbor Perspectives in Biology

Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

(2012) Marc Thilo Figge et al.   PLoS Computational Biology

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition

(2011) Robert W. Gilkerson et al.   HUMAN MOLECULAR GENETICS

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

(2011) Liliane Glauser et al.   JOURNAL OF NEUROCHEMISTRY

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Therapeutic prospects for mitochondrial disease

(2010) Eric A. Schon et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial DNA mutations and ageing

(2009) Laura C. Greaves et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Frequency and Selectivity of Mitochondrial Fusion Are Key to Its Quality Maintenance Function

(2009) Pradeep K. Mouli et al.   BIOPHYSICAL JOURNAL

Mitochondrial ‘kiss-and-run’: interplay between mitochondrial motility and fusion–fission dynamics

(2009) Xingguo Liu et al.   EMBO JOURNAL

Stochastically determined directed movement explains the dominant small-scale mitochondrial movements within non-neuronal tissue culture cells

(2009) Christopher D. Saunter et al.   FEBS LETTERS

Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA

(2009) Adriana Malena et al.   HUMAN MOLECULAR GENETICS

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Mitochondrial functional complementation in mitochondrial DNA-based diseases

(2009) Kazuto Nakada et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Number matters: control of mammalian mitochondrial DNA copy number

(2009) Laura L. Clay Montier et al.   Journal of Genetics and Genomics

Stochastic approaches in systems biology

(2009) Mukhtar Ullah et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico

(2009) Suresh Kumar Poovathingal et al.   PLoS Computational Biology

Mitochondrial turnover in liver is fastin vivoand is accelerated by dietary restriction: application of a simple dynamic model

(2008) Satomi Miwa et al.   AGING CELL

Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view

(2008) Gilad Twig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

(2008) Filip Simunovic et al.   BRAIN

Mitochondrial fission and fusion dynamics: the long and short of it

(2008) S B Berman et al.   CELL DEATH AND DIFFERENTIATION

RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype

(2008) Tina Wenz et al.   Cell Metabolism

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

GUI–HDMR – A software tool for global sensitivity analysis of complex models

(2008) T. Ziehn et al.   ENVIRONMENTAL MODELLING & SOFTWARE

Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons

(2008) Hirokazu Fukui et al.   HUMAN MOLECULAR GENETICS

Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation

(2008) Robert W. Gilkerson et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Whole-cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution

(2008) Bo Huang et al.   NATURE METHODS