Journal
TOXICOLOGIC PATHOLOGY
Volume 43, Issue 2, Pages 257-266Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0192623314538344
Keywords
Gottingen minipigs; histopathology; spontaneous lesion; background data
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The Gottingen minipig is gaining increasing popularity as a nonrodent species in nonclinical testing. The Gottingen minipig is easy to handle; has many anatomical and physiological similarities to man; and causes fewer ethical concerns than usage of the traditional nonrodent species, nonhuman primates, and dogs. The increasing usage of the Gottingen minipig has raised the need of appropriate background data. This article summarizes the background pathology of 835 untreated control Gottingen minipigs of both sexes used at CiToxLAB Scantox A/S during the period of 1995 to 2007.
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