Preclinical Toxicity of AZD7969

Comparison of Computerized Image Analysis with Traditional Semiquantitative Scoring of Perls’ Prussian Blue Stained Hepatic Iron Deposition

(2013) A. Peter Hall et al.   TOXICOLOGIC PATHOLOGY

Human stem cell osteoblastogenesis mediated by novel glycogen synthase kinase 3 inhibitors induces bone formation and a unique bone turnover biomarker profile in rats

(2013) Peter S. Gilmour et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Upregulation of Glycogen Synthase Kinase 3β in Human Colorectal Adenocarcinomas Correlates With Accumulation of CTNNB1

(2012) Hanlin L. Wang et al.   Clinical Colorectal Cancer

GSK3b-inhibitor lithium chloride enhances activation of Wnt canonical signaling and osteoblast differentiation on hydrophilic titanium surfaces

(2012) C. Galli et al.   CLINICAL ORAL IMPLANTS RESEARCH

Glycogen Synthase Kinase-3β, NF-κB Signaling, and Tumorigenesis of Human Osteosarcoma

(2012) Qing-Lian Tang et al.   JNCI-Journal of the National Cancer Institute

Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells

(2012) Soung-Hoon Lee et al.   PLoS One

Glycogen Synthase Kinase-3 Inhibition Promotes Proliferation and Neuronal Differentiation of Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors

(2012) Fereshteh Esfandiari et al.   STEM CELLS AND DEVELOPMENT

GSK-3 inhibition by an orally active small molecule increases bone mass in rats

(2011) Richard Marsell et al.   BONE

Glycogen synthase kinase-3α/β inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage

(2010) Alessandra Gambardella et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress

(2010) K. Hailemariam et al.   JOURNAL OF CELL SCIENCE

Incisor Degeneration in Rats Induced by Vascular Endothelial Growth Factor/Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibition

(2010) Anthony M. Fletcher et al.   TOXICOLOGIC PATHOLOGY

The Role of Hepcidin in Iron Metabolism

(2009) Elizabeta Nemeth et al.   ACTA HAEMATOLOGICA

Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis1

(2009) Pradeep S. Tanwar et al.   BIOLOGY OF REPRODUCTION

Role for DYRK family kinases on regulation of apoptosis

(2008) Kiyotsugu Yoshida   BIOCHEMICAL PHARMACOLOGY

GSK-3β Targets Cdc25A for Ubiquitin-Mediated Proteolysis, and GSK-3β Inactivation Correlates with Cdc25A Overproduction in Human Cancers

(2008) Tiebang Kang et al.   CANCER CELL

GSK3β: A master switch and a promising target

(2008) Akanksha Kannoji et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Nonclinical Safety Evaluation of Sunitinib: A Potent Inhibitor of VEGF, PDGF, KIT, FLT3, and RET Receptors

(2008) Shem Patyna et al.   TOXICOLOGIC PATHOLOGY