Translation Strategy for the Qualification of Drug-induced Vascular Injury Biomarkers

Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis

(2012) Paul A Monach et al.   ANNALS OF THE RHEUMATIC DISEASES

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

(2012) J. C. Jennette et al.   ARTHRITIS AND RHEUMATISM

Endocan Is Upregulated on Tumor Vessels in Invasive Bladder Cancer Where It Mediates VEGF-A-Induced Angiogenesis

(2012) F. Roudnicky et al.   CANCER RESEARCH

Retrospective Analysis of Surgery Versus Endovascular Intervention in Takayasu Arteritis

(2012) David Saadoun et al.   CIRCULATION

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis

(2012) Paul A. Monach et al.   PLoS One

Prognostic factors in patients with hepatitis C virus infection and systemic vasculitis

(2011) Benjamin Terrier et al.   ARTHRITIS AND RHEUMATISM

Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis

(2011) Paul A. Monach et al.   ARTHRITIS AND RHEUMATISM

Endothelial vascular toxicity from chemotherapeutic agents: Preclinical evidence and clinical implications

(2011) Aspasia Soultati et al.   CANCER TREATMENT REVIEWS

A generic operational strategy to qualify translational safety biomarkers

(2011) Katja Matheis et al.   DRUG DISCOVERY TODAY

TGF-β and Restenosis Revisited: A Smad Link

(2011) Pasithorn A. Suwanabol et al.   JOURNAL OF SURGICAL RESEARCH

Taming the dragon: genomic biomarkers to individualize the treatment of cancer

(2011) Ian J Majewski et al.   NATURE MEDICINE

Phase II failures: 2008–2010

(2011) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

The productivity crisis in pharmaceutical R&D

(2011) Fabio Pammolli et al.   NATURE REVIEWS DRUG DISCOVERY

Prevalence and clinical significance of cryofibrinogenaemia in patients with renal disorders

(2011) B. Terrier et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Biomarkers of endothelial cell activation: Candidate markers for drug-induced vasculitis in patients or drug-induced vascular injury in animals

(2011) Jun Zhang et al.   VASCULAR PHARMACOLOGY

Pharmaceutical Innovation in the 21st Century: New Drug Approvals in the First Decade, 2000–2009

(2010) K I Kaitin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Biomarker-assisted diagnosis of acute aortic dissection: how far we have come and what to expect

(2010) Toru Suzuki et al.   CURRENT OPINION IN CARDIOLOGY

Early Events in Vascular Injury in the Rat Induced by the Phosphodiesterase IV Inhibitor SCH 351591

(2010) James L. Weaver et al.   TOXICOLOGIC PATHOLOGY

Primary Endothelial Damage Is the Mechanism of Cardiotoxicity of Tubulin-Binding Drugs

(2010) Igor Mikaelian et al.   TOXICOLOGICAL SCIENCES

Drug-induced vasculitis

(2009) Allan Wiik   CURRENT OPINION IN RHEUMATOLOGY

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

(2008) C. Urbich et al.   CARDIOVASCULAR RESEARCH

Endothelial microparticles in diseases

(2008) Gilles N. Chironi et al.   CELL AND TISSUE RESEARCH

Method validation of protein biomarkers in support of drug development or clinical diagnosis/prognosis☆

(2008) Jean W. Lee et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Histopathology of Vascular Injury in Sprague-Dawley Rats Treated with Phosphodiesterase IV Inhibitor SCH 351591 or SCH 534385

(2008) Jun Zhang et al.   TOXICOLOGIC PATHOLOGY

Cardiovascular toxicity of minoxidil in the marmoset

(2008) Gilles Hanton et al.   TOXICOLOGY LETTERS