Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network

Multi-scale modelling of the dynamics of cell colonies: insights into cell-adhesion forces and cancer invasion from in silico simulations

(2014) D. K. Schluter et al.   Journal of the Royal Society Interface

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip

(2013) T. Bornschlogl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Initial Cell Spreading Using Mechanistic Contact Formulations for a Deformable Cell Model

(2013) Tim Odenthal et al.   PLoS Computational Biology

Mathematical Modeling of Cancer Invasion: The Role of Membrane-Bound Matrix Metalloproteinases

(2013) Niall E. Deakin et al.   Frontiers in Oncology

Computational Modeling of Single-Cell Migration: The Leading Role of Extracellular Matrix Fibers

(2012) Daniela K. Schlüter et al.   BIOPHYSICAL JOURNAL

Integrating focal adhesion dynamics, cytoskeleton remodeling, and actin motor activity for predicting cell migration on 3D curved surfaces of the extracellular matrix

(2012) Min-Cheol Kim et al.   Integrative Biology

Cell Adhesion and Its Endocytic Regulation in Cell Migration during Neural Development and Cancer Metastasis

(2012) Takeshi Kawauchi   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modeling the influence of nucleus elasticity on cell invasion in fiber networks and microchannels

(2012) Marco Scianna et al.   JOURNAL OF THEORETICAL BIOLOGY

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Ensemble Analysis of Angiogenic Growth in Three-Dimensional Microfluidic Cell Cultures

(2012) Waleed A. Farahat et al.   PLoS One

Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies

(2012) Daisuke Hoshino et al.   PLoS Computational Biology

Criticality and isostaticity in fibre networks

(2011) Chase P. Broedersz et al.   Nature Physics

Mechanistic modeling of the effects of myoferlin on tumor cell invasion

(2011) M. C. Eisenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pericellular Conditions Regulate Extent of Cell-Mediated Compaction of Collagen Gels

(2010) Mark D. Stevenson et al.   BIOPHYSICAL JOURNAL

The micromechanics of three-dimensional collagen-I gels

(2010) Andrew M. Stein et al.   COMPLEXITY

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Filopodial focal complexes direct adhesion and force generation towards filopodia outgrowth

(2010) Bernd Hoffmann et al.   Cell Adhesion & Migration

Crosslinking of cell-derived 3D scaffolds up-regulates the stretching and unfolding of new extracellular matrix assembled by reseeded cells

(2009) Kristopher E. Kubow et al.   Integrative Biology

Demonstration of catch bonds between an integrin and its ligand

(2009) Fang Kong et al.   JOURNAL OF CELL BIOLOGY

Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia

(2009) R. Poincloux et al.   JOURNAL OF CELL SCIENCE

Strain-Induced Alignment in Collagen Gels

(2009) David Vader et al.   PLoS One

Molecular noise of capping protein binding induces macroscopic instability in filopodial dynamics

(2009) Pavel I. Zhuravlev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Image-based multiscale modeling predicts tissue-level and network-level fiber reorganization in stretched cell-compacted collagen gels

(2009) E. A. Sander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dependence of Invadopodia Function on Collagen Fiber Spacing and Cross-Linking: Computational Modeling and Experimental Evidence

(2008) Heiko Enderling et al.   BIOPHYSICAL JOURNAL

The Stochastic Dynamics of Filopodial Growth

(2008) Yueheng Lan et al.   BIOPHYSICAL JOURNAL

Catch-Bond Mechanism of Force-Enhanced Adhesion: Counterintuitive, Elusive, but … Widespread?

(2008) Evgeni V. Sokurenko et al.   Cell Host & Microbe

One step ahead: Role of filopodia in adhesion formation during cell migration of keratinocytes

(2008) Claudia Schäfer et al.   EXPERIMENTAL CELL RESEARCH

Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella

(2008) Maria Nemethova et al.   JOURNAL OF CELL BIOLOGY

Protrusion of a Virtual Model Lamellipodium by Actin Polymerization: A Coarse-Grained Langevin Dynamics Model

(2008) Junhwan Jeon et al.   JOURNAL OF STATISTICAL PHYSICS

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY

Limits of Filopodium Stability

(2008) Sander Pronk et al.   PHYSICAL REVIEW LETTERS

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

Mechanical Properties of Native and Cross-linked Type I Collagen Fibrils

(2007) Lanti Yang et al.   BIOPHYSICAL JOURNAL