Regulated CRISPR Modules Exploit a Dual Defense Strategy of Restriction and Abortive Infection in a Model of Prokaryote-Phage Coevolution

Association of CRISPR/Cas Evolution withVibrio parahaemolyticusVirulence Factors and Genotypes

(2015) Honghu Sun et al.   Foodborne Pathogens and Disease

Cas9 function and host genome sampling in Type II-A CRISPR–Cas adaptation

(2015) Yunzhou Wei et al.   GENES & DEVELOPMENT

CRISPR adaptation biases explain preference for acquisition of foreign DNA

(2015) Asaf Levy et al.   NATURE

Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition

(2015) Tao Liu et al.   NUCLEIC ACIDS RESEARCH

Detection and Analysis of CRISPRs of Shigella

(2014) Xiangjiao Guo et al.   CURRENT MICROBIOLOGY

Evolutionary Dynamics of the Prokaryotic Adaptive Immunity System CRISPR-Cas in an Explicit Ecological Context

(2013) J. Iranzo et al.   JOURNAL OF BACTERIOLOGY

The evolution of resistance against good and bad infections

(2013) S. Gandon et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Massive Activation of Archaeal Defense Genes during Viral Infection

(2013) T. E. F. Quax et al.   JOURNAL OF VIROLOGY

Comparative genomics of defense systems in archaea and bacteria

(2013) Kira S. Makarova et al.   NUCLEIC ACIDS RESEARCH

To be or not to be: regulation of restriction–modification systems and other toxin–antitoxin systems

(2013) Iwona Mruk et al.   NUCLEIC ACIDS RESEARCH

Physical model of the immune response of bacteria against bacteriophage through the adaptive CRISPR-Cas immune system

(2013) Pu Han et al.   PHYSICAL BIOLOGY

CRISPR-Cas

(2013) Eugene V. Koonin et al.   RNA Biology

Degeneration of a CRISPR/Cas system and its regulatory target during the evolution of a pathogen

(2013) Timothy R Sampson et al.   RNA Biology

Strong bias in the bacterial CRISPR elements that confer immunity to phage

(2013) David Paez-Espino et al.   Nature Communications

Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands

(2013) Reuben B. Vercoe et al.   PLoS Genetics

Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids

(2013) Wenyan Jiang et al.   PLoS Genetics

The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity

(2013) Bruce R. Levin et al.   PLoS Genetics

Alternative Roles for CRISPR/Cas Systems in Bacterial Pathogenesis

(2013) Timothy R. Sampson et al.   PLoS Pathogens

Evolution of animal Piwi-interacting RNAs and prokaryotic CRISPRs

(2012) M. S. Kumar et al.   Briefings in Functional Genomics

Phage mutations in response to CRISPR diversification in a bacterial population

(2012) Christine L. Sun et al.   ENVIRONMENTAL MICROBIOLOGY

A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome

(2012) R. Louwen et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

MULTISCALE MODEL OF CRISPR-INDUCED COEVOLUTIONARY DYNAMICS: DIVERSIFICATION AT THE INTERFACE OF LAMARCK AND DARWIN

(2012) Lauren M. Childs et al.   EVOLUTION

Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli

(2012) Ido Yosef et al.   NUCLEIC ACIDS RESEARCH

Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus

(2012) Jacque C. Young et al.   PLoS One

Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems

(2012) Corinna Richter et al.   Viruses-Basel

Viral Diversity Threshold for Adaptive Immunity in Prokaryotes

(2012) A. D. Weinberger et al.   mBio

Persisting Viral Sequences Shape Microbial CRISPR-based Immunity

(2012) Ariel D. Weinberger et al.   PLoS Computational Biology

Ultrafast Evolution and Loss of CRISPRs Following a Host Shift in a Novel Wildlife Pathogen, Mycoplasma gallisepticum

(2012) Nigel F. Delaney et al.   PLoS Genetics

CRISPR loci reveal networks of gene exchange in archaea

(2011) Avital Brodt et al.   Biology Direct

Evolution and classification of the CRISPR–Cas systems

(2011) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

The phage-host arms race: Shaping the evolution of microbes

(2010) Adi Stern et al.   BIOESSAYS

Envelope stress is a trigger of CRISPR RNA-mediated DNA silencing in Escherichia coli

(2010) Ritsdeliz Perez-Rodriguez et al.   MOLECULAR MICROBIOLOGY

Transcription, processing and function of CRISPR cassettes in Escherichia coli

(2010) Ksenia Pougach et al.   MOLECULAR MICROBIOLOGY

Identification and characterization ofE. coliCRISPR-caspromoters and their silencing by H-NS

(2010) Ümit Pul et al.   MOLECULAR MICROBIOLOGY

H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO

(2010) Edze R. Westra et al.   MOLECULAR MICROBIOLOGY

Self versus non-self discrimination during CRISPR RNA-directed immunity

(2010) Luciano A. Marraffini et al.   NATURE

CRISPR-mediated phage resistance and the ghost of coevolution past

(2010) P. F. Vale et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Self-targeting by CRISPR: gene regulation or autoimmunity?

(2010) Adi Stern et al.   TRENDS IN GENETICS

Multidrug-Resistant Enterococci Lack CRISPR-cas

(2010) K. L. Palmer et al.   mBio

Nasty Viruses, Costly Plasmids, Population Dynamics, and the Conditions for Establishing and Maintaining CRISPR-Mediated Adaptive Immunity in Bacteria

(2010) Bruce R. Levin   PLoS Genetics

Transcription Profile of Thermus thermophilus CRISPR Systems after Phage Infection

(2009) Yoshihiro Agari et al.   JOURNAL OF MOLECULAR BIOLOGY

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

(2009)   MICROBIOLOGY-SGM

Virus Population Dynamics and Acquired Virus Resistance in Natural Microbial Communities

(2008) A. F. Andersson et al.   SCIENCE

CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea

(2007) Rotem Sorek et al.   NATURE REVIEWS MICROBIOLOGY