Article
Multidisciplinary Sciences
Carrie Cuttler, Emily M. LaFrance, Amanda Stueber
Summary: Statewide legislation has increased access to high-potency cannabis, but federal restrictions limit access to research on low-potency whole-plant cannabis. This study examined the acute cognitive effects of high-potency cannabis, finding that high-potency flower with CBD impaired free recall, flower without CBD and concentrates affected source memory, and all three products increased susceptibility to false memories.
SCIENTIFIC REPORTS
(2021)
Review
Pharmacology & Pharmacy
Arash Salehi, Keely Puchalski, Yalda Shokoohinia, Behzad Zolfaghari, Sedigheh Asgary
Summary: Hemp and marijuana differ in terms of chemical and genetic composition, production practices, product uses, and regulatory status. Hemp seed and hemp seed oil have nutritional value, and the non-intoxicating phytocannabinoid CBD has high medicinal potential. It is now easier to differentiate between hemp and marijuana in the laboratory, and regulations and testing guidelines for cannabis are still evolving.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Albert Garcia-Romeu, Joshua Elmore, Rhiannon E. Mayhugh, Nicolas J. Schlienz, Erin L. Martin, Justin C. Strickland, Marcel Bonn-Miller, Heather Jackson, Ryan Vandrey
Summary: Medicinal cannabis users perceive benefits from cannabis use for various conditions where traditional treatments are ineffective or unacceptable. However, concerns about cannabis side effects, legality, lack of information, and cost exist. More research and education on the safety and efficacy of medicinal cannabis/cannabinoid use are warranted.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Food Science & Technology
Bettina Wagner, Pietro Gerletti, Peter Furst, Oliver Keuth, Thorsten Bernsmann, Annett Martin, Bernd Schafer, Jorge Numata, Marc C. Lorenzen, Robert Pieper
Summary: The transfer of cannabinoids from industrial hemp to milk was investigated in a feeding experiment with dairy cows. It was found that Δ(9)-THC had a transfer rate of 0.20%, exceeding the acute reference dose for humans in some scenarios of milk and dairy product consumption.
Article
Oncology
Matthew M. Cousins, Mary L. Jannausch, Lara N. Coughlin, Reshma Jagsi, Mark A. Ilgen
Summary: The study found that patients with cancer were less likely to report cannabis use, but there were different cannabis perceptions and use patterns among patients of different ages.
Article
Public, Environmental & Occupational Health
Kuo-Yu Chao, Shu-Hsiang Liu, Chih-Chiang Chou, Ching- Chen, Wei Cheng
Summary: This study surveyed Taiwanese individuals to understand their knowledge and attitudes towards the legalization of marijuana. The results showed that respondents considered the impact on public health to be a significant concern and viewed legalization as an important issue.
Review
Psychiatry
Janni Leung, Daniel Stjepanovic, Danielle Dawson, Wayne D. Hall
Summary: Research shows that some experimental studies suggest individuals can titrate their THC doses when using higher potency cannabis for recreational purposes, but there is limited evidence on whether regular cannabis users actually do so. Further experimental and epidemiological research is needed to inform regulatory policies aiming to reduce harms from the use of high THC cannabis products.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Emergency Medicine
Anita Anne Thomas, Tavis Dickerson-Young, Suzan Mazor
Summary: After the legalization of recreational marijuana in Washington State, the incidence of unintentional marijuana exposure in children increased at a tertiary care children's hospital. The majority of cases were in children aged 17 months to 7 years, with a high percentage undergoing laboratory tests, head CT scans, and social work evaluations.
PEDIATRIC EMERGENCY CARE
(2021)
Article
Anesthesiology
Calvin Diep, Chenchen Tian, Kathak Vachhani, Christine Won, Duminda N. Wijeysundera, Hance Clarke, Mandeep Singh, Karim S. Ladha
Summary: This study analyzed data from the National Health and Nutrition Examination Survey from 2005 to 2018 to investigate the relationship between cannabis use and sleep duration. The findings showed that recent cannabis use was associated with extreme sleep duration, indicating a dose-response relationship. The study emphasizes the need for further understanding of the sleep health of regular cannabis users.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2022)
Review
Ergonomics
M. B. Robertson, A. Li, Y. Yuan, A. Jiang, H. Gjerde, J. A. Staples, J. R. Brubacher
Summary: Cannabis is the second most commonly used impairing substance by drivers, and there is concern about the increase of cannabis-impaired driving as more countries legalize cannabis. However, the correlation between oral fluid THC and blood THC at the individual level is poor. Oral fluid THC testing as a biomarker for illegal THC concentrations in randomly selected drivers may result in a large number of false positive tests.
ACCIDENT ANALYSIS AND PREVENTION
(2022)
Article
Toxicology
Kelly Fong, Andy Hsueh, Kayla Kendric, Karissa Kunihira, Nadia Siddiqi, Tammy H. Phan, Ellen Reibling, Brian J. Wolk
Summary: The study explores a cluster of cases of inadvertent marijuana exposure in adults and highlights the effects on physical and psychological well-being. While most subjects tested positive for THC, none required critical care or died, but did experience symptoms and negative impacts on work. Legal constraints hinder broader research on inadvertent marijuana exposure.
CLINICAL TOXICOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Juhan Lee, Maria A. Parker
Summary: Among the young adults aged 18-25 years in the sample of 7,860 individuals, 23.8% reported vaping in the past year, and 9.7% reported cannabis driving under the influence in the past year. Past-year vaping was found to be positively associated with past-year cannabis use. Among those who used cannabis in the past year, past-year vaping was positively associated with cannabis driving under the influence.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Article
Neurosciences
Grace Blest-Hopley, Marco Colizzi, Diana Prata, Vincent Giampietro, Michael Brammer, Philip McGuire, Sagnik Bhattacharyya
Summary: High doses of THC have anxiogenic effects and their impact on brain function during fear processing can be modulated by genetic (AKT1 rs1130233) and epigenetic factors. Genetic variations at AKT1 rs1130233 and epigenetic methylation at specific CpG sites are associated with the effects of THC on brain activation during fear processing.
Article
Obstetrics & Gynecology
Jason C. Hedges, Carol B. Hanna, Lyndsey E. Shorey-Kendrick, Emily R. Boniface, Jasper C. Bash, Travis L. Rice-Stitt, Fernanda C. Burch, Rahul D'Mello, Terry K. Morgan, Ana Cristina Lima, Juanito Jose D. Terrobias, Jason A. Graham, Emily C. Mishler, Jared V. Jensen, Olivia L. Hagen, J. Wes Urian, Eliot R. Spindel, Charles A. Easley, Susan K. Murphy, Jamie O. Lo
Summary: This study used rhesus macaques as the animal model to investigate the effects of THC on male reproductive health and whether discontinuation of THC use can mitigate these effects. The results showed that chronic THC use caused testicular atrophy, decreased sex hormone levels, and changes in semen parameters, while these effects were partially restored after discontinuation of THC use.
FERTILITY AND STERILITY
(2023)
Review
Biochemistry & Molecular Biology
Andrew J. Kesner, David M. Lovinger
Summary: Cannabis sativa is the most widely used illicit drug in the world, with its main psychoactive component being THC. Despite its medical therapeutic qualities, frequent cannabis or THC users may develop cannabis use disorder, exhibiting classical addiction symptoms. Effective treatments for cannabis use disorder and withdrawal symptoms are currently lacking, highlighting the importance of research on the neurobiological mechanisms underlying these syndromes.
JOURNAL OF NEUROCHEMISTRY
(2021)
Article
Veterinary Sciences
Pamela Caye, Josaine Cristina da Silva Rappeti, Soliane Carra Perera, Hecson Jesser Segat, Patricia Silva Vives, Fabricio de Vargas Arigony Braga, Marlete Brum Cleff, Ana Raquel Mano Meinerz, Guilherme Albuquerque de Oliveira Cavalcanti, Vanessa Milech, Bernardo Nascimento Antunes, Daniel Curvello de Mendonca Muller, Mauricio Veloso Brun
Summary: This retrospective study evaluated the epidemiological, clinical, and surgical aspects of dogs infected with D. renale undergoing therapeutic nephrectomy. The study found that surgical removal of the affected kidney effectively controlled the parasitic infection and resulted in a relatively long postoperative survival time.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Review
Veterinary Sciences
Karine Cristine Almeida, Fernanda Pinto-Ferreira, Italmar Teodorico Navarro, Kamila Libano Souza, Leticia Santos Balbino, Juliana Correa Bernardes, Danielle Louisy Bahia dos Santos, Margarete Kimie Falbo
Summary: This study aimed to investigate the occurrence of zoonotic enteroparasites in dog feces from public places in Guarapuava, Brazil, and assess the knowledge of dog owners about zoonoses and public health risks. The results showed a high infection rate of zoonotic parasites in dog feces collected from public shelters, squares, parks, and roads. The survey also revealed that some dog owners did not collect their animals' feces, did not administer deworming treatments to their dogs, and were unaware of the diseases transmitted by feces.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Review
Veterinary Sciences
Deeksha Bharti, Y. Ajith, Khan Sharun, S. Amitha Banu, Akshay Kumar, Abhishek Bhardwaj, Shiv Kumar Sidar
Summary: Platelet-derived products have significant potential in regenerative medicine, particularly in tissue regeneration and complementary therapy. They offer a cost-effective and easily accessible therapeutic option for chronic inflammatory disorders, ophthalmic conditions, wound healing, and mandibular injuries in canine patients. Further research and exploration are necessary to fully understand the preparation and applicability of platelet products in canine medicine.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Article
Veterinary Sciences
Doroteja Huber, Kresimir Severin, Dunja Vlahovic, Stefani Krizanac, Sanja Mofardin, Ivana Mihokovic Buhin, Lidija Medven Zagradisnik, Ivan-Conrado Sostaric-Zuckermann, Andrea Gudan Kurilj, Branka Artukovic, Marko Hohsteter
Summary: This is a retrospective study on tumor prevalence in cats in Croatia, providing abundant histopathology findings and epidemiological data. It offers valuable insights into the most common tumors in cats from south-eastern Europe, contributing to the field of clinical veterinary oncology.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)