Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features

From intracellular signaling to population oscillations: bridging size- and time-scales in collective behavior

(2015) A. E. Sgro et al.   Molecular Systems Biology

Computational analysis of signaling patterns in single cells

(2015) Denise M. Davis et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Recent Developments in Microfluidics for Cell Studies

(2014) Bin Xiong et al.   ADVANCED MATERIALS

Reciprocal Encoding of Signal Intensity and Duration in a Glucose-Sensing Circuit

(2014) Yan Fu et al.   CELL

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

(2014) Sean C. Bendall et al.   CELL

Cellular noise and information transmission

(2014) Andre Levchenko et al.   CURRENT OPINION IN BIOTECHNOLOGY

Fluorescence fluctuation microscopy: a diversified arsenal of methods to investigate molecular dynamics inside cells

(2014) Thomas Weidemann et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Inputs drive cell phenotype variability

(2014) J. Park et al.   GENOME RESEARCH

Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals

(2014) Evan J Olson et al.   NATURE METHODS

Information transfer by leaky, heterogeneous, protein kinase signaling systems

(2014) M. Voliotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Switching of the Relative Dominance Between Feedback Mechanisms in Lipopolysaccharide-Induced NF- B Signaling

(2014) M.-H. Sung et al.   Science Signaling

Dynamic signal encoding—From cells to organisms

(2014) Katharina F. Sonnen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

The Dynamics of Signaling as a Pharmacological Target

(2013) Marcelo Behar et al.   CELL

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

(2013) Siim Pauklin et al.   CELL

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Design Principles of Regulatory Networks: Searching for the Molecular Algorithms of the Cell

(2013) Wendell A. Lim et al.   MOLECULAR CELL

Barriers to transmission of transcriptional noise in a c-fos c-jun pathway

(2013) K. Shah et al.   Molecular Systems Biology

Positional information, in bits

(2013) J. O. Dubuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Roles of Pulsing in Genetic Circuits

(2013) J. H. Levine et al.   SCIENCE

Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

(2012) Marc R Birtwistle et al.   BMC Systems Biology

Network Crosstalk Dynamically Changes during Neutrophil Polarization

(2012) Chin-Jen Ku et al.   CELL

Investigating transcriptional states at single-cell-resolution

(2012) Julia Tischler et al.   CURRENT OPINION IN BIOTECHNOLOGY

Decoding the Insulin Signal

(2012) Jeremy E. Purvis et al.   MOLECULAR CELL

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

Identifying sources of variation and the flow of information in biochemical networks

(2012) C. G. Bowsher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integration of cellular signals in chattering environments

(2012) P. Rué et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

Interplay between gene expression noise and regulatory network architecture

(2012) Guilhem Chalancon et al.   TRENDS IN GENETICS

Information theory based approaches to cellular signaling

(2011) Christian Waltermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory network

(2011) Gregory M Miller et al.   BMC Systems Biology

Impulse Control: Temporal Dynamics in Gene Transcription

(2011) Nir Yosef et al.   CELL

General formulation of HDMR component functions with independent and correlated variables

(2011) Genyuan Li et al.   JOURNAL OF MATHEMATICAL CHEMISTRY

Light-based feedback for controlling intracellular signaling dynamics

(2011) Jared E Toettcher et al.   NATURE METHODS

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Feedback regulation of EGFR signalling: decision making by early and delayed loops

(2011) Roi Avraham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signal-dependent dynamics of transcription factor translocation controls gene expression

(2011) Nan Hao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics

(2010) Takashi Nakakuki et al.   CELL

Understanding the temporal codes of intra-cellular signals

(2010) Marcelo Behar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Physiological levels of TNF  stimulation induce stochastic dynamics of NF- B responses in single living cells

(2010) D. A. Turner et al.   JOURNAL OF CELL SCIENCE

Measurement of single-cell dynamics

(2010) David G. Spiller et al.   NATURE

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

Cell signaling: What is the signal and what information does it carry?

(2009) Roger Brent   FEBS LETTERS

Dynamics and Variability of ERK2 Response to EGF in Individual Living Cells

(2009) Cellina Cohen-Saidon et al.   MOLECULAR CELL

Information processing and signal integration in bacterial quorum sensing

(2009) Pankaj Mehta et al.   Molecular Systems Biology

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

(2009) Vladimir Litvak et al.   NATURE IMMUNOLOGY

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Information flow and optimization in transcriptional regulation

(2008) G. Tkacik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA