Signal Transduction by a Fungal NOD-Like Receptor Based on Propagation of a Prion Amyloid Fold

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

(2014) Xin Cai et al.   CELL

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

Diversity and Variability of NOD-Like Receptors in Fungi

(2014) Witold Dyrka et al.   Genome Biology and Evolution

Natural Variation of Heterokaryon Incompatibility Gene het-c in Podospora anserina Reveals Diversifying Selection

(2014) Eric Bastiaans et al.   MOLECULAR BIOLOGY AND EVOLUTION

Staying Alive: Cell Death in Antiviral Immunity

(2014) Jason W. Upton et al.   MOLECULAR CELL

Fungal prion HET-s as a model for structural complexity and self-propagation in prions

(2014) W. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of Specific Residues of the β-Solenoid Fold to HET-s Prion Function, Amyloid Structure and Stability

(2014) Asen Daskalov et al.   PLoS Pathogens

ATR-FTIR: A “rejuvenated” tool to investigate amyloid proteins

(2013) Rabia Sarroukh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

Parallel β-Sheet Fibril and Antiparallel β-Sheet Oligomer: New Insights into Amyloid Formation of Hen Egg White Lysozyme under Heat and Acidic Condition from FTIR Spectroscopy

(2013) Ye Zou et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Apoptosome Structure, Assembly, and Procaspase Activation

(2013) Shujun Yuan et al.   STRUCTURE

The Transcriptional Response to Nonself in the Fungus Podospora anserina

(2013) Frédérique Bidard et al.   G3-Genes Genomes Genetics

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

A new eye on NLR proteins: focused on clarity or diffused by complexity?

(2012) Vera Bonardi et al.   CURRENT OPINION IN IMMUNOLOGY

Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin

(2012) Els F. Halff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic Clustering and Homology between HET-S and the NWD2 STAND Protein in Various Fungal Genomes

(2012) Asen Daskalov et al.   PLoS One

High natural prevalence of a fungal prion

(2012) A. J. M. Debets et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mechanism of Toxicity in HET-S/HET-s Prion Incompatibility

(2012) Carolin Seuring et al.   PLOS BIOLOGY

The [Het-s] Prion, an Amyloid Fold as a Cell Death Activation Trigger

(2012) Sven J. Saupe et al.   PLoS Pathogens

Temperature Dependence of the Aggregation Kinetics of Sup35 and Ure2p Yeast Prions

(2011) Raimon Sabaté et al.   BIOMACROMOLECULES

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

The machinery of Nod-like receptors: refining the paths to immunity and cell death

(2011) Maya Saleh   IMMUNOLOGICAL REVIEWS

Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation

(2011) Birte Zurek et al.   Innate Immunity

Localization of HET-S to the Cell Periphery, Not to [Het-s] Aggregates, Is Associated with [Het-s]-HET-S Toxicity

(2011) V. Mathur et al.   MOLECULAR AND CELLULAR BIOLOGY

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

NLR functions in plant and animal immune systems: so far and yet so close

(2011) Takaki Maekawa et al.   NATURE IMMUNOLOGY

Interactions between non-identical prion proteins

(2011) Aaron C. Gonzalez Nelson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission

(2011) Ines Moreno-Gonzalez et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The [Het-s] prion of Podospora anserina and its role in heterokaryon incompatibility

(2011) Sven J. Saupe   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

WD-repeat instability and diversification of the Podospora anserina hnwd non-self recognition gene family

(2010) Damien Chevanne et al.   BMC EVOLUTIONARY BIOLOGY

What is new with Nods?

(2010) Joao G Magalhaes et al.   CURRENT OPINION IN IMMUNOLOGY

Structural Determination and Tryptophan Fluorescence of Heterokaryon Incompatibility C2 Protein (HET-C2), a Fungal Glycolipid Transfer Protein (GLTP), Provide Novel Insights into Glycolipid Specificity and Membrane Interaction by the GLTP Fold

(2010) Roopa Kenoth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Similarity between the Prion Domain of HET-s and a Homologue Can Explain Amyloid Cross-Seeding in Spite of Limited Sequence Identity

(2010) Christian Wasmer et al.   JOURNAL OF MOLECULAR BIOLOGY

Atomic-Resolution Three-Dimensional Structure of HET-s(218−289) Amyloid Fibrils by Solid-State NMR Spectroscopy

(2010) Hélène Van Melckebeke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Mechanism of Prion Inhibition by HET-S

(2010) Jason Greenwald et al.   MOLECULAR CELL

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Solid-State NMR Spectroscopy Reveals thatE. coliInclusion Bodies of HET-s(218-289) are Amyloids

(2009) Christian Wasmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fungal incompatibility: Evolutionary origin in pathogen defense?

(2009) Mathieu Paoletti et al.   BIOESSAYS

Identification of the het-r vegetative incompatibility gene of Podospora anserina as a member of the fast evolving HNWD gene family

(2009) Damien Chevanne et al.   CURRENT GENETICS

Characterization of different water pools in solid-state NMR protein samples

(2009) Anja Böckmann et al.   JOURNAL OF BIOMOLECULAR NMR

Wheel of Life, Wheel of Death: A Mechanistic Insight into Signaling by STAND Proteins

(2009) Olivier Danot et al.   STRUCTURE

Infectious and Noninfectious Amyloids of the HET‐s(218–289) Prion Have Different NMR Spectra

(2008) Christian Wasmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondrial pAL2-1 plasmid homologs are senescence factors inPodospora anserina independent of intrinsic senescence

(2008) Anne D. van Diepeningen et al.   Biotechnology Journal

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

(2008) C. Wasmer et al.   SCIENCE

Prion agent diversity and species barrier

(2008) Vincent Béringue et al.   VETERINARY RESEARCH