Purinergic Signaling in Early Inflammatory Events of the Foreign Body Response: Modulating Extracellular ATP as an Enabling Technology for Engineered Implants and Tissues

The effect of encapsulation of cardiac stem cells within matrix-enriched hydrogel capsules on cell survival, post-ischemic cell retention and cardiac function

(2013) Audrey E. Mayfield et al.   BIOMATERIALS

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

(2013) Sylvia S Amaral et al.   Cell Communication and Signaling

Improving survival and efficacy of pluripotent stem cell-derived cardiac grafts

(2013) Creighton W. Don et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In Vivo Imaging Demonstrates ATP Release from Murine Keratinocytes and Its Involvement in Cutaneous Inflammation after Tape Stripping

(2013) Toshiya Takahashi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integration of Scaffolds into Full-Thickness Skin Wounds: The Connexin Response

(2013) Daniel J. Gilmartin et al.   Advanced Healthcare Materials

Regulation of Neutrophil Function by Adenosine

(2012) Kathryn E. Barletta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Monocyte–endothelial adhesion is modulated by Cx43-stimulated ATP release from monocytes

(2012) Dongdong Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ABC transporters and their role in nucleoside and nucleotide drug resistance

(2012) Yu Fukuda et al.   BIOCHEMICAL PHARMACOLOGY

Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future

(2012) Geoffrey Burnstock   BIOESSAYS

Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine

(2012) Bryan N. Brown et al.   BIOMATERIALS

Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts

(2012) James D. Bryers et al.   BIOTECHNOLOGY AND BIOENGINEERING

Embryonic wound healing: A primer for engineering novel therapies for tissue repair

(2012) Katherine E. Degen et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Purines, Purinergic Receptors, and Cancer

(2012) F. Di Virgilio   CANCER RESEARCH

Mechanisms of ATP release and signalling in the blood vessel wall

(2012) A. W. Lohman et al.   CARDIOVASCULAR RESEARCH

Agarose Gel as Biomaterial or Scaffold for Implantation Surgery: Characterization, Histological and Histomorphometric Study on Soft Tissue Response

(2012) Elena Varoni et al.   CONNECTIVE TISSUE RESEARCH

Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala

(2012) Jimmy Stehberg et al.   FASEB JOURNAL

Targeting the intragraft microenvironment and the development of chronic allograft rejection

(2012) Olivier Dormond et al.   HUMAN IMMUNOLOGY

The challenges and promises of new therapies for cystic fibrosis: Figure 1.

(2012) Gerald B. Pier   JOURNAL OF EXPERIMENTAL MEDICINE

Cx43 Associates with Nav1.5 in the Cardiomyocyte Perinexus

(2012) J. Matthew Rhett et al.   JOURNAL OF MEMBRANE BIOLOGY

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular and functional properties of P2X receptors—recent progress and persisting challenges

(2012) Karina Kaczmarek-Hájek et al.   Purinergic Signalling

Vesicular and conductive mechanisms of nucleotide release

(2012) Eduardo R. Lazarowski   Purinergic Signalling

Thrombin-induced ATP release from human umbilical vein endothelial cells

(2011) Stefanie Gödecke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pathogenesis of Antineutrophil Cytoplasmic Autoantibody–Associated Small-Vessel Vasculitis

(2011) J. Charles Jennette et al.   Annual Review of Pathology-Mechanisms of Disease

Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials

(2011) Sandra Franz et al.   BIOMATERIALS

Active leukocyte detachment and apoptosis/necrosis on PEG hydrogels and the implication in the host inflammatory response

(2011) Heather Waldeck et al.   BIOMATERIALS

Purinergic signaling in embryonic and stem cell development

(2011) Geoffrey Burnstock et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Peptide Mimetic of the Connexin43 Carboxyl Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury

(2011) Michael P. O'Quinn et al.   CIRCULATION RESEARCH

Purinergic Signaling in Healthy and Diseased Skin

(2011) Geoffrey Burnstock et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

(2011) Juan A. Orellana et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid  -Induced Death in Neurons Involves Glial and Neuronal Hemichannels

(2011) J. A. Orellana et al.   JOURNAL OF NEUROSCIENCE

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

(2011) J. Matthew Rhett et al.   MOLECULAR BIOLOGY OF THE CELL

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Biomaterials/Tissue Interactions: Possible Solutions to Overcome Foreign Body Response

(2010) Jacqueline M. Morais et al.   AAPS Journal

Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]

(2010) D. Song et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Cystic fibrosis transmembrane conductance regulator (CFTR) expression in human platelets: impact on mediators and mechanisms of the inflammatory response

(2010) Domenico Mattoscio et al.   FASEB JOURNAL

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity

(2010) Raf Ponsaerts et al.   FASEB JOURNAL

Involvement of the cystic fibrosis transmembrane conductance regulator in the acidosis-induced efflux of ATP from rat skeletal muscle

(2010) Jie Tu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Role of ATP in the ROS-mediated laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats

(2009) Tung-Lung Tsai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39

(2009) Matthew C. Hyman et al.   JOURNAL OF CLINICAL INVESTIGATION

Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium

(2009) Joseph A. Palatinus et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Connexin43 Carboxyl-Terminal Peptide ACT1 Modulates the Biological Response to Silicone Implants

(2009) Brent L. Soder et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding

(2009) Gautam S Ghatnekar et al.   Regenerative Medicine

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model

(2008) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Magnetic Resonance Imaging Overestimates Ferumoxide-Labeled Stem Cell Survival After Transplantation in the Heart

(2008) John Terrovitis et al.   CIRCULATION

ATP release by cardiac myocytes in a simulated ischaemia model

(2008) Thomas C. Clarke et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs

(2008) Jörg Reutershan et al.   FASEB JOURNAL

A Central Role of Connexin 43 in Hypoxic Preconditioning

(2008) J. H.-C. Lin et al.   JOURNAL OF NEUROSCIENCE

Identification of a vesicular nucleotide transporter

(2008) K. Sawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear

(2008) F. Anselmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of shear-induced ATP release from red blood cells

(2008) J. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the Inflammatory Response for Enhanced Bone Tissue Regeneration

(2008) Paschalia M. Mountziaris et al.   TISSUE ENGINEERING PART B-REVIEWS

Novel therapies for scar reduction and regenerative healing of skin wounds

(2008) J. Matthew Rhett et al.   TRENDS IN BIOTECHNOLOGY

Purinergic signalling in the nervous system: an overview

(2008) Maria P. Abbracchio et al.   TRENDS IN NEUROSCIENCES