Article
Biotechnology & Applied Microbiology
Anne Metje van Genderen, Katja Jansen, Marleen Kristen, Joost van Duijn, Yang Li, Carl C. L. Schuurmans, Jos Malda, Tina Vermonden, Jitske Jansen, Rosalinde Masereeuw, Miguel Castilho
Summary: This study successfully fabricated small-diameter, highly organized tubular fibrous scaffolds using melt-electrowriting (MEW) technology, and seeded them with human umbilical vein endothelial cells and human conditionally immortalized proximal tubular epithelial cells, demonstrating improved cell functionality and potential for implantation as kidney tubules.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Shuai Chen, Carmen J. Gil, Liqun Ning, Linqi Jin, Lilanni Perez, Gabriella Kabboul, Martin L. Tomov, Vahid Serpooshan
Summary: This article discusses the significance of Adhesive Tissue Engineering Scaffolds (ATESs), reviewing their key characteristics and requirements, exploring mechanisms of action for securing the scaffold onto tissue, and presenting strategies for assessing adhesive properties. Current applications and future prospects of advanced ATES systems in regenerative medicine therapies are highlighted, along with key challenges in various fields of tissue engineering.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Saeed Hesaraki, Mohammad Nouri-Felekori, Nader Nezafati, Shokoufeh Borhan
Summary: In this study, composite scaffolds containing tragacanth gum and bioactive glass nanoparticles were successfully fabricated, showing promising characteristics for bone tissue engineering applications. Morphological observations and characterization analysis confirmed the impact of BGNPs on scaffold structure and degradation rate.
MATERIALS TODAY COMMUNICATIONS
(2021)
Review
Engineering, Biomedical
Xiaolian Niu, Ning Li, Zhipo Du, Xiaoming Li
Summary: This review discusses the challenges and current efforts in the field of tissue engineering for osteochondral defect repair, with a focus on establishing satisfactory integrated gradient tissue-engineered osteochondral scaffold (IGTEOS) and achieving simultaneous regeneration of both cartilage and subchondral bone.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Paula F. Gouveia, Joana Mesquita-Guimaraes, Maria E. Galarraga-Vinueza, Julio C. M. Souza, Filipe S. Silva, Marcio C. Fredel, Aldo R. Boccaccini, Rainer Detsch, Bruno Henriques
Summary: This study aimed to evaluate the mechanical properties and biological response of novel zirconia reinforced bioactive glass scaffolds. The results showed that the ZRBG scaffolds exhibited higher bioactivity and cell viability compared to zirconia scaffolds.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Review
Biotechnology & Applied Microbiology
Aaqil Rifai, D. Kavindi Weerasinghe, Gebreselassie Addisu Tilaye, David Nisbet, Jason M. M. Hodge, Julie A. A. Pasco, Lana J. J. Williams, Rasika M. M. Samarasinghe, Richard J. J. Williams
Summary: Damage to bone can lead to pain and restricted movement. Tissue engineering is being explored as a clinical solution for bone defects. However, there are still significant challenges in creating complex bone substitutes that can mimic the natural growth and differentiation of bone cells. This review provides an overview of bone structure, the role of bone cells, and the development of tissue-engineered bone designs.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Polymer Science
Liang Lu, Xifu Shang, Bin Liu, Weijian Chen, Yu Zhang, Shuyun Liu, Xiang Sui, Aiyuan Wang, Quanyi Guo
Summary: This paper explores the application value of tissue engineering in vitro for the construction of artificial cartilage. By seeding healthy porcine chondrocytes on articular cartilage extracellular matrix (ACECM) scaffolds, it was found that the cells performed well in terms of adhesion and growth on the scaffolds, and they secreted collagen type II. Moreover, the porcine ACECM scaffolds showed good biocompatibility and could be used for xenotransplantation without significant immune inflammatory response. Therefore, ACECM-oriented scaffold is an ideal natural biomaterial for cartilage tissue engineering.
Review
Biochemistry & Molecular Biology
Saeed Farzamfar, Megan Richer, Mahya Rahmani, Mohammad Naji, Mehdi Aleahmad, Stephane Chabaud, Stephane Bolduc
Summary: Urethral reconstruction strategies are limited due to lack of suitable tissues that can withstand urine exposure. However, tissue engineering using biological macromolecule-based scaffolds offers potential solutions to prevent urine leakage. This review discusses recent advances, applications, and challenges in urethral reconstruction using biological macromolecule-based scaffolds.
Article
Polymer Science
Phillip R. Schmitt, Kiera D. Dwyer, Alicia J. Minor, Kareen L. K. Coulombe
Summary: Myocardial infarction is a leading cause of death globally, and cardiac tissue engineering using hiPSC-CMs aims to re-engineer the infarcted myocardium. The current challenges in this technology include maintaining tissue integrity and inducing cell function, while biodegradable PCL scaffolds offer a solution.
Review
Engineering, Environmental
Robin Augustine, Mert Gezek, Nazli Seray Bostanci, Angelina Nguyen, Gulden Camci-Unal
Summary: The lack of oxygen supply in engineered constructs poses a major challenge in tissue engineering and regenerative medicine. Providing and maintaining adequate oxygen levels in large tissue-engineered constructs as well as during transportation and storage is crucial. Recent approaches involve incorporating oxygen-generating materials such as peroxides and fluorinated substances into scaffolds. This review paper highlights the importance of oxygen-generating materials in various tissue engineering approaches and discusses challenges, solutions, and future strategies in designing clinically relevant multifunctional biomaterials.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Dalila Di Francesco, Alexa Pigliafreddo, Simona Casarella, Luca Di Nunno, Diego Mantovani, Francesca Boccafoschi
Summary: The clinical demand for tissue-engineered vascular grafts is increasing, and there are many challenges to obtain functional small-diameter grafts. Advances in cell culture, biomaterials, manufacturing techniques, and tissue engineering methods have led to promising solutions for vascular graft production. The use of natural materials as scaffolds for vascular tissue engineering has gained attention and new strategies have been developed to overcome the drawbacks.
Article
Chemistry, Physical
Lei Zhan, Lingtian Wang, Jixia Deng, Yi Zheng, Qinfei Ke, Xinrui Yang, Xing Zhang, Weitao Jia, Chen Huang
Summary: Nanogrooved microfiber scaffold shows improved cell adhesion and infiltration, making it important for tissue engineering and wound healing.
Article
Chemistry, Multidisciplinary
Samila Leon-Chaviano, Mariia Kiseleva, Philippe Legros, Simon Collin, Theophraste Lescot, Celine Henoumont, Yves Gossuin, Sophie Laurent, Dominique Mayrand, Julie Fradette, Andre Begin-Drolet, Jean Ruel, Marc-Andre Fortin
Summary: In this study, a magnetic ink based on ultra-small iron oxide nanoparticles is developed and integrated into biocompatible alginate hydrogel used in cell scaffolding applications. It is found that this magnetic hydrogel can produce positive contrast in magnetic resonance imaging to clearly visualize the contours of tissue grafts.
Article
Polymer Science
Sara Biscaia, Joao C. Silva, Carla Moura, Tania Viana, Ana Tojeira, Geoffrey R. Mitchell, Paula Pascoal-Faria, Frederico Castelo Ferreira, Nuno Alves
Summary: Understanding the coupling mechanisms between mechanics and biology in biomaterials is crucial for tissue engineering. This study investigates the effects of adding graphene nanoparticles on the mechanical and biological properties of a poly(epsilon-caprolactone) scaffold. The results show that adding 0.5% graphene nanoparticles significantly improves the compressive modulus of the scaffold and supports cell adhesion, proliferation, and migration.
Article
Biotechnology & Applied Microbiology
Honghua Kang, Yi Han, Mengyi Jin, Lan Zheng, Zhen Liu, Yuhua Xue, Zuguo Liu, Cheng Li
Summary: Corneal blindness is a leading cause of vision loss globally, and corneal transplantation is the most effective method to restore vision. However, there is often a shortage of donor corneas for transplantation. This study developed a novel method using squid mantle as a biomaterial to prepare a tissue-engineered corneal substitute. The decellularized squid mantle scaffold showed high efficiency, rich essential amino acids, and maintained regular fiber alignment. The results suggested that squid mantle could be a potential tissue-engineered corneal stroma material with promising clinical applications.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ahmad M. Eweida, Raymund E. Horch, Mona K. Marei, Habashi A. Elhammady, Ashraf N. Etaby, Ayman S. Nabawi, Mahmoud F. Sakr
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2015)
Article
Medicine, Research & Experimental
Ibrahim Fathi, Habashi Elhammady, Mahmoud Sakr, Ayman Nabawi, Mona Marei
XENOTRANSPLANTATION
(2015)
Review
Biotechnology & Applied Microbiology
A. M. Eweida, M. K. Marei
BIOMED RESEARCH INTERNATIONAL
(2015)
Review
Orthopedics
A. M. Eweida, A. S. Nabawi, H. A. Elhammady, M. K. Marei, M. R. Khalil, M. S. Shawky, A. Arkudas, J. P. Beier, F. Unglaub, U. Kneser, R. E. Horch
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2012)
Article
Dentistry, Oral Surgery & Medicine
Ahmad Mahmoud Eweida, Ayman Sameh Nabawi, Mohamed Abouarab, Mohamed Kayed, Habashi Elhammady, Ashraf Etaby, Mohamed Rafik Khalil, Michael Samir Shawky, Ulrich Kneser, Raymund E. Horch, Naglaa Nagy, Mona Kamal Marei
CLINICAL ORAL INVESTIGATIONS
(2014)
Article
Dentistry, Oral Surgery & Medicine
Rania M. El Backly, Samer H. Zaky, Barbara Canciani, Manal M. Saad, Ahmed M. Eweida, Francesco Brun, Giuliana Tromba, Vladimir S. Komlev, Maddalena Mastrogiacomo, Mona K. Marei, Ranieri Cancedda
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2014)
Article
Engineering, Biomedical
S. Wang, M. M. Falk, A. Rashad, M. M. Saad, A. C. Marques, R. M. Almeida, M. K. Marei, H. Jain
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2011)
Article
Chemistry, Multidisciplinary
Mohamad Nageeb, Samir R. Nouh, Kristoffer Bergman, Naglaa B. Nagy, Dalia Khamis, Marta Kisiel, Thomas Engstrand, Jons Hilborn, Mona K. Marei
MOLECULAR CRYSTALS AND LIQUID CRYSTALS
(2012)
Article
Materials Science, Ceramics
Suman Saha, Arnab Bhattacharjee, Sk. Hasanur Rahaman, Sayantan Ray, Mona K. Marei, Himanshu Jain, Jui Chakraborty
INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE
(2020)
Article
Polymer Science
Ahmed Abd El-Fattah, Mohamad Nageeb Hassan, Ahmad Rashad, Mona Marei, Sherif Kandil
INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION
(2020)
Article
Chemistry, Physical
Noha Elshazly, Abdelaziz Khalil, Manal Saad, Marco Patruno, Jui Chakraborty, Mona Marei
Article
Dentistry, Oral Surgery & Medicine
M. S. Saad, M. Fata, A. Farouk, A. M. A. Habib, M. Gad, M. B. Tayel, M. K. Marei
JDR CLINICAL & TRANSLATIONAL RESEARCH
(2020)
Proceedings Paper
Computer Science, Information Systems
Rania M. Moussa, Magdy A. Awadalla, Mona K. Marei, Tamer M. Nassef
COMPLEX ADAPTIVE SYSTEMS, 2015
(2015)
Review
Biotechnology & Applied Microbiology
Mona K. Marei, Rania M. El Backly
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2018)