Insights into the pathogenesis of GvHD: what mice can teach us about man

Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease

(2014) Ernst Holler et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

(2014) J. M. Munneke et al.   BLOOD

CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

(2014) Kylie A. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of Mammalian Target of Rapamycin Inhibition on Lymphoid Homing and Tolerogenic Function of Nanoparticle-Labeled Dendritic Cells following Allogeneic Hematopoietic Cell Transplantation

(2014) W. Reichardt et al.   JOURNAL OF IMMUNOLOGY

Monocyte-Induced Development of Th17 Cells and the Release of S100 Proteins Are Involved in the Pathogenesis of Graft-versus-Host Disease

(2014) Katharina Reinhardt et al.   JOURNAL OF IMMUNOLOGY

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage

(2014) Lukas Schwab et al.   NATURE MEDICINE

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Inflammatory neovascularization during graft-versus-host disease is regulated by  v integrin and miR-100

(2013) F. Leonhardt et al.   BLOOD

Identification of CD3 + CD4 − CD8 − T Cells as Potential Regulatory Cells in an Experimental Murine Model of Graft-Versus-Host Skin Disease (GVHD)

(2013) Fumi Miyagawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

(2013) Tayfun Güngör et al.   LANCET

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

(2013) Sung Won Choi et al.   LANCET ONCOLOGY

Effects of Trichostatin A in a Rat Model of Acute Graft-Versus-Host Disease After Liver Transplantation

(2013) Xuefeng Xia et al.   TRANSPLANTATION

Innate Lymphoid Cells: Emerging Insights in Development, Lineage Relationships, and Function

(2012) Hergen Spits et al.   Annual Review of Immunology

Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells

(2012) A.-K. Hechinger et al.   HAEMATOLOGICA

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

(2012) Alan M. Hanash et al.   IMMUNITY

Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease

(2012) Gregory F. Sonnenberg et al.   IMMUNITY

Graft-versus-host disease reduces regulatory T-cell migration into the tumour tissue

(2012) Christoph Dürr et al.   IMMUNOLOGY

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

(2012) Robert R. Jenq et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels

(2012) F Leonhardt et al.   LEUKEMIA

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

(2012) J. A. Dudakov et al.   SCIENCE

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Excellent survival after sibling or unrelated donor stem cell transplantation for chronic granulomatous disease

(2011) Caridad A. Martinez et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

(2011) Daigo Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

(2011) Motoko Koyama et al.   NATURE MEDICINE

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic Efficacy of Cord Blood-Derived Mesenchymal Stromal Cells for the Prevention of Acute Graft-Versus-Host Disease in a Xenogenic Mouse Model

(2011) Joëlle Gregoire-Gauthier et al.   STEM CELLS AND DEVELOPMENT

Prophylaxis with Sirolimus and Tacrolimus ± Antithymocyte Globulin Reduces the Risk of Acute Graft-versus-Host Disease without an Overall Survival Benefit Following Allogeneic Stem Cell Transplantation

(2010) Lindsay L. Rosenbeck et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

(2010) K. P. A. MacDonald et al.   BLOOD

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Single Round of Antigen Receptor Signaling Programs Naive B Cells to Receive T Cell Help

(2010) Bazarragchaa Damdinsuren et al.   IMMUNITY

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

(2010) Konrad Wilhelm et al.   NATURE MEDICINE

Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation

(2010) Ted A. Gooley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of macrophage infiltration of skin lesions on survival after allogeneic stem cell transplantation: a clue to refractory graft-versus-host disease

(2009) S. Nishiwaki et al.   BLOOD

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Interleukin-17–Producing T-Helper Cells as New Potential Player Mediating Graft-Versus-Host Disease in Patients Undergoing Allogeneic Stem-Cell Transplantation

(2009) Erica Dander et al.   TRANSPLANTATION

Highly Sensitive Model for Xenogenic GVHD Using Severe Immunodeficient NOG Mice

(2009) Ryoji Ito et al.   TRANSPLANTATION

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

(2008) M. J. Carlson et al.   BLOOD

GVHD after chemotherapy conditioning in allogeneic transplanted mice

(2008) B Sadeghi et al.   BONE MARROW TRANSPLANTATION

Reduced Intensity Conditioning for Allogeneic Hematopoietic Stem-Cell Transplant Determines the Kinetics of Acute Graft-Versus-Host Disease

(2008) Brie E. Turner et al.   TRANSPLANTATION