Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis

Pleiotropic effects of factor Xa and thrombin: what to expect from novel anticoagulants

(2014) H. M. H. Spronk et al.   CARDIOVASCULAR RESEARCH

Warfarin Induces Cardiovascular Damage in Mice

(2013) Thilo Krüger et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transactivation of the PAR1-PAR2 Heterodimer by Thrombin Elicits β-Arrestin-mediated Endosomal Signaling

(2013) Huilan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-activated Receptor 1 (PAR1) and PAR4 Heterodimers Are Required for PAR1-enhanced Cleavage of PAR4 by α-Thrombin

(2013) Amal Arachiche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombin generation and atherosclerosis

(2013) Jana Kalz et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

New Fundamentals in Hemostasis

(2013) Henri H. Versteeg et al.   PHYSIOLOGICAL REVIEWS

Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner

(2013) Julian I. Borissoff et al.   PLoS One

Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization

(2013) Leon J. Schurgers et al.   TRENDS IN MOLECULAR MEDICINE

Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists

(2012) Martijn L.L. Chatrou et al.   BLOOD REVIEWS

Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa

(2012) P. E. J. VAN DER MEIJDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The impact of blood coagulability on atherosclerosis and cardiovascular disease

(2012) R. LOEFFEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype

(2012) Leon J. Schurgers et al.   PLoS One

Accelerated In Vivo Thrombin Formation Independently Predicts the Presence and Severity of CT Angiographic Coronary Atherosclerosis

(2012) Julian I. Borissoff et al.   JACC-Cardiovascular Imaging

Protease-Activated Receptor-2 Modulates Protease-Activated Receptor-1–Driven Neointimal Hyperplasia

(2011) Leila M. Sevigny et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Coronary Artery Calcification in Hemophilia A

(2011) Attie Tuinenburg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of dietary vitamin K in the management of oral vitamin K antagonists

(2011) Michael V. Holmes et al.   BLOOD REVIEWS

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

(2011) Catherine M. Shanahan et al.   CIRCULATION RESEARCH

Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

(2011) Alexander N. Kapustin et al.   CIRCULATION RESEARCH

Management of atrial fibrillation around the world: a comparison of current ACCF/AHA/HRS, CCS, and ESC guidelines

(2011) K. Wasmer et al.   EUROPACE

Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients

(2011) B. Weijs et al.   EUROPEAN HEART JOURNAL

Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment

(2011) K. A. A. Fox et al.   EUROPEAN HEART JOURNAL

Blood coagulation factor Xa as an emerging drug target

(2011) Keren Borensztajn et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Anticoagulants

(2011) M. Levi et al.   Hamostaseologie

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

Treatment with an oral direct thrombin inhibitor decreases platelet activity but increases markers of inflammation in patients with myocardial infarction

(2011) C. Christersson et al.   JOURNAL OF INTERNAL MEDICINE

Coronary artery calcification score and carotid intima-media thickness in patients with hemophilia

(2011) M. ZWIERS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban

(2011) Qianxing Zhou et al.   MEDIATORS OF INFLAMMATION

The Hemostatic System as a Modulator of Atherosclerosis

(2011) Julian Ilcheff Borissoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apixaban versus Warfarin in Patients with Atrial Fibrillation

(2011) Christopher B. Granger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

(2011) Manesh R. Patel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Atherosclerosis Exhibits an Enhanced Procoagulant State

(2010) Julian Ilcheff Borissoff et al.   CIRCULATION

Factor X/Xa Elicits Protective Signaling Responses in Endothelial Cells Directly via PAR-2 and Indirectly via Endothelial Protein C Receptor-dependent Recruitment of PAR-1

(2010) Jong-Sup Bae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leech-Derived Thrombin Inhibitors: From Structures to Mechanisms to Clinical Applications

(2010) María Ángeles Corral-Rodríguez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Clotting Problems: Diagnosis and Management of Underlying Coagulopathies

(2010) Rabih Houbballah et al.   Seminars in Vascular Surgery

Atherosclerosis proceeds independently of thrombin-induced platelet activation in ApoE−/− mice

(2009) J.R. Hamilton et al.   ATHEROSCLEROSIS

Coronary atherosclerosis and cardiovascular mortality in hemophilia

(2009) C. J. FOLEY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dabigatran versus Warfarin in Patients with Atrial Fibrillation

(2009) Stuart J. Connolly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prothrombin fragment 1+2 is associated with intima media thickness of the carotid artery in patients with myocardial infarction

(2009) Loghman Henareh et al.   THROMBOSIS RESEARCH

Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells

(2008) Alexandra E. Ewence et al.   CIRCULATION RESEARCH

Aortic Atherosclerosis, Hypercoagulability, and Stroke

(2008) Marco R. Di Tullio et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease

(2008) Keren Borensztajn et al.   TRENDS IN MOLECULAR MEDICINE