The various states of von Willebrand factor and their function in physiology and pathophysiology

An atypical manifestation of acquired von Willebrand syndrome (AVWS) associated with systemic lupus erythematosus (SLE)

(2013) Priyanka Kasatkar et al.   ANNALS OF HEMATOLOGY

Circulating but not immobilized N-deglycosylated von Willebrand factor increases platelet adhesion under flow conditions

(2013) M. A. Fallah et al.   Biomicrofluidics

Von Willlebrand Adhesion to Surfaces at High Shear Rates Is Controlled by Long-Lived Bonds

(2013) Charles E. Sing et al.   BIOPHYSICAL JOURNAL

Ultralarge von Willebrand Factor Fibers Mediate Luminal Staphylococcus aureus Adhesion to an Intact Endothelial Cell Layer Under Shear Stress

(2013) Karin I. Pappelbaum et al.   CIRCULATION

The N-terminal Flanking Region of the A1 Domain Regulates the Force-dependent Binding of von Willebrand Factor to Platelet Glycoprotein Ibα

(2013) Lining Ju et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation

(2013) Carina Hillgruber et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Clearance of von Willebrand factor

(2013) C. Casari et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A practical guide to quantify cell adhesion using single-cell force spectroscopy

(2013) Jens Friedrichs et al.   METHODS

Mechanical Activation of a Multimeric Adhesive Protein Through Domain Conformational Change

(2013) Sithara S. Wijeratne et al.   PHYSICAL REVIEW LETTERS

The Oxidative Modification of Von Willebrand Factor Is Associated with Thrombotic Angiopathies in Diabetes Mellitus

(2013) Laura Oggianu et al.   PLoS One

Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner

(2013) Erik Westein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-clotting-inspired reversible polymer–colloid composite assembly in flow

(2013) Hsieh Chen et al.   Nature Communications

ON THE VERSATILITY OF VON WILLEBRAND FACTOR

(2013) Peter Lenting   Mediterranean Journal of Hematology and Infectious Diseases

Highly Invasive Melanoma Cells Activate the Vascular Endothelium via an MMP-2/Integrin αvβ5–Induced Secretion of VEGF-A

(2012) Anna Desch et al.   AMERICAN JOURNAL OF PATHOLOGY

Direct Observation of von Willebrand Factor Elongation and Fiber Formation on Collagen During Acute Whole Blood Exposure to Pathological Flow

(2012) Thomas V. Colace et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

The unfolded von Willebrand factor response in bloodstream: the self-association perspective

(2012) Hailong Yuan et al.   Journal of Hematology & Oncology

Increased imaging speed and force sensitivity for bio-applications with small cantilevers using a conventional AFM setup

(2012) Michael Leitner et al.   MICRON

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

(2011) R. SCHNEPPENHEIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biology and physics of von Willebrand factor concatamers

(2011) T. A. SPRINGER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Elongational Flow Induces the Unfolding of von Willebrand Factor at Physiological Flow Rates

(2010) Charles E. Sing et al.   BIOPHYSICAL JOURNAL

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

von Willebrand factor promotes leukocyte extravasation

(2010) B. Petri et al.   BLOOD

The Mechanism of Melanoma-Associated Thrombin Activity and von Willebrand Factor Release from Endothelial Cells

(2010) Nina Kerk et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Plasma levels of von Willebrand factor in the etiologic subtypes of ischemic stroke

(2010) E. HANSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A mechanically stabilized receptor–ligand flex-bond important in the vasculature

(2010) Jongseong Kim et al.   NATURE

Shear-induced interaction of platelets with von Willebrand factor results in glycoprotein Ibα shedding

(2009) Hong Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Fluid Shear Induces Conformation Change in Human Blood Protein von Willebrand Factor in Solution

(2009) Indrajeet Singh et al.   BIOPHYSICAL JOURNAL

Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13

(2009) J. Chen et al.   BLOOD

Differential Effect of Extracellular Acidosis on the Release and Dispersal of Soluble and Membrane Proteins Secreted from the Weibel-Palade Body

(2009) Victor Babich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

Structural organization of Weibel-Palade bodies revealed by cryo-EM of vitrified endothelial cells

(2009) J. A. Berriman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Integrin  v 3 on human endothelial cells binds von Willebrand factor strings under fluid shear stress

(2008) J. Huang et al.   BLOOD

Selective release of molecules from Weibel-Palade bodies during a lingering kiss

(2008) V. Babich et al.   BLOOD

The vessel wall and its interactions

(2008) D. D. Wagner et al.   BLOOD

Function of von Willebrand factor in haemostasis and thrombosis

(2008) A. J. REININGER   HAEMOPHILIA

ADAMTS13: a new link between thrombosis and inflammation

(2008) Anil K. Chauhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack

(2008) J. T. B. CRAWLEY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Diagnostic workup of patients with acquired von Willebrand syndrome: a retrospective single-centre cohort study

(2008) A. TIEDE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

VWF attributes – impact on thrombus formation

(2008) Armin J. Reininger   THROMBOSIS RESEARCH

N-linked glycosylation of VWF modulates its interaction with ADAMTS13

(2007) T. A. J. McKinnon et al.   BLOOD

Formation and function of Weibel-Palade bodies

(2007) D. J. Metcalf et al.   JOURNAL OF CELL SCIENCE