Hepatitis C Virus Adaptation to T-Cell Immune Pressure

Susceptibility to chronic hepatitis C virus infection is influenced by sequence differences in immunodominant CD8+ T cell epitopes

(2012) Susanne Ziegler et al.   JOURNAL OF HEPATOLOGY

Next generation deep sequencing and vaccine design: today and tomorrow

(2012) Fabio Luciani et al.   TRENDS IN BIOTECHNOLOGY

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

(2011) K. Fitzmaurice et al.   GUT

Constrained Pattern of Viral Evolution in Acute and Early HCV Infection Limits Viral Plasticity

(2011) Katja Pfafferott et al.   PLoS One

Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection

(2011) Rowena A. Bull et al.   PLoS Pathogens

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Effect of immune pressure on hepatitis C virus evolution: Insights from a single-source outbreak

(2010) Shahzma Merani et al.   HEPATOLOGY

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure

(2009) Andri Rauch et al.   HEPATOLOGY

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

(2009) Eva Dazert et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Host genetic determinants of spontaneous hepatitis C clearance

(2009) Andri Rauch et al.   PHARMACOGENOMICS

Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs

(2008) S. Salloum et al.   JOURNAL OF VIROLOGY

Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

(2008) Z. L. Brumme et al.   JOURNAL OF VIROLOGY

Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness

(2008) Luke Uebelhoer et al.   PLoS Pathogens