Article
Medicine, General & Internal
Maria Vlachou, Vasileios Kamperidis, Efthymia Vlachaki, Georgios Tziatzios, Despoina Pantelidou, Afroditi Boutou, Chrysa Apostolou, Despoina Papadopoulou, George Giannakoulas, Haralambos Karvounis
Summary: The study found that left atrial peak systolic strain was independently associated with atrial arrhythmia burden in patients with beta-thalassemia major, regardless of the duration of blood transfusions and CMR T2*.
Article
Medicine, General & Internal
Maria Pina Dore, Pier Sergio Saba, Giulia Tomassini, Caterina Niolu, Marco Monaco, Giovanni Mario Pes
Summary: A retrospective study showed that long-lasting H. pylori infection is independently associated with hypertension and carotid lesions. Further validation from prospective studies is needed.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mu Chen, Jian Sun, Qun-Shan Wang, Peng-Pai Zhang, Wei Li, Rui Zhang, Bin-Feng Mo, Yi-Chi Yu, Xingxing Cai, Mei Yang, Xiao-Ming Lian, Yan Zhao, Changqi Gong, Yi Yu, Bo Liu, Xiangfei Feng, Qiufen Lu, Yi-Gang Li
Summary: This study evaluated the procedural safety and long-term outcome of the combined procedure of catheter ablation and left atrial appendage closure in patients with atrial fibrillation. The results showed that the combined procedure was safe and effective in controlling heart rhythm and reducing the risk of strokes.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jean-Baptiste Guichard, Feng Xiong, Xiao-Yan Qi, Nathalie L'Heureux, Roddy Hiram, Jiening Xiao, Patrice Naud, Jean-Claude Tardif, Antoine Da Costa, Stanley Nattel
Summary: This study assessed the specific contributions of atrial fibrillation-related atrial arrhythmia vs. associated ventricular arrhythmia to remodeling. The results showed that both atrial tachyarrhythmia and rapid ventricular response during AF produce distinct atrial remodelling, providing new insights into AF-related remodeling and ventricular rate-control considerations.
CARDIOVASCULAR RESEARCH
(2021)
Article
Multidisciplinary Sciences
Yun Gi Kim, Yun Young Choi, Kyung-Do Han, Kyongjin Min, Ha Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim
Summary: The study found that patients with new-onset AF have a higher risk of developing VT, VFL, and VF, and the incidence of various ventricular arrhythmias significantly increases. The potential risk of suffering lethal ventricular arrhythmia in individuals with AF should be taken into consideration in clinical practice.
SCIENTIFIC REPORTS
(2021)
Article
Pharmacology & Pharmacy
Chun-Chao Chen, Chun-Chih Chiu, Nai-Hsuan Chen, Tsung-Yeh Yang, Cheng-Hsin Lin, Yu-Ann Fang, William Jian, Meng-Huan Lei, Hsien-Tang Yeh, Min-Huei Hsu, Wen-Rui Hao, Ju-Chi Liu
Summary: This study found that influenza vaccination is associated with a lower risk of atrial fibrillation in patients with gout, and the protective effect seems to depend on the number of vaccine doses given.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Pawel Balsam, Piotr Lodzinski, Monika Gawalko, Leszek Kraj, Andrzej sliwczynski, Cezary Maciejewski, Bartosz Krzowski, Agata Tyminska, Krzysztof Ozieranski, Marcin Grabowski, Janusz Bednarski, Grzegorz Opolski
Summary: This study aimed to compare long-term outcomes in Polish patients with atrial fibrillation based on oral anticoagulation type, showing that VKA and rivaroxaban were associated with a significant increase in the risk of hemorrhagic events compared to dabigatran. The available thromboembolic and bleeding risk scores showed poor prediction value in this cohort.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Clara Stegmann, Cosima Jahnke, Frank Lindemann, Sabrina Oebel, Sergio Richter, Andreas Bollmann, Nikolaos Dagres, Gerhard Hindricks, Ingo Paetsch
Summary: This study aimed to establish a predictive model based on CMR for distinguishing 'arrhythmia-induced' from 'arrhythmia-mediated' cardiomyopathy in patients with atrial tachyarrhythmias. Results showed that assessment of LVEDVI category and LGE by CMR allowed for effective identification of arrhythmia-induced cardiomyopathy.
Article
Cardiac & Cardiovascular Systems
Xiya Lu, Zhijing Wang, Liu Yang, Changqing Yang, Meiyi Song
Summary: In this study, age and ascites were confirmed to be risk factors associated with atrial arrhythmia in patients with liver cirrhosis.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Tomas Forslund, Frieder Braunschweig, Martin J. Holzmann, Anwar J. Siddiqui
Summary: Acute electrical cardioversion is associated with a higher unadjusted risk for stroke compared to elective cardioversion, but the risk becomes similar after adjustment for anticoagulant treatment. This study highlights the importance of anticoagulation before electrical cardioversion according to recent European guidelines.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Cherry Alexander, Martin J. Bishop, Rebecca J. Gilchrist, Francis L. Burton, Godfrey L. Smith, Rachel C. Myles
Summary: This study demonstrates that activation of L-type calcium channels (LTCC) at sites displaying steep voltage gradients generates premature ventricular complexes (PVCs) which induce polymorphic ventricular tachycardia (TdP), providing a mechanism and rationale for using LTCC blockers as a novel therapeutic approach in long QT syndrome (LQTS).
CARDIOVASCULAR RESEARCH
(2023)
Review
Dermatology
Hsuan Chia Yang, Tahmina Nasrin Poly, Md. Mohaimenul Islam, Bruno Andreas Walther, Chieh-Chen Wu
Summary: Several epidemiological studies have shown that psoriasis increases the risk of developing atrial fibrillation but evidence of this is still scarce. This study systematically reviewed and synthesized the evidence, concluding that psoriasis is significantly associated with an increased risk of developing atrial fibrillation. Physicians should monitor patients' physical condition on a timely basis.
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Grzegorz Warminski, Piotr Urbanek, Michal Orczykowski, Robert Bodalski, Lukasz Kalinczuk, Kamil Zielinski, Gary S. Mintz, Zbigniew Jedynak, Andrzej Hasiec, Joanna Zakrzewska-Koperska, Ilona Michalowska, Ilona Kowalik, Hubert Lazarczyk, Maciej Sterlinski, Maria Bilinska, Pawel Plawiak, Lukasz Szumowski
Summary: The coexistence of left atrial enlargement and increased left ventricular wall thickness is associated with the highest rate of arrhythmia recurrence after cryo-balloon-based pulmonary vein isolation for atrial fibrillation.
KARDIOLOGIA POLSKA
(2022)
Article
Cardiac & Cardiovascular Systems
Erika Hutt, Maria Vega Brizneda, Ghazaleh Goldar, Jose Aguilera, Tom Kai Ming Wang, Ziad Taimeh, Daniel Culver, Thomas Callahan, W. H. Wilson Tang, Paul C. Cremer, Wael A. Jaber, Manuel L. Ribeiro Neto, Christine L. Jellis
Summary: In patients with cardiac sarcoidosis, a mild reduction in left ventricular ejection fraction (LVEF) of 42% was identified as the optimal cutoff for predicting ventricular arrhythmia (VA) and all-cause mortality. Prior occurrence of VA and the presence of scar in cardiac magnetic resonance (CMR) or positron emission tomography (PET) are strong risk factors for future VA and mortality.
Article
Cardiac & Cardiovascular Systems
Alexandra S. Mighiu, Alice Recalde, Klemen Ziberna, Ricardo Carnicer, Jakub Tomek, Gil Bub, Alison C. Brewer, Sander Verheule, Ajay M. Shah, Jillian N. Simon, Barbara Casadei
Summary: NOX2 plays a significant role in AF, while NOX2 overexpression does not affect the electrical and structural properties of atrial myocardium.
CARDIOVASCULAR RESEARCH
(2021)
Article
Dermatology
Theodosios Bisdas, Nikolaos Patelis, Georgia Argyrakopoulou, Dimitrios Tsiachris, Aristotelis Kurtis, Panagiotis Gargalianos-Kakoliris, Christodoulos Stefanadis
Summary: The complexity of critical limb ischemia (CLI) requires a dedicated multidisciplinary team for treatment. This study aimed to assess the effectiveness of referring CLI patients scheduled for major amputation elsewhere to a dedicated CLI center. The analysis showed that patients in severe stages of CLI who received a second opinion from a dedicated multidisciplinary team had high limb salvage and survival rates after major amputation.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2022)
Review
Immunology
Joshua Adedeji Bolarin, Mercy Adaramodu Oluwatoyosi, Joshua Iseoluwa Orege, Emmanuel Ayodeji Ayeni, Yusuf Ajibola Ibrahim, Sherif Babatunde Adeyemi, Bashir Bolaji Tiamiyu, Lanre Anthony Gbadegesin, Toluwanimi Oluwadara Akinyemi, Chuks Kenneth Odoh, Happiness Ijeoma Umeobi, Adenike Bernice-Eloise Adeoye
Summary: This review outlines the usage of antiviral drugs, antibiotics, and immune-stimulants in managing SARS-CoV-2, as well as discussing potential drug interactions and monitoring methods.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Panagiota Pietri, Christodoulos Stefanadis
Summary: Cardiovascular aging and longevity are interconnected through various pathophysiological mechanisms, with factors like cardiometabolic disorders and genetic modulators playing significant roles. Understanding the genetic, molecular, and biochemical pathways of aging may lead to interventions that delay cardiovascular aging, potentially contributing to achieving longevity goals. Research on long-living populations helps translate these mechanisms into clinical data for further study.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
History & Philosophy Of Science
Matthew Adamson, Roberto Lalli
Summary: The contemporary scholarship on science diplomacy is turning to historical approaches to gain insights with the unique tools historians of science provide. Through historical studies, it is evident that science diplomacy has historically mediated the circulation of technoscientific knowledge and materials in both the Global South and North.
Letter
Cardiac & Cardiovascular Systems
Panagiota Pietri, George Georgiopoulos, Christodoulos Stefanadis
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Nutrition & Dietetics
Alexandra Foscolou, Christina Chrysohoou, Kyriakos Dimitriadis, Konstantina Masoura, Georgia Vogiatzi, Viktor Gkotzamanis, George Lazaros, Costas Tsioufis, Christodoulos Stefanadis
Summary: This study aimed to evaluate the sociodemographic, lifestyle, and clinical characteristics of Ikarian islanders and identify healthy aging trajectories of multimorbidity. The results showed that multimorbidity was negatively correlated with a healthy aging index (HAI), with a 20% lower odds of multimorbidity for every 10-unit increase in HAI. Multimorbidity trends in relation to HAI varied between men and women at different ages, converging only in the seventh decade of life.
Article
Pharmacology & Pharmacy
Dimitris Tsiachris, Ioannis Doundoulakis, Panagiotis Tsioufis, Eirini Pagkalidou, Christos-Konstantinos Antoniou, Stefanos M. Zafeiropoulos, Konstantinos A. Gatzoulis, Konstantinos Tsioufis, Christodoulos Stefanadis
Summary: This systematic review compares the effectiveness and safety of class Ic agents for cardioversion of paroxysmal AF and finds that intravenous flecainide is the most effective option. Class Ic agents appear to be safe for pharmacologic cardioversion of AF regardless of the presence of SHD.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Endocrinology & Metabolism
Sincer Abide, Kaygusuz Tuba, Alkan Yunus, Cosgun Mehmet, Dogan Umit, Ulas Fatih, Gunes Yilmaz, Isa Sincer
Summary: The study found that epicardial fat thickness and monocyte count to high density lipoprotein ratio showed significant changes in diabetic retinopathy. Epicardial fat thickness may be a predictor for the presence of proliferative DR.
INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES
(2023)
Article
Economics
Jay Pil Choi, Christodoulos Stefanadis
Summary: This article examines tippy network markets that allow price discrimination and finds that under certain conditions, network competition may lead to a unique subgame-perfect equilibrium where the winner's identity is fully determined by its product features. The concept of the dominant value margin is introduced as a metric for the effectiveness of divide-and-conquer strategies. However, the outcome of a market where suppliers with larger dominant value margins can sell to all customers does not necessarily result in social efficiency.
INTERNATIONAL ECONOMIC REVIEW
(2022)
Letter
Cardiac & Cardiovascular Systems
Christodoulos Stefanadis, Christina Chrysohoou, Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Panagiota Manolakou, Gerasimos Siasos, Konstantinos Tsioufis, George Panagiotakopoulos, Theoklis Zaoutis, Demosthenes Panagiotakos
HELLENIC JOURNAL OF CARDIOLOGY
(2022)
Letter
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Grigorios Chatzantonis, Christos-Konstantinos Antoniou, Haris Lalos, Gregory C. Bogdanis, Pantelis Nikolaou, Anastasios Spanos, Stefanos Karagiannis, Costas Tsiou, Ali Yilmaz, Christodoulos Stefanadis
HELLENIC JOURNAL OF CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Zafer Kok, Isa Sincer, Yilmaz Gunes, Ulku Mete UraI
Summary: This study assessed atrial conduction time and P-wave dispersion in patients with gestational diabetes mellitus (GDM) and compared them to a healthy pregnant control group. The results showed that GDM patients had higher P-wave dispersion and atrial conduction and electromechanical delay times compared to the control group. In addition, there was a positive correlation between intra-atrial delay time and P-wave dispersion in the GDM group.
INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES
(2023)
Review
Cardiac & Cardiovascular Systems
Dimitris Tsiachris, Ioannis Doundoulakis, Christos-Konstantinos Antoniou, Eirini Pagkalidou, Stefanos Zafeiropoulos, Athanasios Kordalis, Konstantinos A. Gatzoulis, Gian-Battista Chierchia, Carlo de Asmundis, Konstantinos Tsioufis, Christodoulos Stefanadis
Summary: This study conducted a systematic review and meta-analysis to evaluate the effectiveness and safety of a time to isolation (TTI)-based strategy of cryoballoon ablation (CBA) in the treatment of atrial fibrillation. The results suggest that an individualized CBA dosing strategy based on TTI and extended duration of CBA can reduce recurrence post-AF ablation and decrease procedure time and incidence of phrenic nerve palsy.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Ioannis Doundoulakis, Panagiota Manolakou, Athanasios Kordalis, Dimitrios Konstantinou, Konstantinos Gatzoulis, Konstantinos Tsioufis, Christodoulos Stefanadis
Summary: This study compared the clinical outcomes of a three-dimensional electroanatomical mapping (3D-EAM)-based strategy targeting slow pathway (SP) elimination with the conventional fluoroscopic approach in atrioventricular node reentrant tachycardia (AVNRT) ablation. The results showed that 3D-EAM improved procedural parameters, reduced fluoroscopy time and dose, and increased SP elimination frequency. Follow-up results demonstrated lower recurrence rates and redo procedure rates in the 3D-EAM-based group.
JOURNAL OF ARRHYTHMIA
(2022)
Review
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Ioannis Doundoulakis, Panagiota Manolakou, Demetrios Sougiannis, Athanasios Kordalis, Konstantinos A. Gatzoulis, Gian-Battista Chierchia, Carlo de Asmundis, Christodoulos Stefanadis, Konstantinos Tsioufis
Summary: Nowadays, cryoballoon (CB) has become an established alternative to radio frequency (RF) ablation for pulmonary vein isolation (PVI), with the ability to isolate PVs in a single application. In a study on over 1000 consecutive patients, our center optimized the CB PVI procedure. It is expected that future guidelines will recommend CB as the first-line PVI for patients with paroxysmal AF and a class I indication. In a long-term follow-up of the EARLY-AF trial, CB showed a lower incidence of persistent atrial fibrillation compared to anti-arrhythmic drugs.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
