Article
Medicine, General & Internal
Yueting Ma, Yongdong Lin, Yuancun Li, Zhuoyi Hu, Kunliang Qiu
Summary: The purpose of this study was to compare the measurement accuracy of new/updated intraocular lens power calculation methods with existing methods in Chinese eyes. The results showed that the Barrett Universal II formula had the lowest absolute error and median absolute error among the tested formulas, and there was no significant difference in postoperative refractive prediction among all the formulas.
FRONTIERS IN MEDICINE
(2023)
Article
Multidisciplinary Sciences
Ayoung Choi, Hyunggoo Kwon, Sohee Jeon
Summary: This study evaluated the accuracy of different IOL formulas for Acrysof IQ Panoptix TFNT IOL implantation, with Barrett Universal II performing best in the overall study population but poorly in short AXL eyes, especially with higher astigmatism, wider WTW, and shorter AXL.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Huanhuan Cheng, Li Wang, Jack X. Kane, Jianbing Li, Liangping Liu, Mingxing Wu
Summary: This study compares the accuracy of different artificial intelligence formulas in highly myopic and extremely myopic eyes, with the Kane formula showing superior performance. Additionally, in extremely myopic eyes, the Kane formula outperforms the RBF 2.0, BUII, and Haigis methods.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Er Mo, Zexin Chen, Ke Feng, Fuman Yang, Jin Li, Yun-e Zhao
Summary: This study evaluated the accuracy of newer online intraocular lens (IOL) formulas in extremely elongated eyes. The EVO 2.0 and K6 formulas were recommended for IOL power calculation in extreme myopia cases. Caution should be taken when using modern artificial intelligence-based formulas for eyes with axial length longer than 32 mm or meniscus IOLs.
JOURNAL OF REFRACTIVE SURGERY
(2023)
Article
Medicine, General & Internal
Majid Moshirfar, Kathryn M. Durnford, Jenna L. Jensen, Daniel P. Beesley, Telyn S. Peterson, Ines M. Darquea, Yasmyne C. Ronquillo, Phillip C. Hoopes
Summary: This study aimed to compare the accuracy of various IOL power calculation formulas in long eyes, finding that the SRK/T formula with CMAL adjustment had the highest accuracy within +/- 0.50 D range, while Holladay 1 had lower predictive accuracy with AL adjustment.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Oleksiy V. Voytsekhivskyy, Larysa Tutchenko, Diogo Hipolito-Fernandes
Summary: This study compared the accuracy of intraocular lens power formulas in eyes with an axial length of 22mm or less. The results showed that VRF-G, Haigis, and Kane were the most accurate predictors of postoperative refraction, while the Barrett formula was less predictable.
Article
Medicine, General & Internal
Tong Sun, Yiyun Liu, Xiaorui Zhao, Yufei Gao, Tingting Yang, Qianqian Lan, Chuhao Tang, Hong Qi
Summary: This study compared the performance of a diffractive trifocal intraocular lens in eyes with different axial lengths. The results showed that the trifocal IOL provided satisfactory visual outcomes for patients with different axial lengths, but patients with long axial lengths may face difficulties in near activities.
FRONTIERS IN MEDICINE
(2022)
Article
Optics
Monica Malaescu, Bogdana Tabacaru, Mihnea Munteanu, Leila Al Barri, Adriana Stanila, Horia Tudor Stanca
Summary: This study aimed to compare the accuracy of four commonly used intraocular lens calculation formulas in two types of monofocal implants and found that the Barrett Universal II formula showed good performance in different axial lengths and can be used even without lens constant optimization.
Article
Ophthalmology
Lei Lin, Mengxiang Xu, Er Mo, Shenghai Huang, Xiaoliang Qi, Siyi Gu, Weijie Sun, Qiudong Su, Jin Li, Yun-e Zhao
Summary: The study compared the accuracy of five formulas for intraocular lens power calculation in patients with high axial myopia. The EVO 2.0 and Kane formulas performed better in patients with long axial length, while the SRK/T formula showed poorer outcomes in patients with long and super long axial length.
JOURNAL OF REFRACTIVE SURGERY
(2021)
Article
Oncology
Zhouyue Li, Zhangkai Lian, Charlotte Aimee Young, Jing Zhao, Guangming Jin, Danying Zheng
Summary: The study analyzed the accuracy and performance of different IOL calculation formulas in predicting postoperative refractive prediction error in patients with inadequate capsular support, finding that the SRK/T formula may be the best choice, especially in cases with extremely large or small keratometry and axial length.
ANNALS OF TRANSLATIONAL MEDICINE
(2021)
Review
Public, Environmental & Occupational Health
Yi Zhou, Minhui Dai, Lingyu Sun, Xiangyi Tang, Ling Zhou, Zhiyao Tang, Jian Jiang, Xiaobo Xia
Summary: This study systematically compared and ranked the accuracy of AI-based intraocular lens (IOL) power calculation formulas and traditional IOL formulas in highly myopic eyes. The network meta-analysis showed that AI-based formulas, such as XGBoost, Hill-RBF, and Kane, were more accurate than traditional formulas.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Ophthalmology
Pingjun Chang, Shuyi Qian, Yalan Wang, Siyan Li, Fuman Yang, Yiwen Hu, Zhuohan Liu, Yun-e Zhao
Summary: This study aimed to investigate the characteristics of eyes with large variations in predicted refraction using four traditional intraocular lens formulas and evaluate the accuracy of new-generation intraocular lens power calculation formulas. The results showed that the new-generation formulas had lower median absolute errors compared to the traditional formulas, indicating higher accuracy.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
Miki Omoto, Kaoruko Sugawara, Hidemasa Torii, Erisa Yotsukura, Sachiko Masui, Yuta Shigeno, Yasuyo Nishi, Kazuno Negishi
Summary: The aim of this study was to investigate the prediction accuracy of intraocular lens (IOL) power formulas with artificial intelligence (AI) for high myopia. The results showed that the prediction formulas using AI had excellent prediction accuracy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Chenxi Yan, Ke Yao
Summary: The study investigated the impact of preoperative lens vault on the accuracy of various formulas in eyes with a shallow anterior chamber. It was found that the Barrett and Kane formulas showed higher accuracy in different subgroups, while the Haigis and Hoffer QST formulas may have larger prediction errors in eyes with a large lens vault.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Ming-Hui Deng, Xiao-Gang Wang, Song Chen, Xue-Feng Shi
Summary: The study investigated the difference in binocular intraocular lens (IOL) power based on the axial length (AL) of the eye using the Lenstar LS 900 optical biometry. The findings showed that more than half of the participants with long AL had a binocular IOL power difference of more than 0.50 D.
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Jin Jing, Shen Yinchen, Chen Xia, Wang Jing, Chen Chong, Xu Xun, Huang Hengye, Liu Kun
Article
Genetics & Heredity
Chong Chen, Qiao Sun, Mingmin Gu, Tianwei Qian, Dawei Luo, Kun Liu, Xun Xu, Suqin Yu
MOLECULAR GENETICS & GENOMIC MEDICINE
(2020)
Article
Pharmacology & Pharmacy
Lu Cheng, Chong Chen, Wenke Guo, Kun Liu, Qianqian Zhao, Ping Lu, Fudong Yu, Xun Xu
Summary: This study identified EFEMP1 as a potential novel biomarker for choroidal neovascularization in age-related macular degeneration (AMD), particularly in wet AMD patients. The overexpression of EFEMP1 was associated with increased angiogenesis, while knockdown of EFEMP1 led to decreased tube formation and proliferation in endothelial cells. These findings suggest that EFEMP1 could be a promising target for the development of pharmaceuticals and diagnostics for wet AMD.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Ophthalmology
Xieyi Yao, Chong Chen, Jian Zhang, Yupeng Xu, Shuyu Xiong, Qing Gu, Xun Xu, Yan Suo
Summary: The novel peptide NT/K-CFY effectively inhibits neovascularization in vitro and in vivo, demonstrating potential therapeutic efficacy for ocular angiogenesis-related diseases. Furthermore, NT/K-CFY peptide also improves retinal blood perfusion and shows promising results in inhibiting angiogenesis, highlighting its potential application value.
CURRENT EYE RESEARCH
(2021)
Article
Ophthalmology
Xieyi Yao, Chong Chen, Jian Zhang, Yupeng Xu, Shuyu Xiong, Qing Gu, Xun Xu, Yan Suo
Summary: This study assessed the anti-neovascularization effect of a novel peptide NT/K-CRS in vitro and in vivo, showing that the peptide effectively inhibited new blood vessel formation with minor effects on cell proliferation and viability, indicating its potential therapeutic value for neovascular-related ocular diseases.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
(2021)
Article
Oncology
Jingfa Zhang, Qinghua Qiu, Haiyan Wang, Chong Chen, Dawei Luo
Summary: The increased permeability of retinal capillary endothelial cells is a key feature in the progression of diabetic retinopathy. Mechanistic insights into the involvement of TRIM46 and GPX4 in regulating ferroptosis of HRCECs provide potential therapeutic targets for the treatment of DR.
EXPERIMENTAL CELL RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Minjiao Zhu, Haiyang Liu, Wenjiao Cao, Yuefei Fang, Zheng Chen, Xinming Qi, Dawei Luo, Chong Chen
Summary: Cell-penetrating peptides (CPPs) play an important role in drug delivery, but their mechanisms of penetration are not well understood. This study investigated the effects of different endocytosis inhibitors on the uptake of CPPs and found that they predominantly localize in the lysosome. The uptake of CC12 and penetratin was influenced by various inhibitors.
JOURNAL OF PEPTIDE SCIENCE
(2022)
Article
Ophthalmology
Tianwei Qian, Chong Chen, Caihua Li, Qiaoyun Gong, Kun Liu, Gao Wang, Isabelle Schrauwen, Xun Xu
Summary: This study identified a genetic defect in a Chinese family with congenital aniridia combined with cataract and nystagmus. Through comprehensive ophthalmic examinations and genome sequencing, a novel deletion in the PAX6 gene associated with the disease was detected, expanding the understanding of genetic defects linked to congenital aniridia.
Article
Ophthalmology
Yihan Wang, Junwei Fang, Tian Niu, Xindan Xing, Hanying Wang, Xin Shi, Yujuan Liu, Xinyi Liu, Chong Chen, Kun Liu
Summary: This study investigated the predictive role of serum angiopoietin-1 and angiopoietin-2 (Ang-1/Ang-2) in evaluating the severity of diabetic retinopathy (DR). The results showed that the Ang-1/Ang-2 ratio can serve as a biomarker and early warning sign for DR diagnosis.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Medicine, Research & Experimental
Tianwei Qian, Qiaoyun Gong, Chong Chen, Xia Wu, Lin Xue, Ying Fan, Weijun Wang, Zhihua Zhang, Hui Cao, Xun Xu
Summary: This study aims to evaluate the efficacy and safety of diazepam for intraoperative blood pressure (BP) stabilisation in hypertensive patients undergoing vitrectomy with retrobulbar anaesthesia. The trial will compare the effectiveness of diazepam and placebo in controlling systolic BP during surgery, as well as assess the occurrence of adverse reactions post-surgery. The results of this trial will provide important insights into the use of diazepam in maintaining BP stability during vitrectomy in patients with a history of hypertension.
Article
Pharmacology & Pharmacy
Yinchen Shen, Hanying Wang, Xiaoyin Xu, Chong Chen, Shaopin Zhu, Lu Cheng, Junwei Fang, Kun Liu, Xun Xu
Summary: This study investigated the relationship between serum metabolome and treatment response to anti-VEGF therapy in nAMD and PCV patients. The study found that metabolites such as LPC and diacylglycerophosphocholine impact the response to conbercept treatment, with LPC 18:0 identified as a potential biomarker to discriminate responders from non-responders. The findings suggest that metabolites may be useful for guiding treatment options in nAMD and PCV.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Ophthalmology
Tianwei Qian, Yan Suo, Yingyan Ma, Chong Chen, Kun Liu, Feng'e Chen, Ying Fan, Weijun Wang, Xun Xu
Summary: This study compared the anatomical outcomes of air and C3F8 tamponade in pars plana vitrectomy for rhegmatogenous retinal detachment. The results showed that air had equivalent effects to C3F8, with a shorter period to intraocular bubble disappearance, less risk of post-operative intraocular hypertension, and lower cost.
OPHTHALMIC RESEARCH
(2023)
Editorial Material
Ophthalmology
Chong Chen, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2023)
Article
Ophthalmology
Chong Chen, Xia Chen, Hengye Huang, Changjing Han, Yuan Qu, Huiyi Jin, Tian Niu, Yuan Zhang, Kun Liu, Xun Xu
ACTA OPHTHALMOLOGICA
(2019)
Article
Engineering, Biomedical
Chong Chen, Kun Liu, Yupeng Xu, Pengwei Zhang, Yan Suo, Yi Lu, Wenyuan Zhang, Li Su, Qing Gu, Huamao Wang, Jianren Gu, Zonghai Li, X. Xu
