Article
Agriculture, Dairy & Animal Science
Xiaoqing Pan, Xinglong Wang, Le Shao, Jie Yang, Feng Qin, Jian Li, Xia Zhang, Pin Zhai
Summary: This study analyzed the effects of light color on rabbit reproductive performance and the expression of key follicular development genes. The results showed that red light and white light increased the conception rate, kindling rate, and total litter size at birth. Red light had a greater impact on litter size and weight at weaning compared to green and blue light. Red light also had a greater effect on live litter size at birth compared to blue light. Green and blue light reduced the number of secondary and tertiary follicles compared to white light. Red light also resulted in greater expression of certain genes related to follicular development compared to white light, green light, and blue light.
JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY
(2022)
Article
Veterinary Sciences
Mojtaba Kafi, Mehran Ghaemi, Mehdi Azari, Abdolah Mirzaei, Samad Azarkaman, Yusof Torfi
Summary: The study showed that cows with subclinical endometritis (SCE) had lower oocyte maturation and fertilization rates compared to normal heifers (NH), with FF from repeat breeder cows resulting in less oocyte maturation and cumulus cell expansion. The lower fertility in repeat breeder cows could be attributed to the lower oocyte maturation rate and lower expression of GDF9, StAR, and FSHr in the cumulus-oocyte complexes.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Endocrinology & Metabolism
Pavine L. C. Lefevre, Thomas C. Nardelli, Weon-Young Son, Amy R. Sadler, Dorothea F. K. Rawn, Cindy Goodyer, Bernard Robaire, Barbara F. Hales
Summary: Overall, exposure to PBDEs was found to be associated with dysregulation of gene expression pathways essential for ovulation. Mural granulosa cells were more sensitive to PBDE exposure compared to cumulus cells, and exposure to different PBDE congeners resulted in distinct gene expression changes related to innate immunity and inflammation pathways.
Review
Cell Biology
Jitender K. Bhardwaj, Aakansha Paliwal, Priyanka Saraf, Som N. Sachdeva
Summary: Follicular development and maintenance of the primordial follicle pool play a crucial role in the reproductive lifespan of an organism, with autophagy serving as a key regulatory mechanism. Dysregulation or mutation of autophagy-related genes can significantly impact follicular development and, consequently, female reproductive health. Various signaling pathways are involved in regulating autophagy in granulosa and oocytes, with mTOR signaling being a primary mechanism.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Oncology
Sabrina Kalmbach, Michael Grau, Myroslav Zapukhlyak, Ellen Leich, Vindi Jurinovic, Eva M. Hoster, Annette S. Staiger, Katrin Kurz, Oliver Weigert, Erik Gaitzsch, Verena Passerini, Marianne Engelhard, Klaus Herfarth, Klaus Beiske, Francesca Micci, Peter Moeller, Heinz-Wolfram C. Bernd, Alfred Feller, Wolfram Klapper, Harald Stein, Martin-Leo Hansmann, Sylvia Hartmann, Martin Dreyling, Harald Holte, Georg Lenz, Andreas Rosenwald, German Ott, Heike Horn, German Lymphoma Alliance GLA
Summary: Comprehensive analysis of localized follicular lymphoma (lFL) and systemic follicular lymphoma (sFL) revealed overlapping genetic and chromosomal abnormalities. However, significant differences were found in the frequency of chromosomal alterations, specifically in 18q gains. Rare gains in 18q21 were associated with inferior progression-free survival in lFL. ARID1A mutations were more frequently detected in sFL compared to lFL. This study provides novel insights and identifies 18q21 gains as a prognostic marker in lFL.
Article
Agriculture, Dairy & Animal Science
Gabriela H. Pedroza, Lawrence F. Lanzon, Maria B. Rabaglino, Wendy L. Walker, Payam Vahmani, Anna C. Denicol
Summary: Negative energy balance in the postpartum period can lead to reduced fertility in dairy cows. This study found that elevated non-esterified fatty acids (NEFA) levels during negative energy balance can cause accumulation of fatty acids in the ovarian tissue and preantral follicles, resulting in changes in ovarian gene expression and a response to injury. These findings provide further understanding of the potential links between metabolic imbalance and infertility.
ANIMAL REPRODUCTION SCIENCE
(2022)
Article
Entomology
Qiu-Li Hou, Er-Hu Chen, Yi-Fei Xie, Wei Dou, Jin-Jun Wang
Summary: Transcriptome analysis of ovary development in Bactrocera dorsalis revealed the crucial role of the BdNanos gene, knocking down of which significantly inhibited ovary development, highlighting its importance in the reproductive process of B. dorsalis.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2021)
Article
Integrative & Complementary Medicine
Jing Zhou, Ping Yin, Qingyi Zhao, Zhihai Hu, Yi Wang, Guizhi Ma, Xinyi Wu, Lu Lu, Yin Shi
Summary: Electroacupuncture improved follicular development and metabolism and regulated the expression levels of adiponectin, AMPK alpha 1, LKB1 and ACC in our obese rat model of PCOS.
ACUPUNCTURE IN MEDICINE
(2023)
Article
Environmental Sciences
Jingyi Song, Xiaochen Ma, Feixue Li, Jing Liu
Summary: This study found that gestational exposure of female mice to multiple pyrethroids at recommended safe doses had irreversible adverse effects on the ovaries in female offspring. The exposure regulated the expression of miRNAs during early developmental stages, disrupting key biological processes and signaling pathways governing follicular development and ovarian functions. However, lactational and peripubertal exposure to pyrethroid mixture did not significantly affect follicular development and ovarian functions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Yu Jin Kim, YoungJoon Park, Yeo Reum Park, Young Sang Kim, Hye Ran Lee, Sang Jin Lee, Myung Joo Kim, KyuBum Kwack, Jung Jae Ko, Jae Ho Lee
Summary: The neogenin ligand RGMc promotes follicular development in the ovaries via the PGD2 signaling pathway, potentially offering a treatment approach for patients with a POR.
Review
Reproductive Biology
Hong Zhao, Yifu Wang, Yihua Yang
Summary: Follicular development is a crucial process that determines the number of oocytes and its dysregulation can lead to infertility and reproductive disorders. Traditional methods have been used to study follicular development at the tissue level, but the advent of single-cell techniques has allowed for the discovery of unique molecular mechanisms within individual cells. This review summarizes the achievements and limitations of traditional methods and focuses on understanding the physiological process and pathological mechanisms of follicular development at the single-cell level.
BIOLOGY OF REPRODUCTION
(2023)
Article
Reproductive Biology
Lucas Oliveira e Silva, Alessio Valenza, Rodrigo Lemos Olivieri Rodrigues Alves, Mateus Anastacio da Silva, Taynara Jaqueline Barreiro da Silva, Jessica Cristina Lemos Motta, Jessica Nora Drum, Guilherme Madureira, Alexandre Henryli de Souza, Roberto Sartori
Summary: This study evaluated the progesterone release profiles of different commercial intravaginal devices and their effects on the development of the dominant follicle in non-lactating Holstein cows. The circulating progesterone concentrations produced by the devices were found to influence the growth rate of the dominant follicle during the treatment period.
Article
Reproductive Biology
Junpeng Yao, Hao Du, Hai Zhou, Xiaoqian Leng, Jinping Wu, Shan He, Jiang Luo, Xufang Liang, Hong Liu, Qingchao Wang, Qiwei Wei, Qingsong Tan
Summary: The ovarian development of Chinese sturgeon is affected by dietary lipid levels, with six key genes playing crucial roles in vitellogenic deposition and hydrolysis.
Article
Endocrinology & Metabolism
Adana A. M. Llanos, John B. Aremu, Ting-Yuan David Cheng, Wenjin Chen, Marina A. Chekmareva, Elizabeth M. Cespedes Feliciano, Bo Qin, Yong Lin, Coral Omene, Thaer Khoury, Chi-Chen Hong, Song Yao, Christine B. Ambrosone, Elisa V. Bandera, Kitaw Demissie
Summary: Increased body fatness is associated with higher LEP gene expression and LEPR protein expression in breast tumor tissues, with this association being more pronounced in White and postmenopausal women as well as ER+ cases.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biology
Tomoko Kawai, JoAnne S. Richards, Masayuki Shimada
Summary: Research has shown that through modulating processes such as DNA methylation levels and histone modifications, equine chorionic gonadotropin can promote the proliferation and differentiation of granulosa cells, and the timing and sequence of these epigenetic events are crucial for the progression of granulosa cell differentiation.
COMMUNICATIONS BIOLOGY
(2021)
Article
Clinical Neurology
Zohreh Ghotbeddin, Mohammad Reza Tabandeh, Mahdi Pourmahdi Borujeni, Fahimeh Fahimi Truski, Leila Tabrizian
ACTA NEUROLOGICA BELGICA
(2020)
Article
Reproductive Biology
Somayeh Shadmehr, Seyed Reza Fatemi Tabatabaei, Shima Hosseinifar, Mohammad Reza Tabandeh, Alireza Amiri
Article
Biochemistry & Molecular Biology
Mahmoud Hashemi Tabar, Mohammad Reza Tabandeh, Eskandar Moghimipour, Dian Dayer, Ata A. Ghadiri, Elham Allah Bakhshi, Mahmoud Orazizadeh, Mohammad Ali Ghafari
Article
Fisheries
Takavar Mohammadian, Mojtaba Alishahi, Mohammad Reza Tabandeh, Abdolhossein Jangaran Nejad, Esmaeil Karami, Mojtaba Zarea
AQUACULTURE INTERNATIONAL
(2019)
Article
Biotechnology & Applied Microbiology
Takavar Mohammadian, Abdolhossein Jangaran-Nejad, Mehrzad Mesbah, Tahereh Shirali, Pedram Malekpouri, Mohammad-Reza Tabandeh
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2020)
Article
Fisheries
Takavar Mohammadian, Mandieh Nasirpour, Mohammad Reza Tabandeh, Amir Ali Heidary, Reza Ghanei-Motlagh, Seyed Samad Hosseini
FISH & SHELLFISH IMMUNOLOGY
(2019)
Article
Veterinary Sciences
M. Basaki, M. R. Tabandeh, M. Aminlari, K. Asasi, E. Mohsenifard, B. Abdi-Hachesoo
Article
Fisheries
Mostafa Halimi, Mojtaba Alishahi, Mohammad Reza Abbaspour, Masoud Ghorbanpoor, Mohammad Reza Tabandeh
FISH & SHELLFISH IMMUNOLOGY
(2019)
Article
Fisheries
Takavar Mohammadian, Mandieh Nasirpour, Mohammad Reza Tabandeh, Mehrzad Mesbah
Article
Veterinary Sciences
Farideh Norvezh, Mohammad Razi Jalali, Mohammad Reza Tabandeh, Mohammad Rahim Haji Hajikolaei, Saad Gooraninejad
RESEARCH IN VETERINARY SCIENCE
(2019)
Article
Biochemistry & Molecular Biology
Mohammad Reza Tabandeh, Amal Sattar Taha, Hanaa Addai Ali, Mohammad Razijalali, Narges Mohammadtaghvaei
Summary: This study investigated the alterations of circulating adipocytokines in patients with type 2 diabetes mellitus (T2DM) coinciding with clinical and subclinical thyroid dysfunctions. The results showed that T2DM patients with clinical thyroid dysfunctions had higher levels of circulating adipocytokines and inflammatory factors compared to those with subclinical thyroid dysfunctions or without thyroid dysfunctions. These findings suggest that clinical thyroid dysfunction in T2DM patients is associated with elevated levels of circulating adipocytokines and inflammatory factors.
Article
Urology & Nephrology
Naeem Erfani Majd, Niloofar Sadeghi, Marziyeh Tavalaee, Mohammad Reza Tabandeh, Mohammad Hossein Nasr-Esfahani
Article
Cell Biology
Dian Dayer, Mohammad Reza Tabandeh, Eskandar Moghimipour, Mahmood Hashemi Tabar, Ata A. Ghadiri, Elham Allah Bakhshi, Mahmoud Orazizadeh, Mohammad Ali Ghafari
Article
Pharmacology & Pharmacy
Mohammad Taghi Mansouri, Hossein Rajabi Vardanjani, Ali Asghar Hemmati, Mohammad Reza Tabandeh, Anahita Rezaie, Marzie Pashmforosh, Kambiz Ahmadi Angali
JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS
(2019)
Article
Pharmacology & Pharmacy
Naeem Erfani Majd, Hajar Azizian, Mohammad Reza Tabandeh, Ali Shahriari
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
(2019)
Article
Reproductive Biology
Haolin Li, Xiaomeng Pei, Hao Yu, Wei Wang, Dagan Mao
Summary: This study investigated the effects of APN/AdipoRon on autophagy and apoptosis in goat luteal cells, and found that autophagy and apoptosis play important roles in the structural regression of goat corpus luteum.
Article
Reproductive Biology
Yan-Qiu Wang, He-Xuan Qu, Yan-Wei Dong, Jia-Jia Qi, Hua-Kai Wei, Hao Sun, Hao Jiang, Jia-Bao Zhang, Bo-Xing Sun, Shuang Liang
Summary: This research reveals the crucial role of Ferroptosis Suppressor Protein 1 (FSP1) in regulating the development and quality of porcine early embryos. Inhibition of FSP1 impairs blastocyst formation, induces glutathione-independent ferroptosis, and leads to oxidative stress due to mitochondrial dysfunction.
Article
Reproductive Biology
Xiong Lai, Ruizhuo Liu, Mengyu Li, Yaochun Fan, Hongxia Li, Guotao Han, Ruijie Guo, Hairui Ma, Huimin Su, Wanjin Xing
Summary: This study identifies WDR54 as a protein involved in sperm-oocyte fertilization and shows that it interacts with IZUMO1 and JUNO. The formation of the JWIJ complex on the oocyte surface suggests its importance in sperm-oocyte adhesion and fusion. This discovery provides new insights into the mechanisms of mammalian sperm-oocyte adhesion and fusion.
Article
Reproductive Biology
S. Nandi, B. Sampath Kumar, P. S. P. Gupta, S. Mondal, V. Girish Kumar
Summary: This study examined the effects of plant bioactive compounds on the survival and growth parameters of ovine preantral follicles granulosa cells (GCs) and the expression of key developmental genes. The results showed that KAE, MYR and QUE had dose-dependent responses on the morphological and functional parameters of the cells, with KAE being the most potent in augmenting ovarian functions.
Article
Reproductive Biology
Francisco E. Martin-Cano, Gemma Gaitskell-Phillips, Laura Becerro-Rey, Eva da Silva, Javier Masot, Eloy Redondo, Antonio Silva-Rodriguez, Cristina Ortega-Ferrusola, Maria Cruz Gil, Fernando J. Pena
Summary: The presence of a more efficient glycolysis mechanism depending on pyruvate in stallion spermatozoa can counteract the detrimental effects of higher glucose concentrations. Incubating spermatozoa with 10 mM pyruvate in a modified Tyrode's media with 67 mM glucose showed increased motility and maintained viability. This improvement is attributed to the conversion of lactate to pyruvate and increased NAD(+) enhancing glycolysis efficiency.
Article
Reproductive Biology
Thanida Sananmuang, Denis Puthier, Catherine Nguyen, Kaj Chokeshaiusaha
Summary: Ongoing progress in mRNA-Sequencing technologies has contributed to the refinement of assisted reproductive technologies. This study utilized mRNA-Seq datasets of various mammalian species to analyze differential transcript usage (DTU) and identified ten cross-species DTU genes. Gene Ontology (GO) term enrichment analysis revealed the involvement of these genes in RNA and cell-cycle control mechanisms, suggesting their importance during oocyte maturation. Further exploration of these genes' transcript isoforms may lead to the discovery of novel markers for reproductive technologies.
Article
Reproductive Biology
Chenglei Song, Zhe Zhang, Yilin Wei, Yaqing Dou, Kunlong Qi, Xiuling Li, Feng Yang, Xinjian Li, Kejun Wang, Ruimin Qiao, Xuelei Han
Summary: In this study, the changes in protein levels in boar sperm with different liquid preservation abilities were analyzed. Key proteins related to sperm liquid preservation ability were identified. The findings provide new insights into the molecular mechanisms of boar sperm liquid preservation ability.
Article
Reproductive Biology
Genevieve M. VanWye, Emily G. Smith, Christine Spinka, Michael F. Smith, Matthew C. Lucy, Jordan M. Thomas
Summary: A series of experiments evaluated treatment schedules for controlling the estrous cycle in beef heifers. The results showed that the duration of progestin treatment and the timing of prostaglandin administration had an impact on estrus expression and pregnancy rates.
Article
Reproductive Biology
Hongwei Duan, Shuai Yang, Longfei Xiao, Shanshan Yang, Zhenxing Yan, Fang Wang, Xiaofei Ma, Lihong Zhang, Yong Zhang, Junjie Hu, Xingxu Zhao
Summary: This study first elucidated the mechanism by which melatonin regulates progesterone secretion in the corpus luteum of sheep, namely by promoting progesterone secretion through the regulation of autophagy. This has important implications for further exploring the role of melatonin in regulating sheep ovarian function.
Article
Reproductive Biology
Zhijie Zheng, Yingfang Guo, Yonghui Zheng, Haichong Wu
Summary: This study demonstrates that miR-92b plays a protective role in LTA-induced endometritis by targeting FZD10 and reducing the production of pro-inflammatory cytokines, thus alleviating uterine injury.
Article
Reproductive Biology
Areeg Almubarak, Sanghoon Lee, Il-Jeoung Yu, Yubyeol Jeon
Summary: This study found that Nobiletin (NOB) can promote the cryosurvival and embryo development of porcine sperm after in vitro fertilization (IVF). The addition of NOB improves sperm motility, acrosome integrity, viability, and mitochondrial membrane potential, reduces lipid peroxidation, and increases cleavage and blastocyst formation rates. Furthermore, NOB treatment upregulates the expression of genes related to pluripotency and cell differentiation in the resulting embryos.
Article
Reproductive Biology
Yuan Li, Lishu Li, Wenjie Xiong, Xing Duan, Huaming Xi
Summary: This study investigated the cytotoxicity and toxicological mechanisms of fluorochloridone (FLC) on cultured goat Sertoli cells. The results showed that FLC exposure induced oxidative stress, promoted apoptosis and autophagy, inhibited lysosomal biogenesis, and blocked autophagic flux in goat Sertoli cells. FLC also caused mitochondrial dysfunction and disturbed mitophagy, leading to cell apoptosis. The antioxidant N-acetyl-L-cysteine (NAC) reduced FLC-induced ROS accumulation and reversed the disorder of autophagy levels.
Article
Reproductive Biology
Gabriela Ramos Leal, Thais de Almeida Oliveira, Mariana Pedrosa de Paula Guimaraes, Lucas Francisco Leodido Correia, Erlandia Marcia Vasconcelos, Joanna Maria Goncalves Souza-Fabjan
Summary: This study investigated the time course of lipid accumulation during IVM and the effects of lipid modulators on cat oocytes. The results showed that adding lipid modulators can reduce lipid content and improve viability after cryopreservation.
Article
Reproductive Biology
Isabella Rio Feltrin, Amanda Guimaraes da Silva, Cecilia Constantino Rocha, Priscila Assis Ferraz, Paola Maria da Silva Rosa, Thiago Martins, Juliano Coelho da Silveira, Milena Lopes Oliveira, Mario Binelli, Guilherme Pugliesi, Claudia Maria Bertan Membrive
Summary: The study evaluated the effects of E2 treatment on Nelore heifers on day 15 of the estrous cycle, finding that E2 promoted an increase in PGFM concentrations and accelerated functional and structural luteolysis by upregulating the expression of PGR and OXTR. This suggests that within 3 hours after E2 stimulus, the expression of these receptors is associated with triggering luteolysis in cattle.
Article
Reproductive Biology
Aline Matos Arrais, Angelo Jose Burla Dias, Claudio Luiz Melo de Souza, Alinne Gloria Curcio, Marco Roberto Bourg de Mello
Summary: This study evaluated the effect of phospholipase C (PLC) on the capacitation of cryopreserved ovine semen. The results showed that the inhibitor U73122 can prevent premature capacitation and acrosome reaction induced by the freezing procedure, without affecting the kinetics and integrity of the sperm membranes.