4.0 Article

Stereoselective synthesis of 2-azetidinylglycine and aminopyrrolidone derivatives from Garner's aldehyde

Journal

TETRAHEDRON-ASYMMETRY
Volume 20, Issue 11, Pages 1213-1216

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2009.04.010

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Funding

  1. DST, New Delhi [SR/Sl/OC-51/2005]

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A new route to two hitherto unknown 2-azetidinylglycine derivatives and an aminopyrrolidone derivative has been developed which featured a diastereoselective conjugate addition of benzyl amine to an alpha,beta-unsaturated ester derived from Garner's aldehyde as the key step. (C) 2009 Elsevier Ltd. All rights reserved.

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