4.4 Article

Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water

Journal

TETRAHEDRON LETTERS
Volume 55, Issue 29, Pages 3856-3859

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.05.082

Keywords

Arylation; Copper catalysis; Diaryliodonium salts; C-N cross coupling; Mild reaction conditions

Funding

  1. National Nature Science Foundation of China (NSFC) [21272069]
  2. Fundamental Research Funds for the Central Universities
  3. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

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An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields. (C) 2014 Elsevier Ltd. All rights reserved.

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