A novel approach for the synthesis of Crizotinib through the key chiral alcohol intermediate by asymmetric hydrogenation using highly active Ir-Spiro-PAP catalyst

Title
A novel approach for the synthesis of Crizotinib through the key chiral alcohol intermediate by asymmetric hydrogenation using highly active Ir-Spiro-PAP catalyst
Authors
Keywords
-
Journal
TETRAHEDRON LETTERS
Volume 55, Issue 9, Pages 1528-1531
Publisher
Elsevier BV
Online
2014-01-21
DOI
10.1016/j.tetlet.2014.01.053

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