Article
Chemistry, Multidisciplinary
Ghanshyam Mali, Badrodin A. Shaikh, Shivani Garg, Akhilesh Kumar, Sudipta Bhattacharyya, Rohan D. Erande, Asha Chate
Summary: This study introduced an efficient taurine-catalyzed green multicomponent approach for synthesizing therapeutic core dihydropyrano[2,3-c]pyrazoles, leading to the development of novel compounds with potential antistaphylococcal properties. The synthesized derivatives demonstrated promising interactions with wild-type and antibiotic-resistant variants of dihydrofolate reductase, highlighting their potential as future therapeutic agents against antibiotic-resistant pathogenic Staphylococcus aureus strains.
Article
Chemistry, Organic
Farzaneh Mohamadpour
Summary: We developed a green synthesis method for dihydropyrano[2,3-c]pyrazole scaffolds using photo-induced electron transfer reaction catalyzed by acridine yellow G. This method offers high yields, energy efficiency, and environmental friendliness.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Ahmed M. Fouda, Mohammed A. A. El-Nassag, Ahmed A. Elhenawy, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin Elbehairi, Mohammed M. Alam, Ahmed M. El-Agrody
Summary: A series of pyrano[2,3-c]pyrazole compounds were synthesized, characterized structurally, evaluated for cytotoxic activity against multiple cancer cell lines, and studied for their active sites and biological activity. Some compounds showed strong and selective cytotoxic activities against the cancer cell lines.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari, Jaber Dadashi
Summary: In this study, a facile and cost-effective method for synthesizing magnetic copper ferrite nanoparticles supported on IRMOF-3/GO was reported. The synthesized nanocatalyst exhibited high catalytic activity in a one-pot reaction and possessed various advantages including wide substrate compatibility, short reaction times, excellent yields, little catalyst loading, good reusability, and high efficiency.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Sourav Chakraborty, Bhaswati Paul, Utpal Chandra De, Ramalingam Natarajan, Swapan Majumdar
Summary: Here, we describe a green and efficient method for the synthesis of pyrano[2,3-c]pyrazole derivatives using a three-component strategy in a water-SDS-ionic liquid system. The method offers high yields, eco-friendly conditions, chromatography-free purification, and recyclability of the reaction medium. The selectivity of the process is controlled by the N-substituent present in the pyrazolinone.
Article
Materials Science, Multidisciplinary
Harminder Singh, Pratibha, Anil Kumar, Jaspreet Kaur Rajput
Summary: BiFeO3 nanoparticles were successfully utilized as a catalyst for the synthesis of pyrano[2,3-c] pyrazoles. The nanoparticles were synthesized through a simple auto-combustion route and characterized using various techniques. The catalytic performance was evaluated for the creation of pyrano[2,3-c] pyrazoles.
Article
Chemistry, Multidisciplinary
Enayatollah Sheikhhosseini, Mahdieh Yahyazadehfar
Summary: The recyclable heterogeneous cluster bud Fe-MOF@Fe3O4 'nanoflower' composite (CB Fe-MOF@Fe3O4 NFC) was synthesized successfully using Fe(NO3)(3)& BULL;9H(2)O, 8-hydroxyquinoline sulfate monohydrate, and Fe3O4 nanoparticles by microwave irradiation. The CB Fe-MOF@Fe3O4 NFC samples were characterized by various techniques and showed excellent catalytic activity. They were used for the synthesis of dihydropyrano[3, 2-c]chromene derivatives, and the optimized reaction conditions had several advantages.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Organic
Nitishkumar S. Kaminwar, Sunil U. Tekale, Rajkumar U. Pokalwar, Laszlo Kotai, Rajendra P. Pawar
Summary: A rapid and efficient one-pot three-component synthesis of two different derivatives was achieved by using copper nanoparticles grafted on carbon microspheres as catalyst, with key features including heterogeneous catalysis, mild reaction conditions, and excellent product yields.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Organic
Zong Han
Summary: An efficient and suitable method for synthesizing dihydro-pyrano-[2,3-c]pyrazoles has been developed. The method shows excellent atom economy, high yields, operational simplicity, and easy work-up.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Fatemeh Sameri, Akbar Mobinikhaledi, Mohammad Ali Bodaghifard
Summary: Core/shell CaO@SiO2-SO3H nanoparticles were prepared by stabilizing sulfonic acid on the surface of silica-coated CaO nanoparticles. The catalyst was used for the green synthesis of dihydropyrano[2,3-c]pyrazoles and tetrahydrobenzo[b]pyrans with good to excellent yields. It could be recycled and reused for six runs without significant loss of activity.
Article
Materials Science, Multidisciplinary
Forozan Heydari, Mohsen Bakhtiarian, Mohammad Mehdi Khodaei
Summary: This study demonstrates the preparation and catalytic application of a magnetic nanocatalyst based on k-Carrageenan. The Fe3O4@Carr-Met nanoparticles were prepared by coating magnetic Fe3O4 nanoparticles with Carr and Met. These nanoparticles exhibited excellent activity for the synthesis of dihydropyrano [2, 3-c] pyrazoles. The Fe3O4 core allowed for effective magnetic separation, and the catalyst showed advantages such as easy preparation, use of a benign solvent system, enhanced activity, and reusability.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2023)
Article
Chemistry, Physical
Sarika Kondabanthini, Naresh Kumar Katari, Malempati Srimannarayana, Rambabu Gundla, Ravikumar Kapavarapu, Manojit Pal
Summary: The pyrano[2,3-c]pyrazole framework was used for designing and synthesizing potential SIRT1 inhibitors. Through sonochemical synthesis, in silico and in vitro studies, small molecules based on pyrano[2,3-c]pyrazole were identified as potential inhibitors of SIRT1.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Organic
Venkata Hema Kumar, Ramana Tamminana
Summary: A facile and efficient one-pot multi-component protocol for the synthesis of pyrano[2,3-c]pyrazoles has been developed using a cheap and readily available copper catalyst under moderate reaction conditions. The target products are obtained from aromatic aldehyde via Knoevenagel condensation and Michael addition reactions. The anti-cancer activity of the target products has been evaluated, and the practical utility of this method has also been attempted.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Farzaneh Mohamadpour
Summary: This catalyst-free synthesis of dihydropyrano[2,3-c]pyrazole scaffolds in a green medium of glycerol is efficient and environmentally friendly. The method allows for high yields, easy work-up, and reusability of the medium without significant loss of activity, making it beneficial for industrial applications and addressing environmental concerns.
POLYCYCLIC AROMATIC COMPOUNDS
(2021)
Article
Chemistry, Multidisciplinary
Arefeh Dehghani Tafti, Bi Bi Fatemeh Mirjalili, Abdolhamid Bamoniri, Naeimeh Salehi
Summary: In this study, nano-eggshell/Ti(IV) was successfully prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The process showed mild conditions, high yields, and reusability of the catalyst, making it a promising approach for organic synthesis.
Article
Chemistry, Multidisciplinary
Mahendra A. Chaudhari, Jitendra B. Gujar, Deepak S. Kawade, Pravin V. Shinde, Murlidhar S. Shingare
RESEARCH ON CHEMICAL INTERMEDIATES
(2015)
Article
Chemistry, Multidisciplinary
Pravin V. Shinde, Jitendra B. Gujar, Bapurao B. Shingate, Murlidhar S. Shingare
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
(2012)
Article
Chemistry, Organic
Pravin V. Shinde, Vilas B. Labade, Jitendra B. Gujar, Bapurao B. Shingate, Murlidhar S. Shingare
TETRAHEDRON LETTERS
(2012)
Article
Chemistry, Organic
Jitendra B. Gujar, Mahendra A. Chaudhari, Deepak S. Kawade, Murlidhar S. Shingare
TETRAHEDRON LETTERS
(2014)
Article
Chemistry, Organic
Jitendra B. Gujar, Raghunath N. Zambare, Murlidhar S. Shingare
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL
(2022)
Article
Chemistry, Multidisciplinary
Deepak S. Kawade, Surekha N. Deshmukh, Jitendra B. Gujar, Murlidhar S. Shingare
ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY
(2015)
Article
Chemistry, Multidisciplinary
Mahendra A. Chaudhari, Jitendra B. Gujar, Deepak S. Kawade, Nivrutti R. Jogdand, Murlidhar S. Shingare
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
