4.4 Article

Asymmetric total synthesis of (+)-sattazolin

Journal

TETRAHEDRON LETTERS
Volume 54, Issue 2, Pages 192-194

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.10.124

Keywords

Sattazolin; Antiviral; Indole acyloin; Natural product

Funding

  1. Fort Lewis College
  2. Research Corporation for Science Advancement
  3. Division Of Undergraduate Education
  4. Direct For Education and Human Resources [1068341] Funding Source: National Science Foundation

Ask authors/readers for more resources

The first asymmetric total synthesis of the antiviral natural product (+)-sattazolin is reported. The total synthesis allowed for unambiguous assignment of the absolute configuration of the hydroxyl bearing stereocenter. Strategies to circumvent an unanticipated alpha-ketol rearrangement encountered in the final steps are also outlined. (C) 2012 Elsevier Ltd. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available