Journal
TETRAHEDRON LETTERS
Volume 54, Issue 8, Pages 929-931Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.12.009
Keywords
N-formylation; Amines; Amino acids; Amino esters; Formamide; Sodium methoxide; Amidation
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A simple and convenient method for the N-formylation of primary and secondary amines including amino acids has been developed utilizing formamide and sodium methoxide in moderate to excellent yield. This reagent is also utilized for one pot conversion of compounds having amino esters to N-formyl amides. (C) 2012 Elsevier Ltd. All rights reserved.
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