Article
Chemistry, Multidisciplinary
Kan Zhang, Yanxiu Yao, Wenjin Sun, Rui Wen, Yanyan Wang, Huaming Sun, Weiqiang Zhang, Guofang Zhang, Ziwei Gao
Summary: The newly designed T-NHC carbenes effectively accelerated the transmetalation reaction, leading to the efficient synthesis of a variety of ynone compounds through coupling reactions. Both triazine wingtips and NHCs played key roles in the putative Pd/Pd catalytic cycle with high TON and TOF.
CHEMICAL COMMUNICATIONS
(2021)
Review
Biochemistry & Molecular Biology
Denisa Leonte, Daniel Ungureanu, Valentin Zaharia
Summary: This review discusses the synthesis and biological activity of flavones and related compounds, such as flavonols and aurones. It highlights the anticancer, antioxidant, and antimicrobial properties of natural and synthetic flavones and aurones, and summarizes the most promising methods for their synthesis. The review also focuses on the development of new effective antimicrobial derivatives and identifies the most promising antimicrobial agents. Overall, the review provides valuable insights into the synthesis and biological potential of flavones and related compounds.
Article
Chemistry, Organic
Gang Xie, Jianan Zhan, Mingzhong Cai, Bin Huang
Summary: A highly efficient method for carbonylative cyclization has been developed using a supported palladium catalyst. This method allows for the synthesis of diverse compounds from readily available starting materials with high yields under specific conditions. The catalyst can be easily recovered and reused multiple times without significant loss of its catalytic efficiency.
SYNTHESIS-STUTTGART
(2023)
Article
Chemistry, Organic
Hui Xu, Ming-Jun Li, Hong Chen, Fei-Hong Huang, Qi-Yue Zhu, Guan-Wu Wang, Ze Zhang
Summary: A novel and efficient multi-component reaction has been developed for the synthesis of polysubstituted pyrroles. This protocol offers several advantages including mild reaction conditions, broad substrate scope, and high efficiency.
Article
Chemistry, Organic
Lin Li, Xin-Lian Liu, Zhuang Qi, Ai-Hua Yang, Ai-Jun Ma, Jin-Bao Peng
Summary: A palladium-catalyzed carbonylative Sonogashira/annulation reaction has been developed for the synthesis of indolo[1,2-b]isoquinolines, which establishes three C-C bonds and a C-N bond in one step.
Article
Chemistry, Organic
Zebiao Zhou, Bin Huang, Mingzhong Cai
Summary: A highly efficient heterogeneous palladium-catalyzed carbonylative annulation of 2-iodoanilines and acid anhydrides has been developed, providing a novel method for the assembly of 2-alkylbenzoxazinones with high functional group tolerance. The supported palladium complex used in the reaction can be easily separated, recovered, and reused up to seven times with consistent catalytic efficiency.
SYNTHETIC COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Amr Elagamy, Ranjay Shaw, Chandan Shah, Ramendra Pratap
Summary: An efficient iodine-mediated method has been developed for the synthesis of functionalized 2-(methylthio)-4H-chromen-4-ones, which serve as key precursors for various chemical reactions. Mechanistically, the intramolecular cyclization of ketene dithioacetal was observed to proceed through a radical pathway. 3-Halo-2-(methylthio)-4H-chromen-4-ones were obtained via various two- or one-pot halogenation approaches.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Hui Xu, Hong Chen, Xiao Hu, Guang Xuan, Pinhua Li, Ze Zhang
Summary: An iodine-promoted domino reaction method has been discovered, which allows for the efficient synthesis of a variety of 1,2,4-trisubstituted 5-(o-hydroxybenzoyl)imidazoles. The reaction proceeds in a consecutive manner, involving Michael addition, iodination, cyclization from intramolecular nucleophilic substitution, and dehydrogenative aromatization from spiro ring opening.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yongzheng Ding, Jianing Wu, Hanmin Huang
Summary: Double C-H bond activation enables a fast reaction pathway to cyclic compounds, providing an efficient tool for synthesizing valuable molecules. However, the cyclization reaction through double C-H bond activation at one carbon atom is largely unknown. Here, we report a carbonylative formal cycloaddition of alkylarenes with imines via double benzylic C-H bond activation at one carbon atom, allowing for a direct synthesis of beta-lactams from easily accessible alkylarenes and imines, which paves the way for the development of annulation reactions through double C-H bond activation at one carbon atom.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Organic
Jin Xi, Ding Wang, Jinxia Hu, Huan Shen, Tao Wang, Zunting Zhang
Summary: A method for synthesizing benzo[f]quinoline derivatives via photoinduced 6 pi-electrocyclization has been developed. The reaction conditions are mild, and the yields are high without the need for transition metal catalysts or additives.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Plant Sciences
Guilherme S. Caleffi, Alice S. Rosa, Luana G. de Souza, Joao L. S. Avelar, Sarah M. R. Nascimento, Vitor M. de Almeida, Amanda R. Tucci, Vivian N. Ferreira, Alcides J. M. da Silva, Osvaldo A. Santos-Filho, Milene D. Miranda, Paulo R. R. Costa
Summary: In this study, a series of 25 aurone compounds with different oxygenated groups were designed, synthesized, and tested for their anti-SARS-CoV-2 activity. Twelve compounds exhibited significant activity with EC50 < 3 μM, and five compounds showed even higher activity with EC50 < 1 μM without cytotoxic effects. The most potent compound, aurone 8q, was 2 to 3 times more effective than the polyphenolic flavonoids myricetin and baicalein. Molecular dynamic calculations suggested that these aurones may bind to another SARS-CoV-2 protein target.
JOURNAL OF NATURAL PRODUCTS
(2023)
Article
Chemistry, Organic
Gang Yang, Lin Yao, Guojiang Mao, Guo-Jun Deng, Fuhong Xiao
Summary: We have reported a metal-free protocol for the synthesis of indenoquinolinones and 2-substituted quinolines via [4 + 2] cycloaddition reaction using readily available 2-aminobenzaldehydes and ketones as starting materials. Different quinoline derivatives can be selectively synthesized by changing the type of ketones. O-2 and dimethyl sulfoxide (DMSO) as co-oxidants play an important role in the synthesis of indenoquinolinones. This condensation/oxidation strategy involves the formation of C-N, C-C, and C-O bonds, with the advantages of high yields and a broad substrate range.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Gang Yang, Lin Yao, Guojiang Mao, Guo-Jun Deng, Fuhong Xiao
Summary: A metal-free protocol for the synthesis of indenoquinolinones and 2-substituted quinolines using readily available 2-aminobenzaldehydes and ketones has been reported. Different quinoline derivatives can be selectively synthesized by altering the type of ketones.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Siqi Wang, Shuwei Li, Liangcai Liu, Jun Ying, Xiao-Feng Wu
Summary: Amide-containing indolo-[2,1-a]isoquinoline scaffolds were synthesized by palladium-catalyzed carbonylative cyclization of alkene-tethered indoles with nitro-arenes. Using Mo(CO)6 as the CO source and reductant, and nitroarenes as the nitrogen source, this reaction yielded various amide-containing indolo[2,1-a]isoquinoline derivatives in good yields. Additionally, the late-stage modifications of bioactive molecules using this protocol were demonstrated.
Article
Chemistry, Organic
Chao Yang, Lijun Shi, Wenlong Wang, Ji-Bao Xia, Fuwei Li
Summary: The well-developed carbonylative synthesis of varied and useful complex molecules with CO is achieved through the rhodium-catalyzed modular carbonylative aminobenzoylation of alkenes with acylaniline under ambient pressure of CO/O-2. The reaction involves the dual cleavage of N-H and C-H bonds and provides moderate-to-high yields of various poly(hetero)cyclic alkylarylketones. The synthetic transformations of the products were also investigated.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Review
Chemistry, Multidisciplinary
Li Sun, Kelei Zhuo, Yujuan Chen, Quanzhou Du, Suojiang Zhang, Jianji Wang
Summary: This review introduces the use of ionic liquid (IL) electrolytes combined with redox active species to enhance the energy density of supercapacitors (SCs). The introduction of redox active species contributes to pseudocapacitance and various IL-REs and their energy storage mechanisms are discussed. Future research needs to address current challenges in order to advance this promising field.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Physical
Hua Li, Xiaodong Hu, Chunfeng Wang, Yujuan Chen, Kelei Zhuo, Jianji Wang
Summary: In this study, an IL-rGA material was prepared using hydrothermal reduction and modification tactics with the assistance of an ionic liquid. The IL-rGA material, with its porous texture and modified surface, enables rapid infiltration and sufficient adsorption of electrolyte ions, resulting in a significant improvement in specific capacitance. By using this material and a specific IL electrolyte, high energy density and power density supercapacitors can be achieved, meeting the requirements of a wider range of electrical facilities.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Chemistry, Physical
Hua Li, Xiaodong Hu, Yujuan Chen, Huanhuan Li, Guangyue Bai, Kelei Zhuo
Summary: Balancing the energy density and power density of supercapacitors is crucial for expanding their application range. This study demonstrates a feasible approach to achieve this balance through the design and synthesis of hierarchically porous graphene aerogels containing doped-heteroatoms and matching with ionic liquid electrolyte.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Zhijun Guo, Guangyue Bai, Xize Zhan, Kelei Zhuo, Jianji Wang, Yujie Wang
Summary: A coassembly strategy for a supramolecular vector/drug was proposed, which uses biocompatible molecules to achieve pH-responsive and sustained release functions. The self-assembling behaviors of the components and the functions of the vector/drug were characterized. The results demonstrate that this coassembly method is a simple and effective approach.
Article
Chemistry, Physical
Yuhua Zhao, Yujuan Chen, Quanzhou Du, Kelei Zhuo, Lifang Yang, Dong Sun, Guangyue Bai
Summary: This study investigates the relationship between the pore size of porous carbon electrode materials and the ion size and shape of ionic liquids, showing potential for improving the capacitive performance of supercapacitors. Matching different IL mixtures with carbon-based electrode materials of specific pore size distributions could offer a new strategy to enhance supercapacitor performance.
Article
Chemistry, Multidisciplinary
Shumin Fan, Yunxiang Li, Rujun Wang, Wenwen Ma, Yipei Shi, Wenxiu Fan, Kelei Zhuo, Guangri Xu
Summary: Intelligent surfaces with controlled wettability have been widely studied for industrial oily wastewater treatment. In this study, a hygro-responsive superhydrophilic/underwater superoleophobic coating was fabricated through liquid-phase deposition of SiO2 grafted with perfluorooctanoic acid. The surface wettability could transform from superhydrophilicity/underwater superoleophobicity to superhydrophobicity/superoleophilicity, achieving separation efficiency higher than 99%.
Article
Chemistry, Physical
Kelei Zhuo
Summary: In this study, the relationship between Langmuir adsorption coefficients and Gibbs free energy change is derived in detail, and the applicable conditions for correct application and avoiding misuse are analyzed and discussed.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Zezhong Zhang, Dong Sun, Rumeng Feng, Shengkai Yang, Kelei Zhuo
Summary: A method of graphene preparation through aqueous phase exfoliation (APE) assisted by sulfonated cobalt phthalocyanine (CoPcS) as the stabilizer is reported. This method can achieve high yield of graphene and improve the protection performance of coatings.
Article
Chemistry, Multidisciplinary
Zhijun Guo, Guangyue Bai, Wenqi Zhao, Ling Yang, Tingru Du, Kelei Zhuo, Jianji Wang, Yujie Wang
Summary: Due to the unique geometric structure of dendritic amphiphiles, their micelles can provide a large void space, which offers a new research focus and approach for micellar functionalization. In this study, we used the void space to construct a UV-responsive micelle system of mixed dendritic amphiphile and cationic azobenzene surfactant. The results showed that the micelles can inhibit the UV response of the trans-isomer and activate the thermal relaxation of the cis-isomer, suggesting potential applications in light-controlled smart nanocarriers.
Article
Electrochemistry
Mingming Zhang, Yujuan Chen, Lihong Liu, Kelei Zhuo
Summary: The corrosion inhibition effect of Artemisia capillaris leaf extract (ACLE) on Q235 steel in 1 M HCl at temperatures ranging from 25-65°C was analyzed using weight loss measurements, electrochemical tests, and quantum chemical calculations. ACLE was found to have a significant corrosion inhibition effect, with an inhibition efficiency of 99% at 10 g/L ACLE at 25°C. Caffeic acid was identified as a major effective corrosion inhibition component in ACLE. The adsorption of ACLE on the Q235 steel surface was a spontaneous process and followed the Langmuir adsorption isotherm model.
Article
Engineering, Environmental
Rumeng Feng, Yujuan Chen, Lifang Yang, Quanzhou Du, Kelei Zhuo
Summary: In this study, an ethyl viologen-functionalized reduced graphene oxide composite (EV-RGO) was synthesized by one-step hydrothermal method. The ethyl viologen cations are anchored on the RGO sheets through different interactions, making EV-RGO more stable and reversible as an electrode material. The presence of viologen cations with ethyl groups effectively suppresses the stacking of RGO sheets and expands their interlayer spacing. In an ethyl-methylimidazolium tetrafluoroborate ionic liquid electrolyte, the electrochemical performance of EV-RGO is enhanced due to the synergistic contributions of electric double-layer capacitance and pseudocapacitance. The specific capacitance of EV-RGO as a negative electrode material for supercapacitors reaches 222.7 F g(-1) at a current density of 0.5 A g(-1). An asymmetric supercapacitor device (EVRGO//AC ASC) exhibits an energy density of 64.1 Wh kg(-1) at a power density of 888 W kg(-1). This work offers an advanced strategy for fabricating high-performance supercapacitors using organic molecule-modified graphene composites.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Electrochemistry
Li Sun, Yujuan Chen, Kelei Zhuo, Dong Sun, Jianming Liu, Jianji Wang
Summary: In this study, a nitrogen-doped Ti3C2Tx-reduced graphene oxide (N-Ti3C2Tx/TiO2-RGO) hybrid material was successfully prepared and matched with a ternary mixed electrolyte. The hybrid material exhibited a 3D cross-linked porous structure for efficient ion transport, while the electrolyte provided a wide electrochemical stability window for redox reactions. The assembled supercapacitor showed enhanced specific capacitance and high energy density at a high-power density.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Physical
Quanzhou Du, Yuhua Zhao, Yujuan Chen, Jianming Liu, Huanhuan Li, Guangyue Bai, Kelei Zhuo, Jianji Wang
Summary: Nitrogen-doped porous carbon nanosheets (NPCNs) with unique structure were studied for their potential application as anode and cathode material in potassium-ion hybrid capacitors (PIHCs). The structural changes of NPCNs during potassiation and depotassiation were analyzed using Raman spectroscopy and transmission electron microscopy. The PIHC device assembled with NPCNs exhibited a superior energy density of 128 Wh kg-1 and a capacity retention of 90.8% after 9000 cycles. This research contributes to the development of double-functional self-matching materials for high-performance hybrid energy storage devices.
GREEN ENERGY & ENVIRONMENT
(2023)
Correction
Chemistry, Multidisciplinary
Yuhua Zhao, Yujuan Chen, Kelei Zhuo, Quanzhou Du, Dong Sun, Zhiyong Li, Huiyong Wang, Changling Yan, Jianji Wang
Summary: The paper titled "An azobenzene-modified redox-active ionic liquid electrolyte for supercapacitors" by Yuhua Zhao et al. presents a new infrared radiation correction method applied to the electrolyte of supercapacitors, using azobenzene-modified redox-active ionic liquid.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Yuhua Zhao, Yujuan Chen, Kelei Zhuo, Quanzhou Du, Dong Sun, Zhiyong Li, Huiyong Wang, Changling Yan, Jianji Wang
Summary: A new redox-active ionic liquid has been demonstrated to improve the capacitance performance of carbon-based supercapacitors by introducing it into the electrolyte. This opens up a new pathway for developing high-energy supercapacitors.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
