Journal
TETRAHEDRON LETTERS
Volume 53, Issue 48, Pages 6479-6482Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.09.039
Keywords
Metal-free; Oxidation; Amides; Alcohols; N,N-Disubstituted formamides
Categories
Funding
- National Natural Science Foundation of China [20832001, 20972065, 21074054, 21172106]
- National Basic Research Program of China [2007CB925103, 2010CB92330]
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A facile and efficient protocol for the synthesis of amides has been developed in the absence of transition metals. The reaction was performed with a catalytic amount of n-Bu4NI and aqueous TBHP as an oxidant. Various alcohols with N,N-disubstituted formamides were examined to furnish the desired products in good yields. (C) 2012 Elsevier Ltd. All rights reserved.
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