4.4 Article

Tandem oxidation/bromination of ethyl aromatics to α,α-dibromoacetophenones with molecular oxygen under visible light irradiation

Journal

TETRAHEDRON LETTERS
Volume 52, Issue 29, Pages 3821-3824

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.05.077

Keywords

Photooxidation; Bromine source; Aerobic; Ethylbenzene; alpha,alpha-Dibromoacetophenone

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The facile synthesis of alpha,alpha-dibromoacetophenones from ethyl-substituted aromatics by aerobic photooxidation has been developed. This synthetic method achieves oxidative dibromination of aromatic ethyl groups by using inexpensive and easily handled bromine sources, harmless visible light and molecular oxygen. (C) 2011 Elsevier Ltd. All rights reserved.

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