Article
Multidisciplinary Sciences
Yasrib Qurishi, Vidya Devanathadesikan Seshadri, Mohammed Mustafa Poyil, Jeyaseelan Benjamin Franklin, Deepak Arun Apte, Mohammed H. Karrar Alsharif, Rajaian Pushpabai Rajesh, Randa Mohammed Zaki
Summary: This study focused on purifying fractions of Eudistoma kaverium to evaluate its anticancer activity. A specific fraction, EK-7, identified as a sterol Cholesta-4,6-dien-3-ol, exhibited potent cytotoxicity and induced apoptosis by targeting the G(0)/G(1) phase, suggesting its potential as a chemotherapeutic agent for cancer treatment.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Fiona Sprang, Jana Klein, Siegfried R. Waldvogel
Summary: A novel electrosynthetic protocol is reported for the direct conversion of 4-hydroxybenzaldehydes to valuable benzoquinones. The transformation is conducted through anodic oxidation, minimizing waste by eliminating terminal oxidants and redox mediators. Graphite serves as a metal-free anode material. A wide range of substituents, including halogens, are tolerated in this electrochemical protocol, with quinones selectively obtained in up to 99% yield. The compatibility of the protocol with electrochemical flow synthesis is demonstrated, and its application to lignosulfonate yields quinones in up to 7.6 wt%.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Engineering, Environmental
Pei Li, Shang-Feng Yang, Zi-Lin Fang, Hao-Ran Cui, Sen Liang, Hong-Yu Tian, Bao-Guo Sun, Cheng-Chu Zeng
Summary: An efficient one-pot electrochemical protocol for the synthesis of 2-aminothiazoles has been described. The use of thioureas mediated by iodide ion in the electrolysis of ketones allows for the generation of satisfactory yields of the corresponding 2-aminothiazoles. The proposed key active species is the in-situ generated alpha-iodoketone.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Richard C. D. Brown
Summary: This article provides an overview of the work conducted by the author's research group in developing flow electrolysis cells and applying them in organic electrosynthesis. The importance of cell design in achieving good performance in laboratory electrosynthesis is emphasized, with examples of flow electrosyntheses provided.
Article
Chemistry, Organic
Shang-Feng Yang, Pei Li, Zi-Lin Fang, Sen Liang, Hong-Yu Tian, Bao-Guo Sun, Kun Xu, Cheng-Chu Zeng
Summary: The electrochemical synthesis of 2-aminothiazoles from active methylene ketones and thioureas assisted by ᴅʟ-alanine using NH4I as a redox mediator has been successfully achieved. The reaction is carried out in an undivided cell with graphite plate electrodes under constant current conditions, resulting in the conversion of various active methylene ketones to the corresponding 2-aminothiazoles. The proposed mechanism involves the in situ generated alpha-iodoketone as the key active species.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Qikun Zhang, Ya'nan Zhao, Liping Yu, Xiaoyang Zhang, Yiling Bei, Bo Tang
Summary: Electrocatalysis is an environmentally friendly synthesis method that can achieve reactions under ambient conditions, such as the green and clean synthesis of ammonia from inexpensive nitrogen.
Article
Materials Science, Ceramics
Yunfei Chen, Mingyong Wang, Aijing Lv, Zhonghua Zhao, Jialiang An, Jintao Zhang, Jiguo Tu, Shuqiang Jiao
Summary: High-purity vanadium carbide (VC) was successfully prepared by one-step co-electrolysis of NaVO3 and CO2 in molten salt, offering a novel and green method for the high value-added utilization of vanadium slag and CO2.
CERAMICS INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Tudor Mocan, Dong Wook Kang, Billy J. Molloy, Hyeonho Jeon, Zeno A. Sparchez, Diren Beyoglu, Jeffrey R. Idle
Summary: The concentrations of two 3-oxo-Delta(4) fetal bile acids in plasma are significantly correlated with the severity of liver cirrhosis as determined by Child-Pugh and MELD scores in adult patients. This suggests that the levels of these fetal bile acids may serve as indicators of liver cirrhosis severity.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Applied
Roland J. -R. Bednarz, Annika S. S. Gold, Jasmin Hammes, Denis F. F. Rohrmann, Silvio Natalello, Moritz Mann, Frank Weinelt, Christopher Brauer, Siegfried R. R. Waldvogel
Summary: The rapidly advancing climate change necessitates the development of more sustainable synthetic pathways for critical chemicals, such as adipic acid or its derivatives. In this study, 3-ethyladipic acid was synthesized through an environmentally benign electrochemical method using 4-ethylcyclohexanol as the precursor, derived from lignin. The production rate of the target compound was significantly enhanced in a scaled and commercially available flow electrolyzer with an increased anodic surface area.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2023)
Article
Electrochemistry
Tatsuya Suga, Naoki Shida, Mahito Atobe
Summary: A novel green system for electrochemical oxidation of alcohols using a column flow cell was demonstrated. The oxidation of 1-phenylethanol and benzaldehyde was promoted by an Au-electrode and an alkaline medium. Modification of a carbon-fiber thread electrode with Au nanoparticles enabled efficient electrochemical oxidation of various alcohols.
ELECTROCHEMISTRY COMMUNICATIONS
(2021)
Article
Biotechnology & Applied Microbiology
Chenyang Yuan, Zhiguo Ma, Yixin Li, Jingxian Zhang, Xiangcen Liu, Suwan Han, Guilin Du, Jiping Shi, Junsong Sun, Baoguo Zhang
Summary: In this study, a strain that could produce 1,4-HP as the main product and 21-hydroxy-20-methyl-pregna-4-ene-3-one as a by-product was developed by blocking steroid nucleus degradation and C19 steroid accumulation in Mycolicibacterium neoaurum. The purity of 1,4-HP was improved to 95.2% by enhancing KSTD activity, and the production was increased by overexpressing NOX and KATE genes, resulting in a yield of 10.5 g/L. This provides a new intermediate for the pharmaceutical steroid industry.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Electrochemistry
Kazuhiro Okamoto, Naoki Shida, Mahito Atobe
Summary: In this study, the electrochemical [3+2] cycloaddition of phenols and alkenes was successfully achieved in a laminar-flow microreactor at an unprecedentedly low electrolyte concentration. The optimization of the reactor configuration prevented the overoxidation of the resulting cycloadducts, and nine dihydrobenzofuran derivatives were synthesized without any oxidant. Additionally, a simple scale-up was enabled by using a parallel stacked flow cell system.
Article
Engineering, Environmental
Weiguang Lv, Dingshan Ruan, Xiaohong Zheng, Li Li, Hongbin Cao, Zhonghang Wang, Yi Zhang, Zhi Sun
Summary: A paired electrolysis method was developed for the simultaneous recycling of valuable metals from spent lithium-ion batteries and the synthesis of persulfate, reducing energy consumption by approximately 30% and improving product quality. This green method has wide application prospects in waste recycling and hydrometallurgical fields due to its low energy consumption and generation of high-value products.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Zhen-Hua Wang, Lei Wei, Ke-Jin Jiao, Cong Ma, Tian-Sheng Mei
Summary: Nickel-catalyzed decarboxylative cross-coupling of indole-3-acetic acids with aryl bromides was achieved using convergent paired electrolysis in an undivided cell. This protocol exhibits good functional group tolerance and does not require chemical redox agents or sacrificial electrodes. Mechanistic studies indicate that the base is essential for decarboxylation and that a Ni-I/Ni-III catalytic cycle is involved in this transformation.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Yu Chen, Jiaojiao Chen, Ke Bai, Zeyi Xiao, Senqing Fan
Summary: The evolution of bubbles during water electrolysis for hydrogen production can cause overpotential, and the electrode surfaces can be covered by these bubbles. This study presents flow-through electrodes with Co-based nanosheets loaded in Ni foam pores, which reduce adhesion between H2 bubbles and the superaerophobic catalyst layer and decrease the size of H2 bubbles. Under the condition of flow-through mode, the timely removal of bubbles from the catalyst surface enables adequate exposure of the catalysts, resulting in a reduction of overpotential for both hydrogen and oxygen evolution reactions. An electrolyzer with flow-through electrodes for alkaline water electrolysis is assembled, achieving a decrease in cell voltage and energy consumption for hydrogen production.
JOURNAL OF POWER SOURCES
(2023)
Article
Electrochemistry
Yu-Ya Hosokawa, Hideki Hakamata, Tomonori Murakami, Sakae Aoyagi, Minpei Kuroda, Yoshihiro Mimaki, Ayumi Ito, Sayaka Morosawa, Fumiyo Kusu
ELECTROCHIMICA ACTA
(2009)
Article
Biochemical Research Methods
Tomonori Murakami, Takao Kawasaki, Akira Takemura, Naoto Fukutsu, Naoyuki Kishi, Fumiyo Kusu
JOURNAL OF CHROMATOGRAPHY A
(2008)
Article
Biochemical Research Methods
Tomonori Murakami, Naoto Fukutsu, Junichi Kondo, Takao Kawasaki, Fumiyo Kusu
JOURNAL OF CHROMATOGRAPHY A
(2008)
Article
Chemistry, Analytical
Tomonori Murakami, Hidetoshi Konno, Naoto Fukutsu, Michinobu Onodera, Takao Kawasaki, Fumiyo Kusu
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2008)
Article
Chemistry, Analytical
Yoko Kawaguchi-Murakami, Naoto Fukutsu, Toshi Kajiro, Tetsuya Araki, Tomonori Murakami, Takao Kawasaki, Naoyuki Kishi, Michiko Konno
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2009)
Article
Biochemistry & Molecular Biology
Tomonori Murakami, Shunji Natsuka, Shin-ichi Nakakita, Sumihiro Hase
GLYCOCONJUGATE JOURNAL
(2007)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
